2015 - 2018 Creation of new genome science using chemical tools to precisely detect modification and damage of human genome
2014 - 2018 テロメアRNA四重鎖構造分子基盤の解明を目指したケミカルバイオロジー
2010 - 2015 Creation of genome manipulation technology using super restriction enzyme
2012 - 2014 クリックケミストリ-による癌細胞の革新的可視化技術の開発
2010 - 2012 化学的アプローチによる細胞中のヒトテロメア DNA と RNA 構造の解明およびその応用
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Papers (86):
RNA structure promotes liquid-to-solid phase transition of short RNAs in neuronal dysfunction. 2024. 7. 137
DNA and RNA G-quadruplexes in human telomere: Structures, properties, and applications. 2024. 29. 174
Shiyu Wang, Yi Song, Zhiyong He, Hisao Saneyoshi, Rie Iwakiri, Pengyu Xu, Chuanqi Zhao, Xiaogang Qu, Yan Xu. Unusual topological RNA G-quadruplex formed by an RNA duplex: implications for the dimerization of SARS-CoV-2 RNA. Chem. Commun. 2023. 59. 85. 12703-12706
Chao-Da Xiao, Meng-Hao Jia, Ming-Qing Zhong, Yan Xu, Zu-Tao Yu, Zhi-Yong He, Xu Lu, Yan Zhang, Xue Zhou, Lin-Yun Fu, et al. Unveiling the role of G-quadruplex structure in promoter region: Regulation of ABCA1 expression in macrophages possibly via NONO protein recruitment. International Journal of Biological Macromolecules. 2023. 245. 125443
Oligonucleotide containing 8-trifluoromethyl-2'-deoxy-guanosine as a Z-DNA probe. Method Mol. Biol. 2023. 2651. 115-130