Takahashi Hiroki

Affiliation and department：

Research field (1)： Bacteriology

Research theme for competitive and other funds (8)：

2022 - 2028 Platform for Advanced Genome Science
2021 - 2025 前例の無い大規模探索によるマイコウイルス学の創生と糸状菌育種への挑戦
2021 - 2024 Whole-genome analysis for drug-resistance and pathogenicity of Aspergillus fumigatus
2016 - 2021 先進ゲノム解析研究推進プラットフォーム
2016 - 2019 Investigation of transcriptome responses upon exposure to diverse environmental changes in Aspergillus fumigatus

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Papers (107)：

Saho Shibata, Momotaka Uchida, Sayaka Ban, Katsuhiko Kamei, Akira Watanabe, Takashi Yaguchi, Vit Hubka, Hiroki Takahashi. Discovery of allodiploid hybrid speciesAspergillus latusin Japan. 2024
Yuriko Yamazaki, Tomoka Ito, Seitaro Nakagawa, Takashi Sugihira, Chinami Kurita-Tachibana, Amer E. Villaruz, Kensuke Ishiguro, Barbora Salcman, Shuo Li, Sanami Takada, et al. Altered genomic methylation promotes Staphylococcus aureus persistence in hospital environment. Nature Communications. 2024. 15. 1
Noriko Takeuchi, Misako Ohkusu, Yoko Kusuya, Hiroki Takahashi, Masashi Yamaguchi, Yuko Omata, Tomoko Nakazawa, Naruhiko Ishiwada. Comparative genomic and morphological analyses of capsular and capsular-deficient pneumococcal strains simultaneously isolated from a patient with invasive pneumococcal disease. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2024
Reika Aoyama, Seitaro Nakagawa, Yoko Ichikawa, Naohiro Inohara, Yuriko Yamazaki, Tomoka Ito, Takashi Sugihira, Michihiro Kono, Masashi Akiyama, Hiroki Takahashi, et al. Neonatal skin dysbiosis to infantile atopic dermatitis: Mitigating effects of skin care. Allergy. 2024. 79. 6. 1618-1622
Xiaohui He, Yoko Kusuya, Daisuke Hagiwara, Takahito Toyotome, Teppei Arai, Cai Bian, Masaki Nagayama, Saho Shibata, Akira Watanabe, Hiroki Takahashi. Genomic diversity of the pathogenic fungus Aspergillus fumigatus in Japan reveals the complex genomic basis of azole resistance. Communications Biology. 2024. 7. 1

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MISC (41)：

藤田理紗, 足立夕佳, 関口哲志, 庄子習一, 古谷正裕, 谷井孝至, 田中大器, 石原潤一, 高橋弘喜. Consideration of Microfluidic Devices for Improving Single-Cell Encapsulation Efficiency in Microdroplets. センサ・マイクロマシンと応用システムシンポジウム(CD-ROM). 2023. 40th
山中夏樹, 山口隼平, 高橋弘喜, 高橋弘喜, 原康雅, 原康雅, 石橋正己, 石橋正己, 高屋明子, 高屋明子, et al. The alternative mechanism of carbapenem tolerance in non-carbapenemase-producing Klebsiella. 日本薬学会年会要旨集(Web). 2023. 143rd
馬目照久, 中村文香, 原康雅, 原康雅, 高屋明子, 高屋明子, 高屋明子, 伴さやか, 高橋弘喜, 高橋弘喜, et al. Search for new natural products from Nocardia carnea IFM 12324 and biosynthetic gene analysis for an isolated compound. 日本薬学会年会要旨集(Web). 2023. 143rd
松岡悠美, 高橋弘喜, 高屋明子. Development of novel therapeutic approach for systemic persister infections. 千葉大学真菌医学研究センター報告. 2023. 26
高屋明子, 高屋明子, 常世田好司, 松岡悠美, 高橋弘喜, 根本哲宏. 新規抗菌薬開発の基盤となる細菌パーシスター制御化合物創出に向けた取り組み. 日本感染症学会総会・学術講演会・日本化学療法学会学術集会合同学会プログラム・抄録集(CD-ROM). 2023. 97th-71st

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Patents (1)：

アトピー性皮膚炎の発症リスク判定方法、バイオマーカー、予防薬または治療薬のスクリーニング方法

Books (2)：

独習Pythonバイオ情報解析 : Jupyter、NumPy、pandas、Matplotlibを理解し、実装して学ぶシングルセル、RNA-Seqデータ解析
羊土社 2021 ISBN:9784758122498
化学療法の領域
医薬ジャーナル社 2017

Lectures and oral presentations (28)：

微生物ゲノム研究法の進展とその応用
(第121回日本皮膚科学会総会 2022)
病原真菌アスペルギルスフミガタスの遺伝型解析
(第199回酵母細胞研究会例会 2021)
微生物統合データベース MicrobeDB.jp version 3
(第14回日本ゲノム微生物学会年会)
Investigation of of adaptation to hypoxia in Aspergillus fumigatus
(9th Advances Against Aspergillosis and Mucormycosis 2020)
Investigation of the molecular mechanisms of copper homeostasis in Aspergillus fumigatus
(9th Advances Against Aspergillosis and Mucormycosis 2020)

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Professional career (1)：

Doctor of Science (Nara Institute of Science and Technology)

Awards (2)：

2020 - 第64回日本医真菌学会総会・学術集会最優秀演題賞 Aspergillus fumigatus のアゾール耐性に関わる新規因子について
2018/02 - JNM・生薬学雑誌論文賞 De novo transcriptome assembly and characterization of nine tissues of Lonicera japonica to identify potential candidate genes involved in chlorogenic acid, luteolosides, and secoiridoid biosynthesis pathways

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