Research field (3)：
Nanobioscience
, Nanomaterials
, Molecular biochemistry
Research keywords (5)：
Nano/Bio Materials
, DNA Nanotechnology
, Applied Chemistry
, Biorelevant Chemistry
, Nucleic Acids Chemistry
Research theme for competitive and other funds (6)：
2021 - 2024 Retroviral integration into topologically-interlocked DNAs to probe the role of DNA structure and screen viral inhibitors
2021 - 2022 Development of stable DNA origami structures under application-specific conditions
2021 - 2022 Development of chemical methods to stabilize DNA nanomaterials for handling biomass-related enzymes
2020 - 2021 DNA origami-based chemiresistive sensors for chemical and biological detections
2016 - 2018 Development of new method for screening anticancer drugs that target topoisomerases by using DNA origami
2011 - 2013 Development of biomolecular nanosystem using DNA origami
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Papers (46)：
Kirankumar Krishnamurthy, Arivazhagan Rajendran, Eiji Nakata, Takashi Morii. Near Quantitative Ligation Results in Resistance of DNA Origami Against Nuclease and Cell Lysate. Small Methods. 2023
Arivazhagan Rajendran, Kirankumar Krishnamurthy, Seojeong Park, Eiji Nakata, Youngjoo Kwon, Takashi Morii. Topologically-Interlocked Minicircles as Probes of DNA Topology and DNA-Protein Interactions. Chemistry (Weinheim an der Bergstrasse, Germany). 2022. 28. 22. e202200108
Arivazhagan Rajendran, Kirankumar Krishnamurthy, Seojeong Park, Eiji Nakata, Youngjoo Kwon, Takashi Morii. Topologically-Interlocked Minicircles as Probes of DNA Topology and DNA-Protein Interactions. Chemistry (Weinheim an der Bergstrasse, Germany). 2022. 28. 22. e202200839
Zhengxiao Zhang, Eiji Nakata, Huyen Dinh, Masayuki Saimura, Arivazhagan Rajendran, Kazunari Matsuda, Takashi Morii. Tuning the Reactivity of a Substrate for SNAP-Tag Expands Its Application for Recognition-Driven DNA-Protein Conjugation. Chemistry (Weinheim an der Bergstrasse, Germany). 2021. 27. 72. 18118-18128
Arivazhagan Rajendran, Kirankumar Krishnamurthy, Amulya Giridasappa, Eiji Nakata, Takashi Morii. Stabilization and structural changes of 2D DNA origami by enzymatic ligation. Nucleic acids research. 2021. 49. 14. 7884-7900
Arivazhagan Rajendran, Narumi Shigi, Jun Sumaoka, Makoto Komiyama. Artificial Restriction DNA Cutter Using Nuclease S1 for Site-Selective Scission of Genomic DNA. Current Protocols in Nucleic Acid Chemistry. 2019. 76. 1
Arivazhagan Rajendran, Narumi Shigi, Jun Sumaoka, Makoto Komiyama. Affinity Isolation of Defined Genomic Fragments Cleaved by Nuclease S1-based Artificial Restriction DNA Cutter. Current Protocols in Nucleic Acid Chemistry. 2019. 76. 1
A. Rajendran, S. Park, 中田栄司, Y. Kwon, 森井孝. Topologically interlocked DNA nanostructures inside a DNA origami. The 97th CSJ Annual Meeting, Tokyo, 2017.3.16-20. 2017
Arivazhagan Rajendran, Yue Li, Masayuki Endo, Hiroshi Sugiyama. Direct observation of G-quadruplexes using DNA origami nanoscafiold. Biological Relevance and Therapeutic Applications of DNA and RNA Quadruplexes. 2015. 39-54
A. Rajendran, M. Endo, K. Hidaka, H. Sugiyama. Two-Dimensional Self-Assembly and Photo-Cross-Linking Induced Thermal-Stabilization of DNA Origami Structures. 9th Conference on the Foundations of Nanoscience 2012, Snowbird, UT. 2012
2005 - 2008 Graduate School of Science, Tohoku University, Japan Department of Chemistry Ph.D. Chemistry
2001 - 2003 School of Chemical Sciences, University of Madras, India Department of Inorganic Chemistry M.Sc. Inorganic Chemistry
1998 - 2001 Periyar University, India Department of Chemistry B.Sc. Chemistry
Work history (4)：
2015/02 - 現在 Institute of Advanced Energy, Kyoto University In Collaboration with Prof. Takashi Morii Junior Associate Professor
2013/09 - 2015/01 Life Science Center of TARA, University of Tsukuba Prof. Makoto Komiyama Lab Assistant Professor
2010/01 - 2013/08 WPI-iCeMS & Department of Chemistry, Kyoto University Prof. Hiroshi Sugiyama Lab CREST & JSPS Postdoctoral Researcher
2008/11 - 2009/12 FIBER, Konan University Prof. Naoki Sugimoto Lab Postdoctoral Researcher
Committee career (3)：
2017/01 - 現在 Japan Society of Nucleic Acids Chemistry (JSNAC) Member
2010/01 - 現在 The Chemical Society of Japan (CSJ) Member
2010/01 - 現在 The Biofunction-Related Chemistry Subcommittee Member
Awards (2)：
2011/11 - The 38th International symposium on nucleic acid chemistry Outstanding Poster Presentation Award Programmed self-assembly and thermal-stabilization of DNA origami nanostructures
2008/06 - Analytical Sciences Hot Article Award A pyrazine-based fluorescence-enhancing ligand with a high selectivity for thymine in AP site-containing DNA duplexes
