Koji Hayashizaki

ハヤシザキコウジ | Koji Hayashizaki

Affiliation and department：
Job title： Assistant professor

Research field (2)： Bacteriology , Immunology

Research keywords (6)： NKT細胞 , ワクチン , 細菌 , 感染免疫学 , 免疫学 , 造血

Research theme for competitive and other funds (5)：

2022 - 2025 高親和性抗体の産生及び持続をもたらす免疫応答の解明とワクチンへの応用
2021 - 2024 長期抗体産生を誘導する機能的NKT細胞の発生機序の解明
2019 - 2022 A role of bone marrow resident-uncommitted NKT cells under the infectious immune responses
2019 - 2022 新規肺炎球菌ワクチンのNKT細胞を介する抗体産生誘導及び感染防御の持続機構の解明
2017 - 2019 Molecular mechanisms of the CD69-Myl9 system in the chronic inflammation

Papers (17)：

Koji Hayashizaki, Yasuhiro Kamii, Yuki Kinjo. Glycolipid antigen recognition by invariant natural killer T cells and its role in homeostasis and antimicrobial responses. Frontiers in Immunology. 2024. 15
Yasuhiro Kamii, Koji Hayashizaki, Toshio Kanno, Akio Chiba, Taku Ikegami, Mitsuru Saito, Yukihiro Akeda, Toshiaki Ohteki, Masato Kubo, Kiyotsugu Yoshida, et al. IL-27 regulates the differentiation of follicular helper NKT cells via metabolic adaptation of mitochondria. Proceedings of the National Academy of Sciences. 2024. 121. 9
横山将也, 木村元子, 伊藤俊広, 林崎浩史, 遠藤将大, Wang Yangsong, 八木良二, 中川倫夫, 加藤直也, 松原久裕, et al. Myosin Light Chain 9/12と炎症性腸疾患の病態形成. 日本外科学会定期学術集会抄録集. 2022. 122回. SF-3
Toshio Kanno, Takahiro Nakajima, Yusuke Kawashima, Satoru Yokoyama, Hikari K. Asou, Shigemi Sasamoto, Koji Hayashizaki, Yuki Kinjo, Osamu Ohara, Toshinori Nakayama, et al. Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis. Cell Reports. 2021. 37. 6. 109921-109921
Toshio Kanno, Takahiro Nakajima, Satoru Yokoyama, Hikari K Asou, Shigemi Sasamoto, Yasuhiro Kamii, Koji Hayashizaki, Yasuo Ouchi, Taishi Onodera, Yoshimasa Takahashi, et al. SCD2-mediated monounsaturated fatty acid metabolism regulates cGAS-STING-dependent type I IFN responses in CD4+ T cells. Communications biology. 2021. 4. 1. 820-820

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MISC (6)：

林﨑浩史, 金城雄樹. iNKT細胞による感染防御. 臨床免疫・アレルギー科. 2023. 第80. 第3号. 305-310
上井康寛, 上井康寛, 上井康寛, 林崎浩史, 戸田尚子, 千葉明生, 杉本真也, 林崎浩史, 戸田尚子, 千葉明生, et al. Mechanisms of effector natural killer T cell differentiation by a novel pneumococcal vaccine. 東京慈恵会医科大学雑誌. 2022. 137. 6. 134-135
林﨑浩史, 上井康寛, 桑野和善, 金城雄樹. 肺炎球菌性肺炎の病態について. 呼吸器内科. 2021. 39. 6. 483-488
木村元子, 林﨑浩史, 中山俊憲. A new therapeutic target : CD69-Myl9 system regulates airway inflammation. 臨床免疫・アレルギー科 = Clinical immunology & allergology. 2018. 70. 4. 393-399
木村元子, 林﨑浩史, 中山俊憲. CD69-Myl9 system regulates allergic airway inflammation. 医学のあゆみ. 2018. 265. 9. 719-723

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Patents (2)：

Professional career (1)：

Work history (5)：

Awards (2)：

2021/12 - The 3rd Asian Pneumococcal Symposium Best Poster Award
2017/12 - Best Presentation Award Myosin light chains 9 and 12 are functional ligands for CD69 that regulate airway inflammation

Association Membership(s) (3)：

日本生体防御学会 , Japanese Society for Bacteriology , THE JAPANESE SOCIETY FOR IMMUNOLOGY

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