Rchr
J-GLOBAL ID:201801016125423703   Update date: Jan. 30, 2024

Isono Kyoichi

Isono Kyoichi
Affiliation and department:
Research field  (5): Medical biochemistry ,  Developmental biology ,  Cell biology ,  Molecular biology ,  Genetics
Research keywords  (8): ノックアウトマウス ,  発生工学 ,  DNA修復 ,  ES細胞 ,  ゲノム編集 ,  老化 ,  がん ,  エピジェネティクス
Research theme for competitive and other funds  (15):
  • 2019 - 2022 転写抑制因子ポリコーム群による幹細胞のゲノム情報を維持する機構の解明
  • 2018 - 2020 がん創薬に向けた新規分子探索法の開発
  • 2017 - 2018 がん発症の分子機構の解明
  • 2014 - 2017 ポリコーム群リクルートメント後の遺伝子発現制御機構の解明
  • 2013 - 2014 代謝とポリコーム群によるがん制御
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Papers (62):
  • Junichiro Takano, Shinsuke Ito, Yixing Dong, Jafar Sharif, Yaeko Nakajima-Takagi, Taichi Umeyama, Yong-Woon Han, Kyoichi Isono, Takashi Kondo, Yusuke Iizuka, et al. PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment. Nature Communications. 2022. 13. 1. 7159-7159
  • Mizuki Kajimoto, Kentaro Suzuki, Yuko Ueda, Kota Fujimoto, Toru Takeo, Naomi Nakagata, Taiju Hyuga, Kyoichi Isono, Gen Yamada. Androgen/Wnt/β-catenin signal axis augments cell proliferation of the mouse erectile tissue, corpus cavernosum. Congenital anomalies. 2022. 62. 3. 123-133
  • Toshitada Takemori, Akiko Sugimoto-Ishige, Hironori Nishitsuji, Yushi Futamura, Michishige Harada, Tomomi Kimura-Someya, Takehisa Matsumoto, Teruki Honma, Miho Tanaka, Masami Yaguchi, et al. Establishment of a Monoclonal Antibody against Human NTCP That Blocks Hepatitis B Virus Infection. Journal of virology. 2022. 96. 5. e0168621
  • Shinji Kumegawa, Gen Yamada, Daiki Hashimoto, Tsuyoshi Hirashima, Mizuki Kajimoto, Kyoichi Isono, Kota Fujimoto, Kentaro Suzuki, Kazuhisa Uemura, Masatsugu Ema, et al. Development of Surgical and Visualization Procedures to Analyze Vasculatures by Mouse Tail Edema Model. Biological procedures online. 2021. 23. 1. 21-21
  • Takashi Kato, Masaki Yamamoto, Yoshitaka Honda, Takashi Orimo, Izumi Sasaki, Kohei Murakami, Hiroaki Hemmi, Yuri Fukuda-Ohta, Kyoichi Isono, Saki Takayama, et al. Augmentation of Stimulator of Interferon Genes-Induced Type I Interferon Production in COPA Syndrome. Arthritis & rheumatology (Hoboken, N.J.). 2021. 73. 11. 2105-2115
more...
MISC (15):
  • Kyo-ichi Isono, Kazumi Nemoto, Yuanyuan Li, Yuki Takada, Rie Suzuki, Motoya Katsuki, Akira Nakagawara, Haruhiko Koseki. Overlapping Roles for Homeodomain-Interacting Protein Kinases Hipk1 and Hipk2 in the Mediation of Cell Growth in Response to Morphogenetic and Genotoxic Signals (vol 26, pg 2758, 2006). MOLECULAR AND CELLULAR BIOLOGY. 2014. 34. 14. 2772-2772
  • Kyo-ichi Isono, Yu-ichi Fujimura, Jun Shinga, Makoto Yamaki, Jiyang O-Wang, Yoshihiro Takihara, Yasuaki Murahashi, Yuki Takada, Yoko Mizutani-Koseki, Haruhiko Koseki. Mammalian Polyhomeotic Homologues Phc2 and Phc1 Act in Synergy To Mediate Polycomb Repression of Hox Genes (vol 25, pg 6694, 2005). MOLECULAR AND CELLULAR BIOLOGY. 2014. 34. 14. 2771-2771
  • M. Matsunawa, R. Yamamoto, M. Sanada, A. Kon, A. Sato-Otsubo, Y. Shiozawa, K. Yoshida, Y. Nagata, T. Yoshizato, M. Otsu, et al. SF3B1 PLAYS AN IMPORTANT ROLE IN THE REGULATION OF HEMATOPOIETIC STEMS CELLS, BUT HAPLOINSUFFICIENCY OF SF3B1 MAY NOT BE SOLELY RESPONSIBLE FOR MYELODYSPLASIA. HAEMATOLOGICA. 2014. 99. 234-235
  • Manabu Matsunawa, Ryo Yamamoto, Masashi Sanada, Aiko Sato, Yusuke Shiozawa, Kenichi Yoshida, Yasunobu Nagata, Ayana Kon, Tetsuichi Yoshizato, Makoto Otsu, et al. Role Of Sf3b1 On Hematopoiesis. BLOOD. 2013. 122. 21
  • Valeria Visconte, Heesun J. Rogers, Ali Tabarroki, Li Zhang, Yvonne Parker, Edy Hasrouni, Reda Z. Mahfouz, Quteba Ebrahem, Kyoichi Isono, Haruhiko Koseki, et al. Splicing Factor (3)b Subunit 1 (SF(3)B1) Heterozygous Mice Manifest a Hematologic Phenotype Similar To Low Risk Myelodysplastic Syndromes With Ring Sideroblasts. BLOOD. 2013. 122. 21
more...
Education (3):
  • 1993 - 1996 Okayama University The Graduate School of Natural Science and Technology
  • 1991 - 1993 University of Shizuoka Graduate School of Nutritional and Environmental Sciences
  • 1987 - 1991 University of Shizuoka School of Food and Nutritional Sciences
Work history (5):
  • 2017/02 - 現在 Wakayama Medical University Laboratory Animal Center Associate Professor
  • 2004/04 - 2017/01 理化学研究所(横浜) 上級研究員
  • 2000/04 - 2004/03 Chiba University Graduate School of Medicine
  • 1998/10 - 2000/03 長寿科学振興財団 リサーチ・レジデント
  • 1996/04 - 1998/09 地球環境産業技術研究機構 研究員
Association Membership(s) (4):
JAPANESE ASSOCIATION FOR LABORATORY ANIMAL SCIENCE ,  日本エピジェネティクス研究会 ,  JAPANESE SOCIETY OF DEVELOPMENTAL BIOLOGISTS ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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