Rchr
J-GLOBAL ID：201801017417478343   Update date: Feb. 01, 2024

Uechi Tamayo

ウエチ タマヨ | Uechi Tamayo
Affiliation and department：
University of Miyazaki Faculty of Medicine School of Medicine

About University of Miyazaki Faculty of Medicine School of Medicine


Job title： Associate Professor
Research field  (2)： Hematology and oncology ,  Molecular biology
Research keywords  (4)： 翻訳異常 ,  ゼブラフィッシュ ,  先天性貧血 ,  リボソーム
Research theme for competitive and other funds  (16)：
  • 2022 - 2026 翻訳後修飾としてのチロシン硫酸化の空間および時間的制御機構の理解と機能解明
  • 2022 - 2025 先天性貧血を引き起こすmRNA特異的な翻訳調節機構の解明
  • 2020 - 2023 Development of a zebrafish model of ribosomopathy for disease pathogenesis and drug discovery
  • 2019 - 2022 先天性貧血の発症に関与するmRNA選択的な翻訳調節機構の解明
  • 2017 - 2019 Selected mRNA translation and ribosomopathies(Fostering Joint International Research)
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Papers (28)：
  • Hideaki Matsui, Junko Ito, Noriko Matsui, Tamayo Uechi, Osamu Onodera, Akiyoshi Kakita. Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease. Nature communications. 2021. 12. 1. 3101-3101
  • Basu A, Yoshihama M, Uechi T, Kenmochi N. Prokaryotic ribosomal RNA stimulates zebrafish embryonic innate immune system. BMC Research Notes. 2020. 13. 1
  • Palasin K, Uechi T, Yoshihama M, Srisowanna N, Choijookhuu N, Hishikawa Y, Kenmochi N, Chotigeat W. Abnormal development of zebrafish after knockout and knockdown of ribosomal protein L10a. Scientific Reports. 2019. 9. 1. 18130-18130
  • Uechi T, Kenmochi N. Zebrafish models of diamond-blackfan anemia: A tool for understanding the disease pathogenesis and drug discovery. Pharmaceuticals. 2019. 12. 4
  • McMahon M, Contreras A, Holm M, Uechi T, Forester CM, Pang X, Jackson C, Calvert ME, Chen B, Quigley DA, et al. A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS. eLife. 2019
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MISC (9)：
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Books (2)：
  • The role of alternative mRNA splicing in heart development
    Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension 2020 ISBN:9789811511844
  • 大・中・小動物実験プロトコル
    宮日文化情報センター 2016 ISBN:9784904186558
Lectures and oral presentations  (38)：
  • 先天性貧血とリボソームの異常 〜ゼブラフィッシュを用いて未知の翻訳機構の解明をめざす〜
    (第27回 八幡平造血セミナー)
  • 先天性貧血とリボソームの異常 〜ゼブラフィッシュを用いて道の翻訳機構の解明をめざす〜
    (第27回 八幡平造血セミナー)
  • ゼブラフィッシュを用いたリボソーム病発症機構の解析と創薬スクリーニング
    (第42回日本分子生物学会年会)
  • Loss of rRNA modifications alters the efficiency of tRNA accommodation
  • Translational efficiency of mRNAs required for hematopoiesis were decreased in a zebrafish model of Diamond-Blackfan anemia
    (COLD SPRING HARBOR LABORATORY MEETING ON ‘TRANSLATIONAL CONTROL)
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Professional career (1)：
  • 博士(医学) (琉球大学)
Work history (1)：
  • 2019/03/01 - 現在 University of Miyazaki Faculty of Madicine School of Madicine Associate Professor
Association Membership(s) (3)：
国際RNA学会 ,  日本分子生物学会 ,  日本RNA学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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