Hagiwara Koichi

ハギワラコウイチ | Hagiwara Koichi

Affiliation and department：
Homepage URL (1)： http://www.f.u-tokyo.ac.jp/~inoue/

Research field (1)： Pharmaceuticals - chemistry and drug development

Research theme for competitive and other funds (6)：

2021 - 2023 ステロイド型4環性骨格を有する高酸化度天然物の網羅的合成手法の開発
2017 - 2022 Application of hybrid catalysis-mediated multi-component coupling reactions for efficient construction of densely functionalized natural products
2017 - 2022 Expanding the medicinally relevant chemical space with architecturally complex natural products and their synthetic analogues
2019 - 2021 Comprehensive total synthesis of dihydro-beta-agarofurans toward the invention of new bioactive molecules
2017 - 2019 Comprehensive total synthesis of diterpenoid alkaloids toward the invention of new molecules acting on ion channels

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Papers (14)：

Hiroyuki Mutoh, Yuuki Watanabe, Daiki Kamakura, Koichi Hagiwara, Masayuki Inoue. Unexpected Formation of 11(9→7)-abeo-Steroid Skeleton in Synthetic Studies toward Batrachotoxin. Chemical and Pharmaceutical Bulletin. 2024. 72. 4. 360-364
Hibiki Asai, Koichi Hagiwara, Masayuki Inoue. Enantioselective route to an AE-ring intermediate in the total synthesis of talatisamine. Tetrahedron Letters. 2024. 135. 154903-154903
Yuuki Watanabe, Komei Sakata, Daisuke Urabe, Koichi Hagiwara, Masayuki Inoue. Formal Total Synthesis of Batrachotoxin Enabled by Radical and Weix Coupling Reactions. The Journal of Organic Chemistry. 2023. 88. 24. 17479-17484
Yuuki Watanabe, Hisahiro Morozumi, Hiroyuki Mutoh, Koichi Hagiwara, Masayuki Inoue. Total Synthesis of (-)-Batrachotoxin Enabled by a Pd/Ag-Promoted Suzuki-Miyaura Coupling Reaction. Angewandte Chemie International Edition. 2023. 62. 40. e202309688
Tsukasa Shimakawa, Shu Nakamura, Hibiki Asai, Koichi Hagiwara, Masayuki Inoue. Total Synthesis of Puberuline C. Journal of the American Chemical Society. 2023. 145. 1. 600-609

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MISC (10)：

Submitted by, N. Zhu, W.-M. Wan, H. Bao, Checked by Y, Watanabe, K. Hagiwara, M. Inoue. Reductive Deuteration of Ketones with Magnesium and D2O for the Synthesis of α-Deutero-o-methyl-benzhydrol. Organic Syntheses. 2021. 98. 51-67
Maciej Krzeszewski, Mariusz Tasior, Marek Grzybowski, Daniel T. Gryko, Checked by Shu Nakamura, Koichi Hagiwara, Masayuki Inoue. Synthesis of Tetraaryl-, Pentaaryl-, and Hexaaryl-1,4-dihydropyrrolo[3,2-b]pyrroles. Organic Syntheses. 2021. 98. 242-262
Submitted by, S. M. Engle, T. R. Kirkner, C. B. Kelly, Checked by, S. Shimizu, K. Hagiwara, M. Inoue. Preparation of 2,4,5,6-Tetra(9H-carbazol-9-yl)isophthalonitrile. Organic Syntheses. 2019. 96. 455-473
Submitted by, B, J. Simmons, M. Ramirez, N. K. Garg, Checked by, T. Shimakawa, K. Hagiwara, M. Inoue. Facile Reduction of Amides Using Nickel Catalysis: Reduction of 12-Aminododecanolactam. Organic Syntheses. 2019. 96. 436-454
島川典, 鎌倉大貴, 占部大介, 萩原浩一, 井上将行. タラチサミンAE環の効率的合成. 日本薬学会関東支部大会講演要旨集. 2017. 61st

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Professional career (1)：

Awards (1)：

Association Membership(s) (3)：

日本化学会 , THE PHARMACEUTICAL SOCIETY OF JAPAN , THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN

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