Shizuko Kakinuma

カキヌマシヅコ | Shizuko Kakinuma

Research keywords (3)：ゲノム変異 , 発がんリスク , 放射線

Research theme for competitive and other funds (18)：

2021 - 2024 Development of Flow-Fish method for identifying cancer caused by radiation exposure
2021 - 2024 Elucidation of radiation carcinogenesis mechanism aiming at advanced evaluation of carcinogenesis risk due to exposure
2020 - 2023 リードスルー療法による家族性大腸腺腫症における腫瘍抑制効果に関する基礎的研究
2018 - 2020 宇宙放射線被ばくによる発がんリスクの推定; 病理およびゲノム変異解析から
2016 - 2018 宇宙放射線被ばくによる発がんリスクの推定:病理およびゲノム変異解析から

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Papers (182)：

Kenshi Suzuki, Chizuru Tsuruoka, Takamitsu Morioka, Hitomi Seo, Mari Ogawa, Ryosuke Kambe, Tatsuhiko Imaoka, Shizuko Kakinuma, Akihisa Takahashi. Combined effects of radiation and simulated microgravity on intestinal tumorigenesis in C3B6F1 Apc/+ mice. Life Sciences in Space Research. 2024. 41. 202-209
Megumi Sasatani, Yang Xi, Kazuhiro Daino, Atsuko Ishikawa, Yuji Masuda, Junko Kajimura, Jinlian Piao, Elena Karamfilova Zaharieva, Hiroaki Honda, Guanyu Zhou, et al. Rev1 overexpression accelerates N-methyl-N-nitrosourea (MNU)-induced thymic lymphoma by increasing mutagenesis. Cancer Science. 2024
Ryoko Semba, Takamitsu Morioka, Hiromi Yanagihara, Kenshi Suzuki, Hirotaka Tachibana, Takahiro Hamoya, Yoshiya Horimoto, Tatsuhiko Imaoka, Mitsue Saito, Shizuko Kakinuma, et al. Corrigendum to "Azithromycin induces read-through of the nonsense Apc allele and prevents intestinal tumorigenesis in C3B6F1 ApcMin/+ mice" [Biomed. Pharmacother. 164 (2023) 114968]. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023. 165. 115082-115082
Ryoko Semba, Takamitsu Morioka, Hiromi Yanagihara, Kenshi Suzuki, Hirotaka Tachibana, Takahiro Hamoya, Yoshiya Horimoto, Tatsuhiko Imaoka, Mitsue Saito, Shizuko Kakinuma, et al. Azithromycin induces read-through of the nonsense Apc allele and prevents intestinal tumorigenesis in C3B6F1 Apc/+ mice. Biomedicine & Pharmacotherapy. 2023. 164. 114968-114968
Yi Shang, Takamitsu Morioka, Kazuhiro Daino, Takafumi Nakayama, Mayumi Nishimura, Shizuko Kakinuma. Ionizing radiation promotes, whereas calorie restriction suppresses, NASH and hepatocellular carcinoma in mice. International journal of cancer. 2023

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MISC (222)：

井沢玄佳, 井沢玄佳, 小川真里, 品川まゆみ, 鶴岡千鶴, SHANG Yi, 砂押正章, 橘拓孝, 森岡孝満, 柿沼志津子, et al. Cellular senescence as a possible mechanism of radiation-induced breast cancer. アイソトープ・放射線研究発表会(Web). 2023. 60th
中村柚月, 中村柚月, 臺野和広, 石川敦子, 柿沼志津子, 高畠賢, 高畠賢, 井上一雅, 今岡達彦, 今岡達彦. Brca1変異ラットを用いた放射線関連乳がんのBrca1正常アリル不活性化の検証. がん予防学術大会プログラム・抄録集. 2023. 2023
臺野和広, 渡辺光, 石川敦子, 高畠賢, 高畠賢, 今岡達彦, 今岡達彦, 柿沼志津子. Chromosome rearrangements in radiation-induced tumors. Journal of Toxicological Sciences. 2023. 48. Supplement (CD-ROM)
永田健斗, 西村まゆみ, 臺野和広, 臺野和広, 飯塚大輔, 飯塚大輔, 西村由希子, 西村由希子, 服部佑哉, 渡邊立子, et al. Analysis of early cellular dynamics leading to radiation carcinogenesis in rat mammary gland. 日本癌学会学術総会抄録集(Web). 2023. 82nd
中村柚月, 中村柚月, 久保田丈, 臺野和広, 柿沼志津子, 福士政広, 福士政広, 井上一雅, 高畠賢, 高畠賢, et al. Analysis of carcinogenic mechanism of radiation-induced breast cancer in Brca1 heterozygous deficient rat model (Brca1^L63X/+ rat). アイソトープ・放射線研究発表会(Web). 2022. 59th

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Work history (1)：

2012/03 - 2024/03 東邦大学大学院理学研究科客員教授

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