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J-GLOBAL ID:201801016486661404   Update date: Aug. 26, 2024

Totoki Yasushi

トトキ ヤスシ | Totoki Yasushi
Affiliation and department:
Research field  (1): Genomics
Research keywords  (7): ゲノム医科学 ,  ゲノム科学 ,  Cancer Genomics ,  Cancer Genome ,  Bioinformatics ,  Cancer ,  Genome
Research theme for competitive and other funds  (4):
  • 2024 - 2027 胆道癌の日本人特有な変異原と発癌要因の解明
  • 2014 - 2017 Whole transcriptome analysis and novel therapeutic targets in biliary tract cancer
  • 2013 - 2016 Identification of novel fusion genes in gastric cancer by whole transcriptome sequencing: Discovery of potential therapeutic targets for gastric cancer
  • 2010 - 2012 Studies on cancer genomics to develop personalized therapy and medicine in breast cancer: Whole exome sequencing analysis of primary breast cancer and its metastatic tumor.
Papers (108):
  • Hirofumi Rokutan, Yasuhito Arai, Akiko Kunita, Satoshi Yamasaki, Hiromi Nakamura, Natsuko Hama, Atsuhito Nakayama, Fumie Hosoda, Yasushi Totoki, Mitsuhiro Fujishiro, et al. Genomic and Pathologic Profiling of Very Well-Differentiated Gastric Adenocarcinoma of Intestinal Type: A Study With Emphasis on Diffuse-Type Transformation. The American journal of surgical pathology. 2024. 48. 6. 652-661
  • Akihiko Fukagawa, Natsuko Hama, Yasushi Totoki, Hiromi Nakamura, Yasuhito Arai, Mihoko Saito-Adachi, Akiko Maeshima, Yoshiyuki Matsui, Shinichi Yachida, Tetsuo Ushiku, et al. Genomic and epigenomic integrative subtypes of renal cell carcinoma in a Japanese cohort. Nature Communications. 2023. 14. 1
  • Mihoko Saito-Adachi, Natsuko Hama, Yasushi Totoki, Hiromi Nakamura, Yasuhito Arai, Fumie Hosoda, Hirofumi Rokutan, Shinichi Yachida, Mamoru Kato, Akihiko Fukagawa, et al. Oncogenic structural aberration landscape in gastric cancer genomes. Nature communications. 2023. 14. 1. 3688-3688
  • Hiroyuki Abe, Hirofumi Rokutan, Yasushi Totoki, Hiromi Nakamura, Tatsuhiro Shibata, Tetsuo Ushiku, Masashi Fukayama. Lost expression of AT-rich interaction domain 1A in the gastric mucosa-A constituent of field cancerization in the stomach. Pathology international. 2023. 73. 6. 234-245
  • Yasushi Totoki, Mihoko Saito-Adachi, Yuichi Shiraishi, Daisuke Komura, Hiromi Nakamura, Akihiro Suzuki, Kenji Tatsuno, Hirofumi Rokutan, Natsuko Hama, Shogo Yamamoto, et al. Multiancestry genomic and transcriptomic analysis of gastric cancer. Nature genetics. 2023. 55. 4. 581-594
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MISC (157):
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Books (8):
  • がんゲノムペディア : 77のキーワードで理解するゲノム医療とゲノム研究
    羊土社 2024 ISBN:9784758121309
  • 実験医学 「特集 クローン進化 病の起源を探る」
    羊土社 2023 ISBN:9784758125666
  • 肝胆膵「特集 肝胆膵疾患のエピジェネティクスを学ぶ」
    アークメディア 2018
  • 遺伝子医学「オミックスで加速するがんバイオマーカー研究の最新動向」
    メディカルドゥ 2015 ISBN:9784944157594
  • 実験医学「個別化医療を拓くがんゲノム研究」
    羊土社 2014 ISBN:9784758103404
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Education (3):
  • 2018 - 2022 The University of Tokyo Graduate School of Medicine
  • 1985 - 1987 Nagoya University School of Science Department of Physics
  • 1983 - 1985 Nagoya University School of Science
Professional career (1):
  • Ph.D. (The University of Tokyo)
Work history (7):
  • 2023/05 - 現在 Osaka University
  • 2023/04 - 2023/04 国立がん研究センター 研究所 臨床ゲノム解析部門 非常勤研究員
  • 2010/11 - 2023/03 国立がん研究センター 研究所 がんゲノミクス研究分野 ユニット長
  • 2008/08 - 2010/10 国立がん研究センター 研究所 ゲノム構造解析プロジェクト 主任研究員
  • 2008/04 - 2008/07 理化学研究所 基幹研究所 先端計算機科学領域 副チームリーダー
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