Rchr
J-GLOBAL ID:201801017725376241
Update date: Sep. 26, 2024
Imamura Toshihiko
イマムラ トシヒコ | Imamura Toshihiko
Affiliation and department:
Research field (1):
Fetal medicine/Pediatrics
Research keywords (4):
分子生物学
, 小児血液
, 急性リンパ性白血病
, 小児造血器腫瘍
Research theme for competitive and other funds (7):
- 2022 - 2025 The development of CAR-T therapy targeting FLT3 and CD19 for infant acute lymphoblastic leukemia
- 2021 - 2024 Investigation of leukemogenic mechanism of intractable pediatric leukemia
- 2019 - 2022 Development of CAR-T cell therapy for KMT2A-rearranged acute lymphoblastic leukemia
- 2017 - 2020 Mechanistic analysis of drug-resistance in ALL
- 2011 - 2013 Identification of new therapeutic target for MLL rearranged acute myeloid leukemia
- 2009 - 2010 Analysis of leukemogenic mechanism of MLL-AF4 family and development of new therapeutic strategy of MLL-rearranged acute leukemia
- 2007 - 2008 Analysis of leukemogenic mechanism of MLL-AF4 family fusion protein
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Papers (239):
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Anna Østergaard, Marta Fiocco, Hester de Groot-Kruseman, Anthony V Moorman, Ajay Vora, Martin Zimmermann, Martin Schrappe, Andrea Biondi, Gabriele Escherich, Jan Stary, et al. ETV6::RUNX1 Acute Lymphoblastic Leukemia: how much therapy is needed for cure?. Leukemia. 2024. 38. 7. 1477-1487
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Shunsuke Kimura, Chun Shik Park, Lindsey E Montefiori, Ilaria Iacobucci, Petri Polonen, Qingsong Gao, Elizabeth D Arnold, Andishe Attarbaschi, Anthony Brown, Barbara Buldini, et al. Biologic and clinical analysis of childhood gamma delta T-ALL identifies LMO2/STAG2 rearrangements as extremely high-risk. Cancer discovery. 2024
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Hisashi Ishida, Toshihiko Imamura, Ryoji Kobayashi, Yoshiko Hashii, Takao Deguchi, Takako Miyamura, Megumi Oda, Masaki Yamamoto, Keiko Okada, Hideki Sano, et al. Differential impact of asparaginase discontinuation on outcomes of children with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma. Cancer Medicine. 2024. 13. 12
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Hirohito Kubota, Hiroo Ueno, Keiji Tasaka, Tomoya Isobe, Satoshi Saida, Itaru Kato, Katsutsugu Umeda, Mitsuteru Hiwatari, Daiichiro Hasegawa, Toshihiko Imamura, et al. RNA-seq-based miRNA signature as an independent predictor of relapse in pediatric B-cell acute lymphoblastic leukemia. Blood Advances. 2023
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Akira Nishimura, Kazuaki Yokoyama, Takuya Naruto, Chika Yamagishi, Toshihiko Imamura, Hiroto Nakazono, Shunsuke Kimura, Mieko Ito, Maiko Sagisaka, Yukie Tanaka, et al. Myeloid/natural killer (NK) cell precursor acute leukemia as a distinct leukemia type. Science advances. 2023. 9. 50. eadj4407
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MISC (217):
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戒能明, 坂本謙一, 坂本謙一, 森谷邦彦, 今村俊彦, 工藤寿子, 塩田曜子, 今宿晋作, 森本哲. Sensorineural hearing loss caused by Langerhans cell histiocytosis: the possible risk of the CNS related consequence. 日本小児科学会雑誌. 2024. 128. 2
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森本 哲, 塩田 曜子, 坂本 謙一, 工藤 耕, 今村 俊彦, 工藤 寿子. ランゲルハンス細胞組織球症における病態解明と治療の展望-Elucidated pathogenesis and therapeutic prospects in Langerhans cell histiocytosis-第83回日本血液学会学術集会 ; Symposium 2 : Molecular Mechanism of Inflammation and Tumor in Histiocytic Disorders. 臨床血液. 2022. 63. 5. 373-382
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森谷 邦彦, 今村 俊彦, 片山 紗乙莉, 戒能 明, 岡本 賢治, 横山 能文, 植村 優, 北澤 宏展, 関水 匡大, 平松 英文, et al. BFM基盤のプロトコールで治療をした日本人小児急性リンパ性白血病における症候性骨壊死の発症率は欧米人と同時である(Incidence of symptomatic ON in pediatric ALL treated with BFM based protocol is similar to children in western countries). 日本小児科学会雑誌. 2022. 126. 2. 294-294
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森本 哲, 塩田 曜子, 坂本 謙一, 工藤 耕, 今村 俊彦, 工藤 寿子. 組織球性症候群における炎症と腫瘍の分子病態 解明されてきたLCHの病態と治療の展望(Elucidated pathogenesis and therapeutic prospects in LCH). 日本血液学会学術集会. 2021. 83回. SY2-3
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西村 聡, 横山 和明, 成戸 卓也, 中園 博仁, 木村 俊介, 今村 俊彦, 森尾 友宏, 金井 昭教, 松井 啓隆, 梅田 雄嗣, et al. 新規の白血病特性を有するmyeloid/natural killer cell precursor acute leukemia(Myeloid/natural killer(NK) cell precursor acute leukemia as a novel distinctive leukemia entity). 日本血液学会学術集会. 2021. 83回. PL-4
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Education (2):
- 1998 - 2002 Kyoto Prefectural University of Medicine Graduate School of Medical Science
- 1988 - 1994 Kyoto Prefectural University of Medicine
Professional career (1):
Work history (9):
- 2022/10 - 現在 京都府立医科大学大学院医学研究科 小児科学 准教授
- 2013/04 - 2022/09 Kyoto Prefectural University of Medicine
- 2008/07 - 2013/03 Kyoto Prefectural University of Medicine
- 2006/09 - 2008/06 Kyoto Prefectural University of Medicine
- 2004/09 - 2006/08 シカゴ大学 内科 血液腫瘍部門 博士研究員
- 2003/04 - 2004/08 松下記念病院 小児科
- 2002/04 - 2003/03 市立明石市民病院 小児科
- 1995/04 - 1998/03 国立舞鶴病院(現 舞鶴医療センター) 小児科
- 1994/05 - 1995/03 Kyoto Prefectural University of Medicine
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