Sugiyama Yuki

Research field (2)： Developmental biology , Cell biology

Research keywords (5)： basement membrane , tissue morphogenesis , planar cell polarity , cell polarity , lens

Research theme for competitive and other funds (1)：

2021 - 2022 Mechanobiological analysis of cell-basement membrane interaction during eye lens morphogenesis

Papers (22)：

J. W. McAvoy, L. J. Dawes, Y. Sugiyama, F. J. Lovicu. Intrinsic and extrinsic regulatory mechanisms are required to form and maintain a lens of the correct size and shape. EXPERIMENTAL EYE RESEARCH. 2017. 156. 34-40
Yuki Sugiyama, Elizabeth J. Shelley, Bradley K. Yoder, Zbynek Kozmik, Helen L. May-Simera, Philip L. Beales, Frank J. Lovicu, John W. McAvoy. Non-essential role for cilia in coordinating precise alignment of lens fibres. MECHANISMS OF DEVELOPMENT. 2016. 139. 10-17
Yuki Sugiyama, Elizabeth J. Shelley, Caroline Badouel, Helen McNeill, John W. McAvoy. Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2015. 56. 6. 4099-4107
Sook Hyun Chung, Mark Gillies, Yuki Sugiyama, Ling Zhu, So-Ra Lee, Weiyong Shen. Profiling of MicroRNAs Involved in Retinal Degeneration Caused by Selective Muller Cell Ablation. PLOS ONE. 2015. 10. 3
L. J. Dawes, Y. Sugiyama, F. J. Lovicu, C. G. Harris, E. J. Shelley, J. W. McAvoy. Interactions between lens epithelial and fiber cells reveal an intrinsic self-assembly mechanism. DEVELOPMENTAL BIOLOGY. 2014. 385. 2. 291-303

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MISC (4)：

杉山由樹. 水晶体上皮細胞の形態維持と増殖制御に非典型的カドヘリン蛋白 Fat1 が関与している. 日本白内障学会誌. 2017. 29. 84
杉山由樹. 眼の水晶体 (レンズ) をつくる - 老眼や白内障を克服できるか?. 理大科学フォーラム. 2015. 9. 9. 24-28
SUGIYAMA Y., SUZUKI A., KISHIKAWA M., AKUTSU R., HIROSE T., KATO K., WAYE Mary, OHNO S. A muscle-specific stress-responsible system which is composed of diversed members of the small heat shock protein family. 1998. 21. 211-211
DEYAMA Tetsuya, YAMASHITA Akio, HIRAI Syu-ichi, SUGIYAMA Yuki, SUZUKI Atsushi, OHNO Shigeo. Induction of MST/MLK2 mRNA by heat shock. 1998. 21. 551-551

Lectures and oral presentations (15)：

Basement membrane regulates spheroidal shape formation of the vertebrate eye lens
(Annual Meeting of the Molecular Biology Society of Japan 2020)
Cell rearrangement and shape change cooperatively drive lens cell movement to form spherical tissue
(International Conference on the Lens (ICL) 2019)
Cell rearrangement and shape change cooperatively drive lens cell movement to form a spherical tissue
(Molecular Biology Society of Japan Annual Meeting 2019)
Live-imaging of 4D dynamics of lens fibre cells
(International Zebrafish Conference 2019)
Live-imaging collective migration of lens fibre cells
(Association for Research in Vision and Ophthalmology (ARVO) annual meeting 2019)

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Work history (5)：

2017 - 2022 Okinawa Institute of Science and Technology (Japan) Staff Scientist
2008 - 2016 University of Sydney (Australia)
2006 - 2007 Yokohama City University School of Medicine (Japan) Postdoctoral fellow
2004 - 2006 University of Durham (UK) Research associate
2000 - 2003 Yokohama City University School of Medicine (Japan) Postdoctoral fellow

Awards (4)：

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