Iwasaki Kengo

イワサキケンゴ | Iwasaki Kengo

Research field (1)： Conservative dentistry and endodontics

Research theme for competitive and other funds (22)：

2024 - 2027 Novel periodontal tissue regeneration treatment based on cell-free treatment using stem cell extracts.
2024 - 2027 血管内皮チューブ構造を有するiPS細胞由来マイクロスフェロイドを用いた歯周組織再生
2021 - 2024 Novel strategy for periodontal tissue regeneraion using dead cell-derived signals
2020 - 2023 ゼノフリーiPS細胞由来幹細胞の三次元細胞構造体が拓く骨再生医療
2020 - 2023 Positional HOX signatureに基づく歯周組織の診断と再生戦略

2018 - 2021 Novel strategy for periodontal regeneration using interactions between mesenchymal stem cells and endothelial cells

2015 - 2019 Effects of stem cell-derived exosomes on periodontal regeneration

2015 - 2019 A new strategy of bone metabolism activation to promote tooth movement: Nanoparticle-based DDS approach

2015 - 2018 Novel periodontal regeneration using secreted factors from mesenchymal stem cells and clarification of its regenerative mechanisms.

2013 - 2017 Development of phototherapy using lasers and LEDs for the treatment and prevention of periodontitis and peri-implantitis

2015 - 2016 重症褥瘡モデルの作製と間葉系幹細胞を用いた新規治療法の検討

2012 - 2015 New therapy for Periventricular leucomalacia using mesenchymal stem cell

2012 - 2015 Nobel periodontal regenerative therapy using paracrine factors from stem cells

2012 - 2015 A novel periodontal tissue regeneration method using a printing technology

2012 - 2014 Elucidation of tissue regenerative mechanism caused by MSC derived-exosomes

2010 - 2012 Development of innovative treatment methods using light energy for periodontitis and peri-implantitis

2010 - 2011 Examination of pathogenesis of periodontal disease through ascorbic acid transporter SVCTs

2009 - 2011 New strategy based on the organogenesis signal control for periodontal disease

2008 - 2010 Cell-patterning technology for epithelial rest of Malassez network and its application for periodontal regeneration

2008 - 2009 Functional analysis of amelotin and its application for periodontal regeneration.

2007 - 2009 Application of the Er : YAG laser for periodontal therapy and clarification of the biological effects

2006 - 2007 新規エナメルタンパク・アメロティンの機能解析

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Papers (60)：

Yihao PENG, Kengo IWASAKI, Yoichiro TAGUCHI, Makoto UMEDA. MSC-extract inhibits LPS-induced TNFα expression in THP-1. Journal of Osaka Dental University. 2024. 58. 1. 1-5
Yufan Wu, Kengo Iwasaki, Yoshiya Hashimoto. Induction of mesenchymal stem cell (MSC) differentiation from iPS cells using MSC medium. Dental materials journal. 2024. 43. 1. 20-27
Tomoko Kanda, Kengo Iwasaki, Yoichiro Taguchi, Makoto Umeda. Ascorbic Acid Promotes Proliferation of Periodontal Ligament Fibroblasts. Journal of Hard Tissue Biology. 2024. 33. 3. 139-142
KANDA Ryuhei, IWASAKI Kengo, FUJINO Takehiko, KAWAZOE Takayoshi. Plasmalogen inhibits MMP-1 production by TNFα in human gingival fibroblasts. Journal of Osaka Dental University. 2023. 57. 2. 233-237
Yihao Peng, Kengo Iwasaki, Yoichiro Taguchi, Makoto Umeda. The extracts of mesenchymal stem cells induce the proliferation of periodontal ligament cells. Journal of Osaka Dental University. 2023. 57. 1. 119-124

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MISC (5)：

神田龍平, 岩崎剣吾, 彭一豪, 梅田誠, 藤野武彦, 川添堯彬. 血管内皮細胞におけるICAM-1発現量に対するプラズマローゲンの影響. 日本歯周病学会会誌. 2022. 64. 春季特別. 126-126
Kong Sophannary, Aoki Akira, Iwasaki Kengo, Mizutani Koji, Suda Tomonari, Katagiri Sayaka, Ogita Mayumi, Ando Yoshinori, Izumi Yuichi. ヒト歯肉線維芽細胞の増殖に及ぼすEr:YAGレーザー照射の効果(Effects of Er:YAG laser irradiation on proliferation of human gingival fibroblasts). 日本歯周病学会会誌. 2017. 59. 春季特別. 118-118
秋月達也, 小田茂, 佐藤郁文, 岩崎剣吾, 田中敬子, 岩田隆紀, 川勝紀子, 矢代麗子, 大和雅之, 岡野光夫, et al. 歯根膜シートを用いた歯周組織再生療法. 日本歯科医師会雑誌. 2008. 61. 5. 510-510
K Iwasaki, K Noguchi, Ishikawa, I. PGE(2) downregulates LPS-induced IL-12 production via EP4 in monocytes. JOURNAL OF DENTAL RESEARCH. 2001. 80. 4. 1335-1335
K Iwasaki, K Noguchi, Ishikawa, I. Prostaglandin E-2 and I-2 regulate intercellular adhesion molecule-1 expression in interleukin-1-beta-stimulated hunan gingival fibroblasts. (vol 34, pg 97, 1999). JOURNAL OF PERIODONTAL RESEARCH. 1999. 34. 4. 232-232

Education (2)：

1997 - 2001 東京医科歯科大学医歯学総合研究科歯周病学講座大学院
1991 - 1997 Tokyo Medical and Dental University Faculty of Dentistry School of Dentistry

Professional career (1)：

Work history (8)：

2021/10 - 現在 Division of Creative and Integrated Medicine, Advanced Medicine Research Center, Translational Research Institute of Medical Innovation (TRIMI), Osaka Dental Univeristy, TRIMI Advanced Research Center
2018/08 - 2021/09 Osaka Dental University Institute of Dental Research Lecturer
2014/04 - 2018/03 Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Department of Nanomedicine (DNP) Lecturer
2010/04 - 2014/03 Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Department of Nanomedicine (DNP) Assistant Professor
2009/04 - 2010/03 Tokyo Women’s Medical University, School of Medicine Department of Oral and Maxillofacial Surgery Assistant Professor

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Awards (5)：

2023/10 - Japanese Society of Periodontology JSP Outstanding Presentation Award for Periodontal Regenerative Medicine Novel periodontal regenerative strategy using protein extract from mesenchymal stem cells
2015/05 - Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology JOMSMP 2015 Oral and Maxillofacial Surgery Section Award Identification of periodontal bacteria from carotid artery plaque in chronic periodontitis patients.
2013 - 日本炎症・再生医学会第34回日本炎症・再生医学会優秀演題賞歯根膜幹細胞培養上清を用いたラット歯周組織の再生
2012 - 日本炎症・再生医学会第33回日本炎症・再生医学会優秀演題賞歯根膜幹細胞転写羊膜移植によるラット歯周組織の再生
2001 - International Association for Dental Research International Association for Dental Research (IADR)/ Unilever Division Travel Award PGE2 down-regulates LPS-induced IL-12 production via EP4 in monocytes

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