Kawabata Tsuyoshi

カワバタツヨシ | Kawabata Tsuyoshi

Affiliation and department：
Job title：助教

Research field (3)： Experimental pathology , Genetics , Cell biology

Research keywords (6)： DNA repair , tumorigenesis , Mutagenesis , Genome stability , Replication stress , Autophagy

Research theme for competitive and other funds (3)：

2023 - 2026 Determination of the mechanism and role of autophagy in starvation tolerance and tissue regeneration in newts.
2019 - 2023 Development and drug discovery for urolithiasis by integrated analysis of bio-repair mechanisms
2019 - 2022 オートファジーの異常がもたらすゲノム情報の破綻と発がん

Papers (31)：

Tsuyoshi Kawabata, Reiko Sekiya, Shinji Goto, Tao-Sheng Li. Chronic replication stress invokes mitochondria dysfunction via impaired parkin activity. Scientific reports. 2024. 14. 1. 7877-7877
Jose Norberto S Vargas, Maho Hamasaki, Tsuyoshi Kawabata, Richard J Youle, Tamotsu Yoshimori. The mechanisms and roles of selective autophagy in mammals. Nature reviews. Molecular cell biology. 2022
Lina Abdelghany, Tsuyoshi Kawabata, Shinji Goto, Keiichi Jingu, Tao-Sheng Li. Nicaraven induces programmed cell death by distinct mechanisms according to the expression levels of Bcl-2 and poly (ADP-ribose) glycohydrolase in cancer cells. Translational oncology. 2022. 26. 101548-101548
Tadashi Yamamuro, Shuhei Nakamura, Kyosuke Yanagawa, Ayaka Tokumura, Tsuyoshi Kawabata, Atsunori Fukuhara, Hirofumi Teranishi, Maho Hamasaki, Iichiro Shimomura, Tamotsu Yoshimori. Loss of RUBCN/rubicon in adipocytes mediates the upregulation of autophagy to promote the fasting response. Autophagy. 2022. 1-11
Gota Yoshida, Tsuyoshi Kawabata, Hyota Takamatsu, Shotaro Saita, Shuhei Nakamura, Keizo Nishikawa, Mari Fujiwara, Yusuke Enokidani, Tadashi Yamamuro, Keisuke Tabata, et al. Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis. Autophagy. 2022. 1-10

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MISC (8)：

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Books (2)：

オートファジー分子メカニズムの理解から病態の解明まで
南山堂 2018 ISBN:9784525134815
Mouse Genetics, Methods in molecular biology
Humana Press, New York, NY 2014 ISBN:9781493912155

Education (2)：

2002 - 2007 Saitama University Graduate School of Science and Engineering Department of Genetics
1998 - 2002 Saitama University Department of Science Regulation Biology

Work history (5)：

2017/07 - 現在 Nagasaki University Department of Stem Cell Biology, Atomic Bomb Disease Institute Assistant professor
2014/04 - 2017/06 Osaka University Graduate school of Medicine, Dept of Genetics Assistant professor
2012/04 - 2014/03 University of Minnesota Dept. of GCD JSPS Postdoctoral Fellow for Research Abroad
2010/10 - 2012/03 University of Minnesota Dept. of GCD Research Associate
2007/10 - 2010/09 University of Minnesota Dept. of GCD Postdoctoral fellow

Awards (1)：

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