2020 - 2022 Development of fail-safe system for human iPSC-derived tumor by CAR-T cell therapyCAR-T cell therapy
2019 - 2022 Functional analysis of novel immune checkpoints and development of combined immunotherapy in gynecological cancer
2019 - 2022 Development of TIL culture method for tumor infiltrating T cell therapy for cervical cancer
2018 - 2021 Evaluation of the role of beta-catenin pathway in human melanoma in anti-cancer immune responses
2019 - 2020 脂質代謝経路を標的としたがん免疫療法の探索
2015 - 2018 Development of a novel molecular targeted therapy against acral melanomas
2015 - 2018 Identification of the sub-population in human malignant melanoma showing strong resistance to tumor specific cytotoxic T cells
2013 - 2016 Investigating cancer-immunoescape mechanism and effective immuunotherapy for ovarian cancer
2013 - 2015 Systematic analysis of cellular signaling involved in the melanoma induced immunosuppression
2012 - 2015 Expression and Functional Analysis of HOXD9 in Cervical Cancer
2012 - 2015 Elucidation of the condition of construction mechanisms of immunity on sentinel lymph nodes of patients with melanoma and development of novel immunotherapy
2013 - 2015 Enhancement of anti-tumor immune responses by EGFR-TKIs (EGFR- tyrosin kinase inhibitors)
2011 - 2014 Development of effective immunotherapy by combining interventions on key points in the anti-tumor immune network
2011 - 2012 Investigation of roles of miRNA in the immunosuppression and clinical use for patients with melanoma
2011 - 2012 The role of Histatin-1 ectopically expressed in human melanoma cells
2009 - 2010 Elucidation of the mechanism of immunosuppression by mesenchymal stem cells in cancer microenvironments
2008 - 2009 癌シグナル伝達異常による、消化器癌の免疫逃避機構の解明と克服法の開発
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Papers (78)：
Toshihiro Sugi, Yuki Katoh, Toshikatsu Ikeda, Daichi Seta, Takashi Iwata, Hiroshi Nishio, Masaki Sugawara, Daiki Kato, Kanoko Katoh, Kei Kawana, et al. SCD1 inhibition enhances the effector functions of CD8+ T cells via ACAT1-dependent reduction of esterified cholesterol. Cancer science. 2023
片桐 楓汀, 西尾 浩, 香川 昌紀, 今川 遼太郎, 佐々木 千代美, 村木 智子, 菅原 正貴, 松田 理沙, 杉山 重里, 岩田 卓, et al. HNF1betaを治療標的とした卵巣明細胞癌における新規複合的免疫療法の確立(Establishment of novel combination mmunotherapy by targeting HNF-1beta in ovarian clear cell carcinoma). 日本癌学会総会記事. 2023. 82回. 1164-1164
Yuki Katoh, Tomonori Yaguchi, Akiko Kubo, Takashi Iwata, Kenji Morii, Daiki Kato, Shigeki Ohta, Ryosuke Satomi, Yasuhiro Yamamoto, Yoshitaka Oyamada, et al. Inhibition of stearoyl-CoA desaturase 1 (SCD1) enhances the antitumor T cell response through regulating β-catenin signaling in cancer cells and ER stress in T cells and synergizes with anti-PD-1 antibody. Journal for immunotherapy of cancer. 2022. 10. 7
Keitaro Fukuda, Ken Okamura, Rebecca L. Riding, Xueli Fan, Khashayar Afshari, Nazgol-Sadat Haddadi, Sean M. McCauley, Mehmet H. Guney, Jeremy Luban, Takeru Funakoshi, et al. AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma. Journal of Experimental Medicine. 2021. 218. 9
Ikuko Hirai, Takeru Funakoshi, Hajime Kamijuku, Keitaro Fukuda, Mariko Mori, Masatoshi Sakurai, Yuya Koda, Jun Kato, Takehiko Mori, Naohide Watanabe, et al. Adoptive cell therapy using tumor-infiltrating lymphocytes for melanoma refractory to immune-checkpoint inhibitors. Cancer Science. 2021
2020/01 - 現在 Kyoto University Department of Immunology and Genomic Medicine, Graduate School of Medicine
2016/04 - 2019/12 Keio University School of Medicine Institute for Advanced Medical Research (Division of Cellular Signaling)
2009/04 - 2016/03 Keio University School of Medicine Institute for Advanced Medical Research (Division of Cellular Signaling)
2008/04 - 2009/03 日本学術振興会特別研究員(DC2)
2003/04 - 2005/04 慶應義塾大学病院 内科 研修医
Association Membership(s) (5)：
The Japanese Society of Internal Medicine
, The Japanese Society of Clinical Immunology
, Japanese Society for Immunology
, Japanese cancer association
, Japanese Association of Cancer Immunology
