Rchr
J-GLOBAL ID:201801017274232690
Update date: Nov. 15, 2024
Uzawa Akiyuki
ウザワ アキユキ | Uzawa Akiyuki
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Affiliation and department:
Chiba University Neurology
About Chiba University Neurology
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Detailed information
Research field (1):
Neurology
Research keywords (4):
Myasthenia gravis
, Neuromyelitis optica
, Multiple sclerosis
, Neuroimmunology
Research theme for competitive and other funds (9):
2022 - 2025 シングルセルRNA解析を用いた重症筋無力症の分子病態解明
2021 - 2023 標的抗原細胞外領域とIgG1Fc融合タンパク質による自己抗体病の革新的治療法開発
2019 - 2022 Elucidation of the action mechanism in vivo of AChR-Fc, a novel treatment for myasthenia gravis
2018 - 2021 Comprehensive search of autoantibies in neuroimmunological disorders using a novel hybrid SEREX-FACS method
2017 - 2019 Development of New treatment for myasthenia gravis targeting for HMGB1
2016 - 2019 Development of novel treatment against peroxiredoxin in central nervous system demyelinating diseases
2015 - 2018 Novel therapeutic strategies for multiple sclerosis targeting autoantibodies against talin.
2012 - 2014 High-mobility group box 1 is involved in neuromyelitis optica pathogensesis and could be a therapeutic target.
2010 - 2011 Development of mouse model of neuromyelitis optica induced by aquaporin-4 protein immunization
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Papers (227):
Manato Yasuda, Akiyuki Uzawa, Yosuke Onishi, Hideo Handa, Hiroyuki Akamine, Etsuko Ogaya, Yukiko Ozawa, Hiroki Masuda, Masahiro Mori, Satoshi Kuwabara. Elevated serum levels of C-terminal agrin fragment in acetylcholine receptor antibody-positive myasthenia gravis. Journal of neuroimmunology. 2024. 396. 578455-578455
Takamichi Sugimoto, Shigeaki Suzuki, Akiyuki Uzawa, Takemori Yamawaki, Masayuki Masuda, Naoya Minami, Naoki Kawaguchi, Tomoya Kubota, Masanori P Takahashi, Yasushi Suzuki, et al. Worsening of myasthenic symptoms associated with statins. Journal of the neurological sciences. 2024. 464. 123154-123154
Hideo Handa, Akiyuki Uzawa, Masahiro Mori, Manato Yasuda, Yosuke Onishi, Hiroyuki Akamine, Etsuko Ogaya, Yoko Niibe, Hajime Yokota, Satoshi Kuwabara. Effects of Denosumab and Bisphosphonates on Glucocorticoid-induced Osteoporosis in Patients with Neuroimmunological Disorders. Internal medicine (Tokyo, Japan). 2024
Shigeaki Suzuki, Akiyuki Uzawa, Yuriko Nagane, Masayuki Masuda, Shingo Konno, Tomoya Kubota, Makoto Samukawa, Kei Ishizuchi, Daiki Tokuyasu, Hideo Handa, et al. Therapeutic Responses to Efgartigimod for Generalized Myasthenia Gravis in Japan. Neurology. Clinical practice. 2024. 14. 3. e200276
Akiyuki Uzawa, Masahiro Mori, Hiroki Masuda, Mayumi Muto, Ryohei Ohtani, Shinji Aoyama, Kazuyuki Matsushita, Satoshi Kuwabara. Contributions of CSF interleukin-6 elevation to the pathogenesis of myelin oligodendrocyte glycoprotein antibody-associated disease. Multiple sclerosis (Houndmills, Basingstoke, England). 2024. 13524585241254731-13524585241254731
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MISC (251):
Uzawa Akiyuki, Samukawa Makoto, Konno Shingo, Mishiro Izumi, Taki Kentaro, Todaka Hiroshi, Shiraiwa Kunihiko, Ohashi Yohei. 重症筋無力症患者における早期速効性治療 レセプトデータを用いた研究(Early fast acting treatments in patients with myasthenia gravis: An insurance claims database study). 神経治療学. 2023. 40. 6. S243-S243
Konno Shingo, Uzawa Akiyuki, Samukawa Makoto, Todaka Hiroshi, Mishiro Izumi, Taki Kentaro, Shiraiwa Kunihiko, Ohashi Yohei. 日本人重症筋無力症患者での治療選択肢 保険金請求データベース研究(Treatment patterns among Japanese myasthenia gravis patients: An insurance claims database study). 神経免疫学. 2023. 28. 1. 232-232
赤嶺博行, 鵜沢顕之, 桑原聡, 大西庸介, 安田真人, 小澤由希子, 川口直樹, 久保田智哉, 高橋正紀, 鈴木重明, et al. 機械学習を用いた重症筋無力症のMinimal Manifestation診断モデルに関する研究. 神経治療学(Web). 2023. 40. 6
徳安大輝, 鈴木重明, 鵜沢顕之, 長根百合子, 増田眞之, 紺野晋吾, 久保田智哉, 寒川真, 杉本太路, 鈴木靖士, et al. 全身型重症筋無力症(MG)に対するエクリズマブ使用例の長期的観察:Japan MG registry study. Neuroimmunology. 2023. 28. 1
鋸屋悦子, 鵜沢顕之, 小澤由希子, 小澤由希子, 安田真人, 大西庸介, 赤嶺博行, 半田秀雄, 桑原聡. 重症筋無力症における経口デキサメタゾン療法の治療反応性. Neuroimmunology. 2023. 28. 1
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Lectures and oral presentations (2):
眼筋型重症筋無力症の全身化のリスク因子に関する解析
(臨床神経学 2021)
血清可溶性ウロキナーゼ受容体濃度は重症筋無力症の重症度スケールと相関する
(臨床神経学 2021)
Education (1):
2008 - 2012 千葉大学 大学院 医学薬学府 先端生命科学 博士課程
Professional career (1):
PhD (Chiba University)
Work history (7):
2021/09 - 現在 千葉大学医学部附属病院 脳神経内科 診療講師
2012/04 - 2021/08 千葉大学医学部附属病院 脳神経内科 助教
2008/10 - 2012/03 千葉大学医学部附属病院神経内科 医員
2007/10 - 2008/09 国保松戸市立病院神経内科
2006/04 - 2007/09 千葉労災病院神経内科
2005/04 - 2006/03 千葉市立青葉病院内科
2003/04 - 2005/03 千葉大学医学部附属病院神経内科
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Committee career (1):
重症筋無力症/ランバート・イートン筋無力症候群診療ガイドライン作成委員
Awards (11):
2022/11 - 日本神経治療学会 優秀演題賞
2022/11 - 日本神経治療学会 学会賞(治療学術賞)
2022/10 - 日本神経免疫学会 創世賞
2018/05 - 日本神経学会 最優秀口演賞
2017 - International Taiwanese Congress of Neurology, Travel Award
2016 - 全国筋無力症友の会 重症筋無力症治療研究奨励賞
2012 - 千葉大学医学薬学府長表彰
2012 - 千葉大学学長表彰
2012 - Asian Oceanian Congress of Neurology, Young Investigator Award
2011 - 日本多発性硬化症協会 研究助成賞
2009 - 千葉医学会 奨励賞
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Association Membership(s) (6):
JAPAN EPILEPSY SOCIETY
, 日本神経治療学会
, THE JAPAN STROKE SOCIETY
, THE JAPANESE SOCIETY OF INTERNAL MEDICINE
, 日本神経免疫学会
, JAPANESE SOCIETY OF NEUROLOGY
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