YAMAMOTOYA TAKESHI

ヤマモトヤタケシ | YAMAMOTOYA TAKESHI

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Metabolism and endocrinology

Research keywords (2)： Glucose and Lipid Metabolism , Diabetes Mellitus

Research theme for competitive and other funds (16)：

2024 - 2027 翻訳後修飾を介した脂質代謝調節機構およびTFGによるその制御メカニズムの解明
2023 - 2026 Hippo/YAP経路へのPin1作用と肝や脂肪組織の肥大、炎症、線維化への関与
2022 - 2025 NASHの炎症、線維化におけるPin1の役割解明と臨床応用への展開
2023 - 2024 肝細胞での摂食・絶食時の代謝応答におけるTrk-fused gene (TFG) の役割
2021 - 2024 糖・脂質代謝における細胞内小胞輸送関連蛋白TFGの関与とその発現制御因子の解明

Show all

Papers (37)：

Yusuke Nakatsu, Yasuka Matsunaga, Mikako Nakanishi, Takeshi Yamamotoya, Tomomi Sano, Takashi Kanematsu, Tomoichiro Asano. Prolyl isomerase Pin1 in skeletal muscles contributes to systemic energy metabolism and exercise capacity through regulating SERCA activity. Biochemical and biophysical research communications. 2024. 715. 150001-150001
Takeshi Yamamotoya, Yukino Ohata, Yasuyuki Akasaka, Shun Hasei, Masa-Ki Inoue, Yusuke Nakatsu, Machi Kanna, Hiroki Yamazaki, Akifumi Kushiyama, Midori Fujishiro, et al. Trk-fused gene plays a critical role in diet-induced adipose tissue expansion and is also involved in thyroid hormone action. PNAS nexus. 2024. 3. 4. pgae150
Yasuyuki Akasaka, Shun Hasei, Yukino Ohata, Machi Kanna, Yusuke Nakatsu, Hideyuki Sakoda, Midori Fujishiro, Akifumi Kushiyama, Hiraku Ono, Akio Matsubara, et al. Auraptene Enhances AMP-Activated Protein Kinase Phosphorylation and Thereby Inhibits the Proliferation, Migration and Expression of Androgen Receptors and Prostate-Specific Antigens in Prostate Cancer Cells. International journal of molecular sciences. 2023. 24. 21
Machi Kanna, Yusuke Nakatsu, Takeshi Yamamotoya, Akifumi Kushiyama, Midori Fujishiro, Hideyuki Sakoda, Hiraku Ono, Koji Arihiro, Tomoichiro Asano. Hepatic Pin1 Expression, Particularly in Nuclei, Is Increased in NASH Patients in Accordance with Evidence of the Role of Pin1 in Lipid Accumulation Shown in Hepatoma Cell Lines. International journal of molecular sciences. 2023. 24. 10
Shunya Aoyama, Yuri Kido, Mayu Kanamoto, Miki Naito, Mikako Nakanishi, Machi Kanna, Takeshi Yamamotoya, Tomoichiro Asano, Yusuke Nakatsu. Prolyl isomerase Pin1 promotes extracellular matrix production in hepatic stellate cells through regulating formation of the Smad3-TAZ complex. Experimental cell research. 2023. 425. 2. 113544-113544

ｍore...

Books (3)：

Diabetes Strategy Vol.7 no.1 2017 Winter
2017
Anti-aging Medicine
2016
medicina Vol.53 No.1
2016

Lectures and oral presentations (46)：

Trk-fused gene (TFG) の脂肪細胞分化および成熟脂肪細胞における役割の検討
(第66回日本糖尿病学会年次学術集会 2023)
骨格筋TFGの肥満形成および神経筋接合部の維持における役割
(第65回日本糖尿病学会年次学術集会 2022)
Trk-fused gene (TFG) の脂肪細胞における代謝制御機構の解明
(第64回日本糖尿病学会年次学術集会 2021)
Trk-fused gene (TFG) の骨格筋機能および肥満発症における役割
(第63回日本糖尿病学会年次学術集会 2020)
脂肪細胞のTrk-fused gene (TFG) はPPARγ発現量およびミトコンドリア機能を調節し, adipose expansionに重要である
(第63回日本糖尿病学会年次学術集会 2020)

ｍore...

Education (3)：

2010 - 2014 The University of Tokyo Graduate School of Medicine PhD course, Internal Medicine
2004 - 2008 The University of Tokyo Faculty of Medicine
2002 - 2004 The University of Tokyo College of Arts and Sciences College of Arts and Sciences

Professional career (1)：

博士(医学) (東京大学)

Work history (3)：

2024/04 - 現在 Nihon University School of Medicine Department of Medicine Assistant Professor
2019/04 - 2024/03 Hiroshima University Graduate School of Biomedical & Health Sciences Assistant Professor
2015/04/01 - 2019/03/31 Hiroshima University, Graduate School of Biomedical and Health Sciences Biomedical Chemistry Assistant Professor

Association Membership(s) (4)：

The Japan Endocrine Society , The Molecular Biology Society of Japan , The Japan Diabetes Society , The Japanese Society of Internal Medicine

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page