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J-GLOBAL ID：201801018045521529   Update date: Feb. 01, 2024

Tanimura Ayako

タニムラ アヤコ | Tanimura Ayako
Affiliation and department：
The University of Shimane

About The University of Shimane


Job title： Associate professor
Research field  (6)： Immunology ,  Home economics, lifestyle science ,  Medical biochemistry ,  Pathobiochemistry ,  Molecular biology ,  Nutrition and health science
Research keywords  (8)： ER stress/UPR ,  Oxidative stress (ROS) ,  Energy metabolism ,  Reticular dysgenesis ,  Mitochondrial diseases ,  immune cells ,  Cellular differentiation ,  Mitochondria
Research theme for competitive and other funds  (8)：
  • 2021 - 2024 生体内リン代謝と老化を繋ぐ分子機序解明の研究基盤
  • 2021 - 2024 Clarification of the effect of butyric acid on macrophage differentiation and the development of new diet therapy for Crohn's disease
  • 2017 - 2020 Therapeutic development of immune deficiency with mitochondrial dysfunction using CoQ10
  • 2015 - 2018 Study on elucidation of the pathophysiology of rare intractable diseases (reticular dysgenesis) with severe combined immunodeficiency and development of therapeutic methods
  • 2013 - 2016 Clarification of the molecular mechanism and development of novel nutritional therapy of reticular dysgenesis as mitochondrial disease
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Papers (21)：
  • Jingxin Wang, Norikazu Saiki, Ayako Tanimura, Takafumi Noma, Akira Niwa, Tastutoshi Nakahata, Megumu K Saito. UK-5099, a mitochondrial pyruvate carrier inhibitor, recovers impaired neutrophil maturation caused by AK2 deficiency in human pluripotent stem cell models. Biochemical and biophysical research communications. 2023. 687. 149211-149211
  • Taigo Horiguchi, Ayako Tanimura, Keiko Miyoshi, Hiroko Hagita, Hisanori Minami, Takafumi Noma. The Effect of Heterozygous Mutation of Adenylate Kinase 2 Gene on Neutrophil Differentiation. International Journal of Molecular Sciences. 2022. 23. 24. 16089-16089
  • Keiko Miyoshi, Hiroko Hagita, Taigo Horiguchi, Ayako Tanimura, Takafumi Noma. Redefining GBA gene structure unveils the ability of Cap-independent, IRES-dependent gene regulation. Communications Biology. 2022. 5. 1
  • 谷村 綾子, 秋吉 澄子, 南 久則. 高菜漬けの地域別摂取状況と健康状態におよぼす影響-Intake of Takana-zuke, Salted Pickle of Takana (Brassica juncea var. integrifolia) and its relation to health status in Japan. 食生活研究. 2021. 41. 6. 366-380
  • Taigo Horiguchi, Yumiko Miyatake, Keiko Miyoshi, Ayako Tanimura, Hiroko Hagita, Hiroshi Sakaue, Takafumi Noma. Gene-expression profile reveals the genetic and acquired phenotypes of hyperactive mutant SPORTS rat. The journal of medical investigation : JMI. 2020. 67. 1.2. 51-61
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MISC (11)：
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Books (1)：
  • 管理栄養士養成のための栄養学教育モデル・コア・カリキュラム準拠 第2巻 栄養学の基本
    医歯薬出版 2022 ISBN:9784263720295
Lectures and oral presentations  (28)：
  • ミトコンドリアでのエネルギー代謝異常がもたらす好中球分化障害に対するエネルギー産生経路の変更による改善の検討
    (日本栄養食糧学会 九州・沖縄支部会 2020)
  • Can Fructose rescue the impairment of neutrophil differentiation due to failure of mitochondrial energy production?
    (2020)
  • アデニル酸キナーゼ2欠損血球系細胞の分化に対するフルクトースの効果
    (第23回日本病態栄養学会年次学術集会 2020)
  • クローン病モデルラットにおける血漿アミノ酸濃度の変化
    (第23回日本病態栄養学会年次学術集会 2020)
  • 腸内細菌叢に及ぼす食事脂質量と摂取時間の影響
    (第23回日本病態栄養学会年次学術集会 2020)
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Education (3)：
  • 2008 - 2011 The University of Tokushima Graduate School Institute of Health Biosciences Doctor's Course, Department of Clinical Nutrition, Master's Course, Department of Clinical Nutrition, Graduate School of Nutrition and Bioscience
  • 2006 - 2008 The University of Tokushima Graduate School Institute of Health Biosciences Master's Course, Department of Clinical Nutrition, Graduate School of Nutrition and Bioscience
  • 2002 - 2006 Tokushima University Faculty of Medicine School of Nutrition
Professional career (1)：
  • Ph.D. (Tokushima University)
Work history (3)：
  • 2023/04 - 現在 The University of Shimane Faculty of Nursing and Nutrition Department of Health and Nutrition
  • 2018/04 - 2023/03 Prefectural University of Kumamoto Faculty of Environmental and Symbiotic Sciences
  • 2011/04 - 2018/03 The University of Tokushima
Awards (1)：
  • 2008/06 - Japan Transporter Research Association Outstanding student award
Association Membership(s) (9)：
THE RESERCH SOCIETY for SCIENCE of DIETARY HABITS ,  THE JAPANESE SOCIETY OF NUTRITION AND DIETETICS ,  The Japan Dietetic Association ,  The Japanese Society of Mitochondrial Research and Medicine ,  The Japanese Society for Genome Editing ,  Japan Society of Nutrition and Food Science ,  Japan Society of Metabolism and Clinical Nutrition ,  The Japanese Biochemical Society ,  The Japan Association for the Integrated Study of Dietary Habits
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