Research theme for competitive and other funds (3):
2022 - 2025 小胞体標的マンノシダーゼ阻害剤の開発と細胞内糖鎖産生経路解析への応用
2021 - 2022 糖鎖封入リポソームを用いた細胞を反応場とした糖鎖プロセシング解析法の開発
選択的阻害剤を活用した糖タンパク質の分泌および分解経路の責任酵素同定
Papers (23):
Taiki Kuribara, Mitsuaki Hirose, Naoya Tajima, Kiichiro Totani. Chemical Study of High-Mannose-Type Glycan-Related Proteins to Understand Their Functions at the Molecular Level. Trends in Glycoscience and Glycotechnology. 2024. 36. 213. E94-E103
Mitsuaki Hirose, Yuto Nakamachi, Hasumi Muto, Akito Taira, Shinji Tanaka, Taiki Kuribara, Kiichiro Totani. Preparation of natural high-mannose-type oligosaccharides (Glc1Man9GlcNAc2) with the asparagine-glycine-threonine as consensus sequence from chicken egg yolk. Carbohydrate Research. 2024. 540. 109138-109138
Ruchio Usui, Akira Koizumi, Kyohei Nitta, Taiki Kuribara, Kiichiro Totani. Multisite Partial Glycosylation Approach for Preparation of Biologically Relevant Oligomannosyl Branches Contribute to Lectin Affinity Analysis. The Journal of Organic Chemistry. 2023
Taiki Kuribara, Kiichiro Totani. Oligomannose-Type Glycan Processing in the Endoplasmic Reticulum and Its Importance in Misfolding Diseases. Biology. 2022. 11. 2. 199-199
Yuichi Kawanobe, Naoya Kuragaki, Taro Tsubomura, Yasuomi Yamazaki, Taiki Kuribara, Kiichiro Totani. Mechanistic Study of Silyl-Assist Effect on 1,2- cis -α-Glucosylation. ChemistrySelect. 2022. 7. 1