Akiba Hiroki

Affiliation and department：
Job title： Assistant Professor
Other affiliations (1)：

Research field (4)： Biophysics , Applied biofunctional and bioprocess engineering , Biochemistry , Pharmaceuticals - chemistry and drug development

Research theme for competitive and other funds (3)：

Papers (36)：

Hiroki Akiba, Junso Fujita, Tomoko Ise, Kentaro Nishiyama, Tomoko Miyata, Takayuki Kato, Keiichi Namba, Hiroaki Ohno, Haruhiko Kamada, Satoshi Nagata, et al. Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection. Communications Biology. 2023. 6. 1. 987
Kentaro Nishiyama, Hiroki Akiba, Satoshi Nagata, Kouhei Tsumoto, Haruhiko Kamada, Hiroaki Ohno. A Proximity-Induced Fluorogenic Reaction Triggered by Antibody-Antigen Interactions with Adjacent Epitopes. Angewandte Chemie International Edition. 2023. 62. 30
Rika A. Furuta, Teruhito Yasui, Takeharu Minamitani, Hiroki Akiba, Chizu Toyoda, Ryutaro Tobita, Kazuta Yasui, Ryota Aminaka, Mikako Masaki, Masahiro Satake. Development of a recombinant hepatitis B immunoglobulin derived from B cells collected from healthy individuals administered with hepatitis B virus vaccines: A feasibility study. Transfusion. 2023. 63. 6. 1204-1214
Hiroki Akiba, Hiroko Tamura, Jose M M Caaveiro, Kouhei Tsumoto. Epitope-dependent thermodynamic signature of single-domain antibodies against hen egg lysozyme. The Journal of Biochemistry. 2021. 170. 5. 623-629
Toshihiro Ito, Takeharu Minamitani, Masaki Hayakawa, Ryota Otsubo, Hiroki Akiba, Kouhei Tsumoto, Masanori Matsumoto, Teruhito Yasui. Optimization of anti-ADAMTS13 antibodies for the treatment of ADAMTS13-related bleeding disorder in patients receiving circulatory assist device support. Scientific Reports. 2021. 11. 22341

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MISC (3)：

由井杏奈, 菊池智佳, 郷田秀一郎, 工藤翔太, 秋葉宏樹, 中木戸誠, 黒田大祐, 黒田大祐, 長門石曉, 長門石曉, et al. がん転移に関するLI-cadherin一塩基多型の分子メカニズム. 日本生化学会大会(Web). 2019. 92nd
由井杏奈, 菊池智佳, 工藤翔太, 秋葉宏樹, 中木戸誠, 長門石曉, 長門石曉, 新井修, 岩成宏子, 浜窪隆雄, et al. LI-cadherinの一変異が大腸がんのリンパ節転移に与える影響. 日本がん転移学会学術集会・総会プログラム抄録集. 2018. 27th
K. Fujiwara, K. Koyama, K. Suga, M. Takahashi, O. Kusano-Arai, K. Mitsui, H. Akiba, H. Iwanari, K. Tsumoto, T. Hamakubo, et al. Imaging of CDH17-positive gastric cancer xenografts with 64Cu-labeled anti-CDH17 IgG PET. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2015. 42. S420-S420

Patents (1)：

Lectures and oral presentations (1)：

Education (5)：

2010 - 2013 The University of Tokyo School of Engineering Department of Advanced Interdisciplinary Studies
2008 - 2010 The University of Tokyo School of Engineering Department of Chemistry and Biotechnology
2006 - 2008 The University of Tokyo Faculty of Engineering Department of Chemistry and Biotechnology
2004 - 2006 The University of Tokyo College of Arts and Sciences
2001 - 2004 静岡県立富士高等学校

Work history (6)：

2020/01 - 現在 National Institutes of Biomedical Innovation, Health and Nutrition Center for Drug Design Research Research Scientist
2020/01 - 現在 Kyoto University Graduate School of Pharmaceutical Sciences Assistant Professor
2022/04 - 2023/03 National Institutes of Biomedical Innovation, Health and Nutrition
2016/10 - 2019/12 National Institutes of Biomedical Innovation, Health and Nutrition Center for Drug Design Research Project Researcher
2016/04 - 2016/10 The University of Tokyo School of Engineering Project Researcher

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Committee career (2)：

Awards (4)：

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