Rchr
J-GLOBAL ID：201801017644376360
Update date: Nov. 04, 2024
Sumikama Takashi
スミカマ タカシ | Sumikama Takashi
Affiliation and department：
Job title：
Assistant Professor
Homepage URL (1)：
https://www.researchgate.net/profile/Takashi_Sumikama
Research field (4)：
Biophysics
, Basic physical chemistry
, Bio-, chemical, and soft-matter physics
, Physiology
Research theme for competitive and other funds (15)：
- 2024 - 2028 Theoretical development of simultaneous measurements of molecular structure and dynamics using atomic force microscopy and its application to real molecules
- 2024 - 2027 Understanding ion selectivity of ion channels
- 2024 - 2026 Deciphering the design principles of the genome through the analysis of its potential instability
- 2024 - 2025 Deciphering A Novel Gate Operation Pathway of Lipopolysaccharide Transport by Bacterial ABC Transporters MsbA and LptC through A Multidimensional Approach
- 2020 - 2024 Elucidation of dynamics of chromosomes by simulation and comparison with experiments
- 2020 - 2021 Elucidation of molecular mechanism of interaction between phospholipase A2 and membrane by a combination of atomic force microscopy and molecular dynamics simulation
- 2019 - 2020 Toward simulating dynamics of chromatin at high resolution
- 2019 - 2020 Comparisons between theoretically computed and experimentally measured 3D-AFM topographic images of fibers
- 2017 - 2020 Elucidation of polymerization mechanism of ion channels and its physiological significance
- 2018 - 2019 Revealing the physical origin of AFM images on soft matters: a computational and experimental study
- 2016 - 2017 Unifying the permeation mechanisms through several K+ channels
- 2014 - 2017 Mechanism underlying the clustering-dispersion dynamics of the channel protein on the membrane
- 2014 - 2016 Development of a theory to describe ion permeation and selectivity through potassium channels
- 2012 - 2013 Theoretical study on ion selectivity through the K+ channel
- 2011 - 2012 Elucidation of microscopic mechanism of gating of the K+ channel
Show all
Papers (30)：
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Ayumi Sumino, Takashi Sumikama, Yimeng Zhao, Holger Flechsig, Kenichi Umeda, Noriyuki Kodera, Hiroki Konno, Motoyuki Hattori, Mikihiro Shibata. High-Speed Atomic Force Microscopy Reveals Fluctuations and Dimer Splitting of the N-Terminal Domain of GluA2 Ionotropic Glutamate Receptor-Auxiliary Subunit Complex. ACS Nano. 2024. 18. 25018-25035
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Mohammad Shahidul Alam, Marcos Penedo, Takashi Sumikama, Keisuke Miyazawa, Kaori Hirahara, Takeshi Fukuma. Revealing the Mechanism Underlying 3D-AFM Imaging of Suspended Structures by Experiments and Simulations. Small Methods. 2024. 2400287
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Damien Hall, Holger Flechsig, Takashi Sumikama. Computational biophysics of atomic force microscopy-an IUPAB-sponsored workshop. Biophysical Reviews. 2023. 15. 2041-2044
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Ayumi Sumino, Takashi Sumikama, Mikihiro Shibata, Katsumasa Irie. Voltage sensors of a Na+ channel dissociate from the pore domain and form inter-channel dimers in the resting state. Nature Communications. 2023. 14. 7835
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Takashi Sumikama. Computation of topographic and three-dimensional atomic force microscopy images of biopolymers by calculating forces. Biophysical Reviews. 2023. 15. 2059-2064
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MISC (30)：
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Ayumi Sumino, Takashi Sumikama, Yimeng Zhao, Holger Flechsig, Kenichi Umeda, Noriyuki Kodera, Motoyuki Hattori, Mikihiro Shibata. High-speed AFM reveals fluctuations and dimer splitting of the N-terminal domain of GluA2-γ2. 2023
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Ayumi Sumino, Takashi Sumikama, Mikihiro Shibata, Katsumasa Irie. Interchannel dimerization of the dissociated voltage-sensor domains of voltage-gated Na+ channels in the resting state. Research Square. 2023
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Ayumi Sumino, Takashi Sumikama, Leonardo Puppulin, Mikihiro Shibata, Katsumasa Irie. Dissociation and inter-channel dimerization of voltage-sensor domains (VSD) of voltage-gated Na+ channel in the resting state. Journal of Physiological Sciences. 2023. 73. 95
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Katsumasa Irie, Yoshinori Oda, Takashi Sumikama, Atsunori Oshima, Yoshinori Fujiyoshi. The structural basis of the divalent cation blocking on tetrameric cation channel. Research Square. 2023
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Shotaro Tsujioka, Ayumi Sumino, Yutaro Nagasawa, Takashi Sumikama, Holger Flechsig, Leonardo Puppulin, Takuya Tomita, Yudai Baba, Takahiro Kakuta, Tomoki Ogoshi, et al. Evolutionarily acquired activity-dependent transformation of the CaMKII holoenzyme. bioRxiv. 2023
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Patents (1)：
Lectures and oral presentations (152)：
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原子間力顕微鏡を用いた細胞内オルガネラの3次元構造の可視化技術とその理論基盤
(極限環境生物学会シンポジウム 2024)
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Phosphorylation-dependent clustering mechanism of CaMKII revealed by high-speed AFM
(Science for Neuroscience 2024)
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Single-molecule nanodynamics of AMPA-type glutamate receptors by high-speed atomic force microscopy
(Science for Neuroscience 2024)
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Computational simulations supporting observations by atomic force microscopy
(The Second International Symposium of Nano Life Science: Nano Biotechnology, Biophysics and Computation (NanoBioCoM2024) 2024)
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Insights into chromatin organization obtained by a rapid classification of A/B compartments from Hi-C data
(21st IUPAB & 62nd BSJ Joint Congress 2024 2024)
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Education (1)：
- 2005 - 2008 Nagoya University Department of Chemistry, Graduate School of Science
Professional career (1)：
- Ph.D. (Nagoya University)
Work history (6)：
Committee career (3)：
- 2024/01 - 2024/12 日本生物物理学会 分野別専門委員(イオン透過)
- 2018/01 - 2018/12 日本生物物理学会 分野別専門委員(イオン透過)
- 2016/01 - 2016/12 日本生物物理学会 分野別専門委員(イオン透過)
Awards (5)：
- 2019/09 - Kanazawa University Papers of the Month
- 2018/03 - The Physiological Society of Japan Irisawa Memorial Promotion Award for Young Physiologists
- 2017/07 - University of Fukui Best paper award
- 2017/03 - The Biophysical Society of Japan, local meeting in Chubu Best presentation award
- 2016/11 - University of Fukui Excellent paper award
Association Membership(s) (4)：
The Molecular Biology Society of Japan
, The Physiological Society of Japan
, The Biophysical Society
, The Biophysical Society of Japan
