Yasuhiro Yoshida

Research field (1)： Zoological sciences

Research theme for competitive and other funds (23)：

2022 - 2025 Analysis of lung inflammation mechanisms associated with cytokine storms
2021 - 2024 Elucidation of the mechanism of steroid-structure anticancer drug resistance to leukemia cells and application to personalized diagnosis
2021 - 2024 加熱式タバコなど新規タバコ関連商品の有害性を動物実験より評価し健康被害を予防する
2020 - 2023 Establishment of clot biopsy aiming at development of a simple method for early detection of COPD
2020 - 2023 大気中粒子による眼アレルギー疾患の疫学調査と実験的手法による原因究明と治療法開発

2017 - 2019 Analysis of particulate matter induced-inflammation that was focused on neutrophil endocytosis

2013 - 2016 Epidemiological and experimental studies for evaluation of biological effects by Asian smoke (hazy events) derived from Chinese continent.

2012 - 2015 An evaluation of environmental pollutant exposure using cell survival signaling and development of simple detection system

2011 - 2013 The influence on bone marrow cells of the indoor environment chemicals: Analysis of dendritic cell differentiation and the Treg induction

2011 - 2013 Developmental neurotoxicity of volatile organic compounds: the evaluation of social behaviors and the developing of biomarkers

2011 - 2013 An analysis of the mechanisms of loss of immune system in T cell induced by p53 gene instability after irradiation at a young age

2010 - 2012 Effects of Asian sand dust on airway diseases and genetic susceptibility factors for exacerbation of allergic diseases

2009 - 2011 BDNF produced by leukemia cells induced regulatory T cells

2009 - 2010 黄砂感染症の健康影響評価を目指した実験的パイロットスタディ

2008 - 2010 Analysis of biomarker for septic shock

2007 - 2009 Evaluation of effects of aldehyde dehydrogenase on oxidative stress

2007 - 2008 The effect of inhalation of an indoor environmental chemical during pregnancy and infancy on mast cell

2007 - 2008 Effect of BDNF on proliferation of leukemic cells and application to the treatment.

2006 - 2008 Evaluation of neurotoxic effects induced by gaseous chemical substances on the CNS of the next generation

2005 - 2006 TRAF6変異体導入による白血病細胞の増殖制御解析と新たな治療法への応用

2005 - 2006 Growth inhibition of adult T-cell leukemia cells through the Toll-like receptor signaling

2004 - 2005 Studies on the pleiotropic effects of gaseous chemical compound on the function of the central nervous system.

2003 - 2004 Mechanism of enhanced production of prostaglandins in BALB/c macrophages

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Papers (65)：

Riho Kurata, Masamitsu Harada, Jun Nagai, Xiaofeng Cui, Takayuki Isagawa, Hiroaki Semba, Yasuhiro Yoshida, Norihiko Takeda, Koji Maemura, Tomo Yonezawa. Nucleoside Triphosphate Hydrolases Assay in Toxoplasm gondii and Neospora caninum for High-Throughput Screening using a Robot Arm. Journal of visualized experiments : JoVE. 2022. 185
Yuan Song, Ryuji Okazaki, Yasuhiro Yoshida. Senescence-associated secretory phenotype and activation of NF-κB in splenocytes of old mice exposed to irradiation at a young age. Developmental & Comparative Immunology. 2021. 122. 104124-104124
Masamitsu Harada, Jun Nagai, Riho Kurata, Xiaofeng Cui, Takayuki Isagawa, Hiroaki Semba, Yasuhiro Yoshida, Norihiko Takeda, Koji Maemura, Tomo Yonezawa. Establishment of Novel Protein Interaction Assays between Sin3 and REST Using Surface Plasmon Resonance and Time-Resolved Fluorescence Energy Transfer. International journal of molecular sciences. 2021. 22. 5
Duo Wang, Mengyue Shen, Noriaki Kitamura, Yusuke Sennari, Kentaro Morita, Junichi Tsukada, Tamotsu Kanazawa, Yasuhiro Yoshida. Mitogen-activated protein kinases are involved in cucurbitacin D-induced antitumor effects on adult T-cell leukemia cells. Investigational new drugs. 2021. 39. 1. 122-130
Mengyue Shen, Yuan Song, Takamichi Ichinose, Kentaro Morita, Duo Wang, Keiichi Arashidani, Yasuhiro Yoshida. In vivo immune activation of splenocytes following exposure to tar from Asian sand dust. Journal of toxicology and environmental health. Part A. 2020. 83. 19-20. 649-658

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MISC (67)：

Tomo Yonezawa, Riho Kurata, Cui Xiaofeng, Harada Masamitsu, Nagai Jun, Yoshida Ysuhiro. Novel Reporter System Monitoring IL-18 Specific Signaling can be Applied to High-Throughput Screening. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2020. 93. 0. 1-LBS-10
米澤朋, 倉田里穂, 熊谷飛鳥, 熊谷飛鳥, 尾崎惠一, 吉田安宏. 大気汚染物質を評価するための分泌型アルカリフォスファターゼを用いたリポーター細胞の樹立. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
市瀬孝道, 吉田成一, 定金香里, 吉田安宏, 嵐谷奎一, 伊藤智彦, 鳥羽陽, MIAO He. 黄砂とPM_2.5の呼吸器への影響-肺の炎症誘導とアレルギー増悪作用-. 大気環境学会年会講演要旨集. 2018. 59th
倉田里穂, 熊谷飛鳥, CUI Xiaofeng, 原田将光, 永井潤, 吉田安宏, 尾崎惠一, 米澤朋. ヒト分泌型アルカリホスファターゼ発現を安定に維持する新規レポーター細胞の樹立. 日本分子生物学会年会プログラム・要旨集(Web). 2018. 41st. ROMBUNNO.1LBA-132 (WEB ONLY)
熊谷飛鳥, 清水謙次, 倉田里穂, 崔蕭鋒, 砂河孝行, 原田将光, 永井潤, 吉田安宏, 尾崎惠一, 米澤朋. 多様なヒトIL18組換えタンパク質を安定に分泌する新規細胞の樹立. 日本分子生物学会年会プログラム・要旨集(Web). 2018. 41st. ROMBUNNO.2LBA-149 (WEB ONLY)

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