Nakahata Shingo

ナカハタシンゴ | Nakahata Shingo

Affiliation and department：
Homepage URL (1)： http://www.med.miyazaki-u.ac.jp/home/biochem1/

Research field (1)： Pathobiochemistry

Research theme for competitive and other funds (16)：

2022 - 2025 Study on immune evasion strategy and mechanism of the promotion of carcinogenesis of HTLV-1-infected cells
2022 - 2025 Mechanism of Adult T-Cell Leukemia Development Dependent on Metabolic Aberration Caused by NDRG2 Deficiency
2021 - 2025 低侵襲・効率的な胎内サイトメガロウイルス感染症診断のための新たなアルゴリズム開発
2019 - 2022 Elucidation of the mechanism of adult T-cell leukemia (ATL) development based on gut microbiota analysis
2018 - 2021 Comparative analysis of tumorigenesis by HTLV-1 and BLV

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Papers (51)：

Yu Wang, Jiazhou Li, Shingo Nakahata, Hidekatsu Iha. Complex Role of Regulatory T Cells (Tregs) in the Tumor Microenvironment: Their Molecular Mechanisms and Bidirectional Effects on Cancer Progression. International journal of molecular sciences. 2024. 25. 13
Tomonaga Ichikawa, Akira Suekane, Shingo Nakahata, Hidekatsu Iha, Kazuya Shimoda, Takashi Murakami, Kazuhiro Morishita. Inhibition of PRMT5/MEP50 Arginine Methyltransferase Activity Causes Cancer Vulnerability in NDRG2low Adult T-Cell Leukemia/Lymphoma. International journal of molecular sciences. 2024. 25. 5
Kosuke Mochida, Shingo Nakahata, Yutaka Suzuki, Kentaro Inoue, Sayaka Moriguchi, Atsushi Yamashita, Masahiro Amano, Kazuhiro Morishita. Prognostic analysis of smoldering ATLL with skin eruptions based on genomic aberrations. Journal of Dermatological Science. 2023
Akira Suekane, Tomonaga Ichikawa, Yusuke Saito, Shingo Nakahata, Kazuhiro Morishita. The CGRP Receptor Antagonist MK0974 Induces EVI1high AML Cell Apoptosis by Disrupting ERK Signaling. Anticancer research. 2022. 42. 10. 4743-4752
Happy Kurnia Permatasari, Shingo Nakahata, Tomonaga Ichikawa, Yanuar Rahmat Fauzi, Hiroshi Kiyonari, Kotaro Shide, Takuro Kameda, Kazuya Shimoda, Masaya Ono, Tomohiko Taki, et al. Oncogenic isoform switch of tumor suppressor BCL11B in adult T-cell leukemia/lymphoma. Experimental Hematology. 2022. 111. 41-49

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MISC (4)：

中畑新吾, 下崎俊介, 市川朝永, 亀田拓郎, 日高智徳, 久冨木庸子, 黒澤仁, 下田和哉, 森下和広. トランスフェリン受容体抗体はモガムリズマブ治療難治性のATLLの増殖抑制に有効である(High efficacy of anti-TFR1 antibody against the growth of mogamulizmab-resistant ATLL cells). 臨床血液. 2018. 59. 9. 1719-1719
Shingo Nakahata, Kazuhiro Morishita. Novel roles for the tumor suppressor gene NDRG2 via the regulation of PTEN phosphorylation. Seikagaku. 2017. 89. 6. 877-880
I. Nishikata, S. Nakahata, Y. Saito, K. Kaneda, E. Ichihara, N. Yamakawa, K. Morishita. Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiation. ONCOGENE. 2011. 30. 40. 4194-4207
眞鍋香澄, 高松尚文, 日高智徳, 中畑新吾, 前田宏一, 濱崎誠, 岩田喬子, 鵜飼由範, 岡山昭彦, 坪内博仁, et al. 成人T細胞性白血病/リンパ腫(ATLL)に対するTSLC1/IgSF4抗体を用いた診断応用(Diagnostic application using TSLC1/IgSF4 antibodies to Adult T cell leukemia/lymphoma (ATLL)). 日本癌学会総会記事. 2009. 68回. 334-334

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