Takaya Sakura

Affiliation and department：
Job title：助教

Research field (4)： Tumor biology , Cell biology , Molecular biology , Parasitology

Research theme for competitive and other funds (4)：

2022 - 2025 Molecular mechanisms of gliding motility in Plasmodium merozoites
2022 - 2025 Energy metabolism transition of gametocyte-genesis
2019 - 2022 Molecular mechanisms of gliding motility and erythrocyte invasion by Plasmodium falciparum
2019 - 2021 De novo biosynthesis of pyrimidine in tumor microenvironment.

Papers (30)：

Takaya Sakura, Ryuta Ishii, Eri Yoshida, Kiyoshi Kita, Teruhisa Kato, Daniel Ken Inaoka. Accelerating antimalarial drug discovery with a new high-throughput screen for fast-killing compounds. ACS Infectious Diseases. 2024
Ryuta Ishii, Takaya Sakura, Daniel Ken Inaoka, Fuyuki Tokumasu. Glycolytic enzymes form membrane-less condensates in the malaria parasite Plasmodium falciparum by sensing glucose levels. 2024
Junpei Fukumoto, Minako Yoshida, Suzumi M. Tokuoka, Eri Saki H. Hayakawa, Shinya Miyazaki, Takaya Sakura, Daniel Ken Inaoka, Kiyoshi Kita, Jiro Usukura, Hideo Shindou, et al. Pivotal roles of Plasmodium falciparum lysophospholipid acyltransferase 1 in cell cycle progression and cytostome internalization. 2024
直田紗希, Rajib Acharjee, 林下瑞希, 佐倉孝哉, 田山雄基, 濱野真二郎, 北潔, 河津信一郎, 稲岡ダニエル健. マンソン住血吸虫sulfite oxidaseの生化学的解析. 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [1P-235]
Pravitasari Normalita Eka, 佐倉孝哉, Ng'etich Japheth Kibet, 竹生田淳, 水上修作, 平山謙二, 武田弘資, 田中義正, 北潔, 稲岡ダニエル健. 長崎大学海洋微生物抽出物ライブラリーから単離されたマラリア原虫呼吸鎖阻害剤の作用メカニズム. 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [2P-187]

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MISC (5)：

Ryoma Kamikawa, Eriko Matsuo, Euki Yazaki, Michiru Tahara, Takaya Sakura, Kisaburo Nagamune, Yuji Inagaki. A snap shot of the gene replacement after endosymbiotic gene transfer: plastid GAPDH genes in the dinoflagellete Karenia brevis as a case study. Protist2014. 2014
Ryoma Kamikawa, Eriko Matsuo, Euki Yazaki, Michiru Tahara, Takaya Sakura, Kisaburo Nagamune, Yuji Inagaki. Cellular localization of evolutionally distinctive 'plastid-targeted' GAPDHs in Karenia brevis and K. mikimotoi. Integrated Microbial Biodiversity Program meeting, Canadian Institute for Advanced Research. 2014
永宗喜三郎, 松原立真, 田原美智留, 佐倉孝哉. 明日に向かってスベれ! 細胞運動獲得モデル:アピコンプレクサ類生物. 細胞工学. 2014. 33. 7. 774-776
松尾恵梨子, 神川龍馬, 矢崎裕規, 田原美智留, 佐倉孝哉, 永宗喜三郎, 稲垣祐司. Karenia属渦鞭毛藻における進化的起源の異なる葉緑体型GAPDHの進化と細胞内局在. 第15回進化学会ワークショップ. 2013
佐倉孝哉. 赤血球に寒イボを作るマシーン -マラリア原虫で見つかった新型分泌装置-. 蛋白質核酸酵素. 2009. 54. 13

Books (2)：

Lectures and oral presentations (23)：

High throughput screening identifies compounds with nanomolar antiplasmodial activity against the asexual stage parasites
(2024 ASTMH Annual Meeting 2024)
Accelerating antimalarial drug discovery with a high-throughput screening for fast-killing compounds
(2024 ASTMH Annual Meeting 2024)
Enzymatic kinetics of glycolysis enzymes in the asexual blood-stage malaria
Analysis of liquid-liquid phase separation in Plasmodium falciparum
(Molecular Approaches to Malaria (MAM) 2024)
Mechanism of action of an antimalarial compound isolated from Nagasaki University's marine microbial extracts:targeting mitochondrial electron transport chain
(2023)

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Education (3)：

Professional career (1)：

Work history (6)：

2024 - 現在長崎大学熱帯医学研究所感染生化学
2019 - 現在 Nagasaki University Institute of Tropical Medicine
2017 - 現在長崎大学大学院熱帯医学・グローバルヘルス研究科(兼任)
2016 - 2017 INSERM U1016, CNRS UMR8104, Institut Cochin, France
2014 - 2016 Center for Infection and Immunity of Lille, CNRS UMR8204, INSERM U1019, Institut Pasteur de Lille, France

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Association Membership(s) (4)：

JAPANESE SOCIETY OF TROPICAL MEDICINE , THE JAPANESE SOCIETY OF PARASITOLOGY , 日本バイオインフォマティクス学会 , ポルフィリン-ALA学会

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