Research theme for competitive and other funds (18):
2021 - 2024 Elucidation of the mechanism of persistent infection of Helicobacter pylori by oscillation-expressed sRNA
2019 - 2021 Approaching the darkness of oral Helicobacter pylori: exploratory research on isolation / identification, infection mechanism, and persistent infection regulators
2018 - 2021 Examination of the persistent infection mechanism of Helicobacter pylori by phage lysogenization
2017 - 2018 細菌外膜小胞への選択的物質導入機構の解明
2015 - 2017 Protective function of stomach-ILC2s induction of IgA for bacteria elimination
2013 - 2016 Host-microbe interaction mediated by intestinal M cells
2013 - 2016 ヘリコバクターピロリの病原性因子とワクチンに関する研究
2015 - 2016 ヘリコバクターピロリ新規エフェクターRNAの探索
2013 - 2015 Regulation and reconstruction of acquired memories in human microbiota
2014 - 2015 ピロリ菌関連胃がんの早期診断を目的とした腫瘍マーカーの探索
2014 - 2015 ヘリコバクターピロリ胃粘膜持続炎症の分子基盤と新規ワクチンへの応用
2013 - 2014 細菌由来新規ターゲティング型アジュバント分子モジュールの開発
2012 - 2013 持続感染病原細菌がコントロールする共生成立の分子機構
2011 - 2013 ヘリコバクターピロリ胃粘膜長期感染に必要な宿主・菌体因子の時空間的動態解析
2011 - 2012 宿主応答撹乱を誘導するヘリコバクターピロリ由来ncRNAの同定
2008 - 2010 ヘリコバクターピロリの胃粘膜感染機構と炎症惹起メカニズムの研究
2006 - 2007 ヘリコバクターピロリの胃粘膜感染成立における分子基盤の確立
2005 - 2006 ヘリコバクターピロリの胃粘膜感染機構の解明
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Papers (95):
Ryoko Nagata, Hiroki Sato, Shoji Takenaka, Junji Yokoyama, Shuji Terai, Hitomi Mimuro, Yuichiro Noiri. Analysis of Genetic Relatedness between Gastric and Oral Helicobacter pylori in Patients with Early Gastric Cancer Using Multilocus Sequence Typing. International Journal of Molecular Sciences. 2023. 24. 3. 2211-2211
Hidehiko Kikuchi, Kaori Harata, Sumiko Akiyoshi, Takefumi Sagara, Harishkumar Madhyastha, Hitomi Mimuro, Futoshi Kuribayashi. Coffee diterpenes, cafestol and kahweol, display cytotoxicity and all-<i>trans</i> retinoic acid-induced superoxide generating activity-enhancing ability in U937 cells. Fundamental Toxicological Sciences. 2023. 10. 6. 233-240
Hidehiko Kikuchi, Kaori Harata, Sumiko Akiyoshi, Takefumi Sagara, Harishkumar Madhyastha, Hitomi Mimuro, Futoshi Kuribayashi. Bifunctional activity of tangeretin (5,6,7,8,4'-pentamethoxyflavone) in suppression of cell growth and gene expression of the superoxide-generating system-related proteins in U937 cells. Fundamental Toxicological Sciences. 2022. 9. 5. 151-157
Ryo Kinoshita-Daitoku, Kotaro Kiga, Masatoshi Miyakoshi, Ryota Otsubo, Yoshitoshi Ogura, Takahito Sanada, Zhu Bo, Tuan Vo Phuoc, Tokuju Okano, Tamako Iida, et al. A bacterial small RNA regulates the adaptation of Helicobacter pylori to the host environment. Nature Communications. 2021. 12. 1
Phawinee Subsomwong, 大坪 亮太, 三室 仁美. 抗血清およびモノクローナル抗体によるマウス胃内ピロリ菌定着阻害効果(The anti-Helicobacter pylori colonization effect of serum and monoclonal antibody in the mice stomach). 日本細菌学雑誌. 2021. 76. 1. 90-90