Yasuda Daisuke

ヤスダダイスケ | Yasuda Daisuke

Affiliation and department：

Research field (3)： Pathobiochemistry , Medical biochemistry , Experimental pathology

Research keywords (4)： Intracellular signaling , Angiogenesis , G protein-coupled receptor , lysophosphatidic acid

Research theme for competitive and other funds (17)：

2022 - 2025 生理活性脂質リゾホスファチジン酸によるリンパ管新生の分子機構と病態制御機能
2024 - 2025 生理活性リゾリン脂質が制御するリンパ管関連病態の治療の基盤研究
2023 - 2024 生理活性脂質リゾホスファチジン酸がリンパ管関連病態を制御するメカニズムの解明
2019 - 2022 G12/13-dependent signaling of bioactive lipid receptors that regulate PPARgamma activity in adipocytes
2019 - 2022 Mechanisms of cancer progression control mediated by LPA-induced YAP activation

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Papers (23)：

Daisuke Yasuda, Fumie Hamano, Kazuyuki Masuda, Märta Dahlström, Daiki Kobayashi, Nana Sato, Takao Hamakubo, Takao Shimizu, Satoshi Ishii. Inverse agonism of lysophospholipids with cationic head groups at Gi-coupled receptor GPR82. European journal of pharmacology. 2023. 954. 175893-175893
Keisuke Yanagida, Kayo Masago, Daisuke Yasuda, Fumie Hamano, Yoshitaka Kurikawa, Takao Shimizu, Satoshi Ishii. Cell-trafficking impairment in disease-associated LPA6 missense mutants and a potential pharmacoperone therapy for autosomal recessive woolly hair/hypotrichosis. Human Molecular Genetics. 2022
Samantha A. Spencer, Edna Suárez-Pozos, Jazmín Soto Verdugo, Huiqun Wang, Fatemah S. Afshari, Li Guo, Susmita Manam, Daisuke Yasuda, Arturo Ortega, James A. Lister, et al. Lysophosphatidic acid signaling via LPA ₆ : a negative modulator of developmental oligodendrocyte maturation. Journal of Neurochemistry. 2022
Yasuda D, Kobayashi D, Akahoshi N, Ohto-Nakanishi T, Yoshioka K, Takuwa Y, Mizuno S, Takahashi S, Ishii S. Lysophosphatidic acid-induced YAP/TAZ activation promotes developmental angiogenesis by repressing Notch ligand Dll4. The Journal of Clinical Investigation. 2019. 130. 10. 4332-4349
Yanagida K, Igarashi H, Yasuda D, Kobayashi D, Ohto-Nakanishi T, Akahoshi N, Sekiba A, Toyoda T, Ishijima T, Nakai Y, et al. The Gα12/13-coupled receptor LPA4 limits proper adipose tissue expansion and remodeling in diet-induced obesity. JCI insight. 2018. 3. 24

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MISC (4)：

Lectures and oral presentations (16)：

生理活性脂質リゾホスファチジン酸が促す血管・リンパ管新生の分子メカニズム
(第96回日本生化学会大会 2023)
血管・リンパ管新生を制御するリゾリン脂質の分子メカニズム
(CVMW2022 心血管代謝週間 2022)
リゾホスファチジン酸によるリンパ管新生の分子機構
(第95回日本生化学会 2022)
転写共役因子YAP/TAZを介したリゾホスファチジン酸の血管新生制御機構
(第92回日本生化学会大会 2019)
Gα12/13-coupled LPA receptors play an important role in developmental angiogenesis
(ICBL 2019 -60th International Conference on the Bioscience of Lipids- 2019)

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Education (2)：

Professional career (1)：

Work history (3)：

Awards (5)：

Association Membership(s) (3)：

THE JAPANESE CONFERENCE ON THE BIOCHEMISTRY OF LIPIDS , THE JAPANESE BIOCHEMICAL SOCIETY , 日本分子生物学会

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