Shizuko Kakinuma

カキヌマシヅコ | Shizuko Kakinuma

Research keywords (3)：ゲノム変異 , 発がんリスク , 放射線

Research theme for competitive and other funds (19)：

2024 - 2027 Elucidation of the carcinogenic mechanism by DNA recombination: Aiming to improve radiation carcinogenesis risk assessment
2021 - 2024 Development of Flow-Fish method for identifying cancer caused by radiation exposure
2021 - 2024 Elucidation of radiation carcinogenesis mechanism aiming at advanced evaluation of carcinogenesis risk due to exposure
2020 - 2023 リードスルー療法による家族性大腸腺腫症における腫瘍抑制効果に関する基礎的研究
2018 - 2020 宇宙放射線被ばくによる発がんリスクの推定; 病理およびゲノム変異解析から

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Papers (189)：

Atsuko Ishikawa, Yoshika Kin, Yutaka Yamada, Takamitsu Morioka, Mayumi Nishimura, Tatsuhiko Imaoka, Shizuko Kakinuma, Satoshi Tanaka, Rei Nakahira, Etsuko Kobayashi, et al. Sharing of data archive of radiation exposure animal experiments in QST/NIRS and IES. Radiation protection dosimetry. 2024. 200. 16-18. 1651-1655
Yukiko Nishimura, Daisuke Iizuka, Masaru Takabatake, Kazuhiro Daino, Mayumi Nishimura, Takamitsu Morioka, Yoshiya Shimada, Shizuko Kakinuma, Tatsuhiko Imaoka. Characterization of Molecular Subtypes of Rat Mammary Cancer and Their Association With Environmental Exposures. Anticancer research. 2024. 44. 10. 4261-4272
Tatsuhiko Imaoka, Satoshi Tanaka, Masanori Tomita, Kazutaka Doi, Megumi Sasatani, Keiji Suzuki, Yutaka Yamada, Shizuko Kakinuma, Michiaki Kai. Human-mouse comparison of the multistage nature of radiation carcinogenesis in a mathematical model. International journal of cancer. 2024. 155. 6. 1101-1111
Kento Nagata, Mayumi Nishimura, Kazuhiro Daino, Yukiko Nishimura, Yuya Hattori, Ritsuko Watanabe, Daisuke Iizuka, Akinari Yokoya, Keiji Suzuki, Shizuko Kakinuma, et al. Luminal progenitor and mature cells are more susceptible than basal cells to radiation-induced DNA double-strand breaks in rat mammary tissue. Journal of radiation research. 2024
Kentaro Ariyoshi, Tatsuhiko Imaoka, Yasushi Ohmachi, Yuka Ishida, Masahiro Uda, Mayumi Nishimura, Mayumi Shinagawa, Midori Yoshida, Toshiaki Ogiu, Mutsumi Kaminishi, et al. Influence of Age on Leukemia Mortality Associated with Exposure to γ rays and 2-MeV Fast Neutrons in Male C3H Mice. Radiation research. 2024

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MISC (222)：

井沢玄佳, 井沢玄佳, 小川真里, 品川まゆみ, 鶴岡千鶴, SHANG Yi, 砂押正章, 橘拓孝, 森岡孝満, 柿沼志津子, et al. Cellular senescence as a possible mechanism of radiation-induced breast cancer. アイソトープ・放射線研究発表会(Web). 2023. 60th
中村柚月, 中村柚月, 臺野和広, 石川敦子, 柿沼志津子, 高畠賢, 高畠賢, 井上一雅, 今岡達彦, 今岡達彦. Brca1変異ラットを用いた放射線関連乳がんのBrca1正常アリル不活性化の検証. がん予防学術大会プログラム・抄録集. 2023. 2023
臺野和広, 渡辺光, 石川敦子, 高畠賢, 高畠賢, 今岡達彦, 今岡達彦, 柿沼志津子. Chromosome rearrangements in radiation-induced tumors. Journal of Toxicological Sciences. 2023. 48. Supplement (CD-ROM)
永田健斗, 西村まゆみ, 臺野和広, 臺野和広, 飯塚大輔, 飯塚大輔, 西村由希子, 西村由希子, 服部佑哉, 渡邊立子, et al. Analysis of early cellular dynamics leading to radiation carcinogenesis in rat mammary gland. 日本癌学会学術総会抄録集(Web). 2023. 82nd
中村柚月, 中村柚月, 久保田丈, 臺野和広, 柿沼志津子, 福士政広, 福士政広, 井上一雅, 高畠賢, 高畠賢, et al. Analysis of carcinogenic mechanism of radiation-induced breast cancer in Brca1 heterozygous deficient rat model (Brca1^L63X/+ rat). アイソトープ・放射線研究発表会(Web). 2022. 59th

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Work history (1)：

2012/03 - 2024/03 東邦大学大学院理学研究科客員教授

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