Rchr
J-GLOBAL ID:201801016950036755
Update date: Sep. 21, 2024
Honma Teruki
ホンマ テルキ | Honma Teruki
Affiliation and department:
Job title:
チームリーダー
Research field (1):
Pharmaceuticals - chemistry and drug development
Research theme for competitive and other funds (3):
- 2015 - 2018 Development of super-resolution structure analysis techniques for bio-macromolecules based on a quantum chemical calculation
- 2014 - 2016 Pyrimidine biosynthesis and energy metabolism in cancer microenvironment
- 2010 - 2015 Structural analysis of HLA class I/II molecules
Papers (99):
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Yosuke Nishigaya, Shohei Takase, Tatsunobu Sumiya, Tomohiro Sato, Hideaki Niwa, Shin Sato, Akiko Nakata, Seiji Matsuoka, Yuki Maemoto, Noriaki Hashimoto, et al. Structure-based development of novel substrate-type G9a inhibitors as epigenetic modulators for sickle cell disease treatment. Bioorganic & medicinal chemistry letters. 2024. 110. 129856-129856
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Koji Okuwaki, Naoki Watanabe, Koichiro Kato, Chiduru Watanabe, Naofumi Nakayama, Akifumi Kato, Yuji Mochizuki, Tatsuya Nakano, Teruki Honma, Kaori Fukuzawa. Geometry Optimization using the Frozen Domain and Partial Dimer Approach with the Fragment Molecular Orbital Method: Implementation, Benchmark, and Application for Ligand-Binding Site of Proteins. 2024
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Kikuko Kamisaka, Shunpei Nagase, Chiduru Watanabe, Daisuke Takaya, Hitomi Yuki, Teruki Honma. Statistical analysis of interactions among amino acid residues in apo structures using fragment molecular orbital method. Chem-Bio Informatics Journal. 2024. 24. 25-47
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Yuya Seki, Chiduru Watanabe, Norihiko Tani, Kikuko Kamisaka, Tatsuya Ohyama, Daisuke Takaya, Teruki Honma. Structural Stability and Binding Ability of SARS-CoV-2 Main Protease with GC376: A Stereoisomeric Covalent Ligand Analysis by FMO calculation. Chem-Bio Informatics Journal. 2024. 24. 13-24
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Hirotomo Moriwaki, Yusuke Kawashima, Chiduru Watanabe, Kikuko Kamisaka, Yoshio Okiyama, Kaori Fukuzawa, Teruki Honma. FMOe: Preprocessing and visualizing package of the fragment molecular orbital method for Molecular Operating Environment and its applications in covalent ligand and metalloprotein analyses. 2024
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MISC (74):
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小田島大貴, 宮川柊兵, 半田佑磨, 古石誉之, 米持悦生, 佐藤朋広, 幸瞳, 本間光貴, 高谷大輔, 上村みどり, et al. Study of novel inhibitors of m-Glu5 using fragment molecular orbital method. 日本薬学会年会要旨集(Web). 2024. 144th
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小田島大貴, 宮川柊兵, 半田佑磨, 古石誉之, 米持悦生, 佐藤朋広, 幸瞳, 本間光貴, 高谷大輔, 上村みどり, et al. フラグメント分子軌道法を活用した代謝型グルタミン酸受容体5阻害剤の分子設計. 構造活性相関シンポジウム講演要旨集(CD-ROM). 2023. 51st
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渡邉千鶴, 渡邉千鶴, 神坂紀久子, 今井恭平, 滝本大地, 斎藤涼祐, 栗田典之, 岡山友樹, 宮嶋起徳, 吉本耀, et al. FMODBデータ収集:高分解能X線結晶構造データに対する量子化学計算. 日本蛋白質科学会年会プログラム・要旨集. 2022. 22nd (Web)
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渡邉千鶴, 田中成典, 沖山佳生, 大山達也, 神坂紀久子, 幸瞳, 高谷大輔, 福澤薫, 本間光貴. FMO法を用いたSARS-CoV-2メインプロテアーゼ-阻害薬S-217622結合メカニズムの解明. 構造活性相関シンポジウム講演要旨集. 2022. 50th (CD-ROM)
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渡邉一樹, 渡邉一樹, 渡邉千鶴, 渡邉千鶴, 本間光貴, 田雨時, 川嶋裕介, 川下理日人, 星野忠次, 西田紀貴, et al. FMO計算によるSARS-CoV-2変異株RBD-中和抗体間の相互作用解析. 日本薬学会関東支部大会講演要旨集. 2021. 65th
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Patents (13):
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