Rchr
J-GLOBAL ID:201801018009995468   Update date: Oct. 19, 2024

Aiba Yuichiro

アイバ ユウイチロウ | Aiba Yuichiro
Affiliation and department:
Job title: Associate professor
Research field  (7): Molecular biology ,  Chemical biology ,  Molecular biochemistry ,  Biochemistry ,  Bioorganic chemistry ,  Functional biochemistry ,  Applied biochemistry
Research keywords  (8): Nucleic Acid Chemistry, Peptide Nucleic Acid, PNA, Peptide, Protein, Chemical Biology, Genetic Engineering, Protein Engineering, Molecular Biology, Bioorganic Chemistry, Bioinorganic Chemistry ,  Biofunctional Chemistry ,  Bioinorganic Chemistry ,  Bioorganic Chemistry ,  Molecular Biology ,  Chemical Biology ,  Peptide Nucleic Acid ,  Nucleic Acid Chemistry
Research theme for competitive and other funds  (30):
  • 2022 - 2025 ペプチド核酸(PNA)による細胞内核酸操作技術の開発(独立基盤形成支援 追加交付)
  • 2022 - 2025 ペプチド核酸(PNA)による細胞内核酸操作技術の開発
  • 2022 - 2023 ペプチド核酸(PNA)を用いた遺伝子工学技術の開発
  • 2022 - 2023 研究寄付金
  • 2021 - 2023 非翻訳RNA検出技術による創薬プラットフォーム創成事業
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Papers (51):
  • Yuya Yokoyama, Shinya Ariyasu, Masayuki Karasawa, Chie Kasai, Yuichiro Aiba, Hiroshi Sugimoto, Osami Shoji. Bacterial acyl homoserine lactones triggered non-native substrate hydroxylation catalysed by directed-evolution-derived cytochrome P450BM3 mutants. ChemCatChem. 2024
  • Honoka Kawamukai, Motonori Matsusaki, Takanari Tanimoto, Mai Watabe, Ken Morishima, Shunsuke Tomita, Yoichi Shinkai, Tatsuya Niwa, Taro Mannen, Hiroyuki Kumeta, et al. Conserved loop of a phase modifier endows protein condensates with fluidity. bioRxiv. 2024
  • Shoji, O, Ariyasu, S, Aiba, Y. Catalytic Oxidation of Methane by Wild-Type Cytochrome P450BM3 Exploiting Chemically Evolved Decoy Molecules. JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN. 2024. 82. 5. 505-512
  • Hiroaki Inaba, Yuma Shisaka, Shinya Ariyasu, Erika Sakakibara, Garyo Ueda, Yuichiro Aiba, Nobutaka Shimizu, Hiroshi Sugimoto, Osami Shoji. Heme-substituted protein assembly bridged by synthetic porphyrin: achieving controlled configuration while maintaining rotational freedom. RSC Advances. 2024. 14. 13. 8829-8836
  • Kodama, Y, Ariyasu, S, Karasawa, M, Aiba, Y, Shoji, O. Highly selective hydroxylation of gaseous alkanes at the terminal position by wild-type CYP153A33. 2023. 13. 21. 6146-6152
more...
Patents (1):
  • インベージョン複合体の形成方法
Books (7):
  • Heme-containing proteins: Structures, functions, and engineering.
    Oxford: Elsevier 2023 ISBN:9780128231531
  • デコイ分子によるシトクロムP450BM3の反応制御と水中での高難度水酸化反応
    シーエムシー出版 2022 ISBN:9784781316635
  • 酵素機能を化学的にハックする新規手法の開発
    触媒年鑑:触媒技術の動向と展望 2021年版・一般社団法人触媒学会 2021
  • ペプチド核酸と相分離
    相分離生物学の全貌, 現代化学 増刊46・東京化学同人 2020
  • シトクロムP450BM3の誤作動状態を利用したガス状アルカンの直接水酸化
    日本エネルギー学会機関誌 えねるみくす 2020
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Lectures and oral presentations  (53):
  • ペプチド核酸PNAを用いたペプチドおよび核酸研究
    (第13回化学フロンティア研究会 2024)
  • Sequence-specific recognition of double-stranded DNA using parallel-stranded peptide nucleic acids
    (20th Annual Meeting of the Oligonucleotide Therapeutics Society 2024)
  • 配列設計を利用したペプチド核酸(PNA)による2本鎖DNA認識
    (第73回高分子討論会 2024)
  • Parallel-stranded peptide nucleic acids for specific recognition of double-stranded DNA and their structural analysis
    (XXV International Round Table on Nucleosides, Nucleotides and Nucleic Acids 2024)
  • ペプチド核酸(PNA)を用いたDNAとペプチドの認識・制御
    (第56回 若手ペプチド夏の勉強会 2024)
more...
Education (3):
  • 2007 - 2010 The University of Tokyo School of Engineering Department of Chemistry and Biotechnology
  • 2005 - 2007 The University of Tokyo School of Engineering Department of Chemistry and Biotechnology
  • 2001 - 2005 The University of Tokyo Faculty of Engineering Department of Chemistry and Biotechnology
Work history (9):
  • 2021/04 - 現在 Graduate School of Science Division of Material Science Inorganic and Analytical Chemistry Associate Professor
  • 2015/11 - 現在 国立研究開発法人理化学研究所 研究員
  • 2020/07 - 2021/03 Nagoya University Graduate School of Science Division of Material Science Inorganic and Analytical Chemistry Associate Professor / Lecturer
  • 2015/07 - 2020/06 Nagoya University Graduate School of Science Division of Material Science Inorganic and Analytical Chemistry Assistant Professor
  • 2012/09 - 2015/06 University of Texas, Southwestern Medical Center Department of Pharmacology Researcher
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Committee career (20):
  • 2023/04 - 現在 日本化学会東海支部 幹事
  • 2024/10 - 2024/10 第61回ペプチド討論会 世話人
  • 2024/09 - 2024/09 錯体化学会第74回討論会 討論会実行委員
  • 2024/04 - 2024/04 The 3rd International Symposium on Biofunctional Chemistry (ISBC2024) Local executive committee
  • 2023/11 - 2023/11 第56回酸化反応討論会実行委員会 実行委員
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Awards (2):
  • 2012/06 - Research Group on Polymers and Biosciences, The Society of Polymer Science, Japan Presentation Award for Young Scientists of Symposium on Polymers and Biosciences
  • 2012/02 - Inoue Foundation for Science Inoue Research Award for Young Scientists
Association Membership(s) (10):
The Japanese Peptide Society ,  Oligonucleotide Therapeutics Society ,  日本ケミカルバイオロジー学会 ,  Society of Biological Inorganic Chemistry ,  化学フロンティア研究会 ,  The Japan Society of Nucleic Acids Chemistry ,  Forum on Biopolymers Science, SPSJ ,  Division of Biofunctional Chemistry, The Chemical Society of Japan ,  The Society of Polymer Science, Japan ,  The Chemical Society of Japan
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