Rchr
J-GLOBAL ID:201801018689018224   Update date: Jun. 26, 2024

Teruaki Fujishita

Teruaki Fujishita
Homepage URL  (1): https://www.pref.aichi.jp/cancer-center/ri/01bumon/07bunshi_byotai/03member.html#hujishita
Research field  (1): Experimental pathology
Research keywords  (3): 薬剤抵抗性 ,  モデルマウス ,  Colorectal cancer
Research theme for competitive and other funds  (10):
  • 2022 - 2025 Molecular mechanisms that maintain stemness in metastatic colorectal cancer
  • 2022 - 2025 The role and molecular mechanism of NAT10, an RNA-modifying enzyme, in colorectal cancer.
  • 2020 - 2023 大腸がん自然転移モデルを利用した転移関連遺伝子の探索
  • 2018 - 2022 Molecular mechanisms and preventive/therapeutic targets of colon cancer metastasis
  • 2016 - 2019 Elucidation of the interaction between tumor epithelial cells and stromal cells in acquiring resistance to molecular-targeted drugs
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Papers (46):
  • Yu Li, Teruaki Fujishita, Emi Mishiro-Sato, Yasushi Kojima, Yanqing Niu, Makoto Mark Taketo, Yuya Urano, Tomohisa Sakai, Atsushi Enomoto, Yoshihiro Nishida, et al. TGF-β signaling promotes desmoid tumor formation via CSRP2 upregulation. Cancer Science. 2023
  • Kojima, Y, Mishiro-Sato, E, Fujishita, T, Satoh, K, Kajino-Sakamoto, R, Oze, I, Nozawa, K, Narita, Y, Ogata, T, Matsuo, K, et al. Decreased liver B vitamin-related enzymes as a metabolic hallmark of cancer cachexia. Nat. Commun. 2023. 14. 1. 6246-6246
  • Teruaki Fujishita, Yasushi Kojima, Rie Kajino-Sakamoto, Emi Mishiro-Sato, Yasuhiro Shimizu, Waki Hosoda, Rui Yamaguchi, Makoto Mark. Taketo, Masahiro Aoki. The cAMP/PKA/CREB and TGF-β/SMAD4 pathways regulate stemness and metastatic potential in colorectal cancer cells. Cancer Research. 2022. 82. 22. 4179-4190
  • Hisanori Isomura, Ayumu Taguchi, Taisuke Kajino, Naoya Asai, Masahiro Nakatochi, Seiichi Kato, Keiko Suzuki, Kiyoshi Yanagisawa, Motoshi Suzuki, Teruaki Fujishita, et al. Conditional Ror1 knockout reveals crucial involvement in lung adenocarcinoma development and identifies novel HIF-1α regulator. Cancer Science. 2021. 112. 4. 1614-1623
  • Seisuke Tanigawa, Mitsugu Fujita, Chiami Moyama, Shota Ando, Hiromi Ii, Yasushi Kojima, Teruaki Fujishita, Masahiro Aoki, Hayato Takeuchi, Takumi Yamanaka, et al. Inhibition of Gli2 suppresses tumorigenicity in glioblastoma stem cells derived from a de novo murine brain cancer model. Cancer gene therapy. 2021. 28. 12. 1339-1352
more...
MISC (25):
  • 藤下晃章, 三城恵美, 武藤誠, 青木正博, 青木正博. The role of RhoC in colorectal cancer metastasis. 日本癌学会学術総会抄録集(Web). 2023. 82nd
  • 藤下晃章, 梶野リエ, 三城恵美, 武藤誠, 青木正博, 青木正博. Transposon-based screening of metastasis-related genes in a colorectal cancer mouse model. 日本癌学会学術総会抄録集(Web). 2022. 81st
  • 李宇, 李宇, 藤下晃章, 三城恵美, 武藤誠, 榎本篤, 西田佳弘, 青木正博, 青木正博. TGF-β signaling promotes desmoid tumor formation in a mouse model. 日本癌学会学術総会抄録集(Web). 2022. 81st
  • 小島康, 三城恵美, 藤下晃章, 梶野リエ, 曽我朋義, 武藤誠, 青木正博. がん悪液質の病態生理解明と治療戦略の基盤構築 マウスモデルを用いた網羅的解析. 愛知県がんセンター年報(Web). 2022. 58
  • 藤下晃章, 三城恵美, 梶野リエ, 新間秀一, 曽我朋義, 武藤誠, 青木正博. がんの発症・悪性化における微小環境の役割の解明 腸管腫瘍の悪性化におけるmTORC1経路の役割の解析. 愛知県がんセンター年報(Web). 2022. 58
more...
Lectures and oral presentations  (10):
  • Mechanism of synthetic lethality induced by MyD88 loss in intestinal tumor cells with Wnt pathway mutations
    (the 81st Annual Meeting of the Japanese Cancer Association 2022)
  • TGF-β signaling promotes desmoid tumor formation in a mouse model
    (the 81st Annual Meeting of the Japanese Cancer Association 2022)
  • Tumor microenvironment-related pathways critical for stemness and metastatic potential of colorectal cancer
    (the 81st Annual Meeting of the Japanese Cancer Association 2022)
  • Transposon-based screening of metastasis-related genes in a colorectal cancer mouse model
    (the 81st Annual Meeting of the Japanese Cancer Association 2022)
  • Identification of Metastasis-related Molecules Using a Mouse Model of Metastatic Colorectal Cancer
    (the 31st Annual Meeting of the Japanese Association for Metastatic Research 2022)
more...
Education (3):
  • 2003 - 2007 京都大学大学院 医学研究科 博士課程 生理系専攻
  • 2001 - 2003 Kyoto Pharmaceutical University
  • 1997 - 2001 Kyoto Pharmaceutical University Pharmaceutical Sciences Pharmacy
Work history (1):
  • 2016/04 - 2018/03 Aichi Cancer Center, Research Institute
Association Membership(s) (4):
THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  THE JAPANESE CANCER ASSOCIATION
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