Rchr
J-GLOBAL ID：201801016325894310   Update date: Sep. 11, 2024

Shichino Shigeyuki

シチノ シゲユキ | Shichino Shigeyuki
Affiliation and department：
Tokyo University of Science Organization for Research Advancement, Research Institute for Biomedical Sciences, Research Division

About Tokyo University of Science Organization for Research Advancement, Research Institute for Biomedical Sciences, Research Division


Job title： Assistant professor
Research field  (5)： Systems genomics ,  Tumor biology ,  Molecular biology ,  Genomics ,  Experimental pathology
Research keywords  (9)： fibrosis, murine model, single-cell RNA-seq ,  Transcroptome, single-cell, interactome network ,  fibrosis ,  シングルセルオミクス解析 ,  がん ,  バイオインフォマティクス ,  オミクス解析 ,  呼吸器疾患 ,  免疫・炎症
Research theme for competitive and other funds  (11)：
  • 2023 - 2026 Generation of pneumoconiosis atlas unraveling at 1-cell resolution
  • 2023 - 2026 Developing a pneumoconiosis atlas at the single-cell resolution
  • 2022 - 2025 Establishment of interstitial literacy based on complex systems crosstalk
  • 2022 - 2025 Investigation of the roles of stromal cell interactions in lung-bone marrow crosstalk
  • 2020 - 2023 増殖の臓器指向性と一細胞遺伝子発現解析に基づく治療最適抗腫瘍T細胞クローンの同定
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Papers (74)：
  • Yoshitaka Taketomi, Takayoshi Higashi, Kuniyuki Kano, Yoshimi Miki, Chika Mochizuki, Shota Toyoshima, Yoshimichi Okayama, Yasumasa Nishito, Susumu Nakae, Satoshi Tanaka, et al. Lipid-orchestrated paracrine circuit coordinates mast cell maturation and anaphylaxis through functional interaction with fibroblasts. Immunity. 2024
  • Miho Kurokawa, Takeshi Goya, Motoyuki Kohjima, Masatake Tanaka, Sadahiro Iwabuchi, Shigeyuki Shichino, Satoshi Ueha, Tomonobu Hioki, Tomomi Aoyagi, Motoi Takahashi, et al. Microcirculatory disturbance in acute liver injury is triggered by IFNγ-CD40 axis. Journal of inflammation (London, England). 2024. 21. 1. 23-23
  • Takatoshi Enomoto, Yuya Shirai, Yoshito Takeda, Ryuya Edahiro, Shigeyuki Shichino, Mana Nakayama, Miho Takahashi-Itoh, Yoshimi Noda, Yuichi Adachi, Takahiro Kawasaki, et al. SFTPB in serum extracellular vesicles as a biomarker of progressive pulmonary fibrosis. JCI insight. 2024. 9. 11
  • Ayaka Iwata, Juri Maruyama, Shibata Natsuki, Akira Nishiyama, Tomohiko Tamura, Minoru Tanaka, Shigeyuki Shichino, Takao Seki, Toshihiko Komai, Tomohisa Okamura, et al. Egr2 drives the differentiation of Ly6Chi monocytes into fibrosis-promoting macrophages in metabolic dysfunction-associated steatohepatitis in mice. Communications biology. 2024. 7. 1. 681-681
  • Hiroyasu Aoki, Masahiro Kitabatake, Haruka Abe, Peng Xu, Mikiya Tsunoda, Shigeyuki Shichino, Atsushi Hara, Noriko Ouji-Sageshima, Chihiro Motozono, Toshihiro Ito, et al. CD8+ T cell memory induced by successive SARS-CoV-2 mRNA vaccinations is characterized by shifts in clonal dominance. Cell reports. 2024. 43. 3. 113887-113887
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MISC (9)：
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Patents (13)：
  • 固相担体を用いた核酸増幅方法
  • 固相担体を用いた核酸増幅方法
  • 固相担体を用いた核酸増幅方法
  • 固相担体を用いた核酸増幅方法
  • 固相担体を用いた核酸増幅方法
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Books (9)：
  • 実験デザインからわかる シングルセル研究実践テキスト
    羊土社 2024
  • 一細胞から観た肺線維症をもたらす炎症細胞社会(Medical Science Digest)
    ニュー・サイエンス社 2022
  • シングルセル・オミックスの解析の発展(炎症と免疫)
    先端医学社 2022
  • 1細胞遺伝子発現解析をはじめとする1細胞オミックス技術の進歩とマクロファージ研究への応用 (シン・マクロファージ あらゆる疾患を制御する機能的多様性)
    羊土社 2022
  • 1細胞遺伝子発現解析をはじめとする1細胞オミックス技術の進歩と現状, The Lipid
    メディカルレビュー社 2021
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Lectures and oral presentations  (75)：
  • Investigation of the pathophysiology of lung fibrosis by a highly-sensitive single-cell RNA-seq methods TAS-Seq
    (第97回日本薬理学会年会 2023)
  • シングルセル解析技術開発と肺疾患・がん免疫応答研究への応用
    (第1回東京理科大学 血液がん・免疫・数理融合研究シンポジウム 2023)
  • 高汎用性・高感度cDNA 増幅法TAS-Seq2 の開発と病態研究への応用
    (NGS EXPO 2023 2023)
  • 腫瘍所属リンパ節で増殖する腫瘍反応性T細胞クローンの抗腫瘍応答への寄与
    (第27回日本がん免疫学会総会 2023)
  • CD8+ T cell clones maintain a pool of memory-like Ly108+ cells in the tumour during their contraction phase
    (第27回日本がん免疫学会総会 2023)
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Education (3)：
  • - 2018 The University of Tokyo Graduate School of Medicine, Division of Molecular Preventive Medicine
  • - 2018 The University of Tokyo Graduate School, Division of Medical Science
  • - 2012 The University of Tokyo Faculty of Pharmaceutical Science
Work history (4)：
  • 2018 - 現在 Organization for Research Advancement, Tokyo University of Science Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences Assistant professor
  • 2012 - 2018 Graduate School of Medicine, The University of Tokyo Department of Molecular Preventive Medicine Graduate Student
  • 2010 - 2012 The University of Tokyo Faculty of Pharmaceutical Sciences
  • 2008 - 2010 東京大学理科II類
Committee career (1)：
  • 2022/04/01 - 2023/03/31 日本免疫学会 免疫若手アカデミー会員
Awards (4)：
  • 2017/06 - 若手優秀演題賞
  • 2017/02 - ベストプレゼンテーション賞
  • 2016/01 - 若手優秀発表賞
  • 2014 - The 22nd International Symposium on Molecular Cell Biology of Macrophages Young Investigator Awards Inflammatory monocytes regulate tissue cell turnover and fibrosis diffusion in silica-induced pulmonary fibrosis in mice
Association Membership(s) (2)：
Japanese Society of Immunology ,  日本炎症・再生医学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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