Rchr
J-GLOBAL ID:201801018943664956
Update date: Jun. 24, 2024
Yasuhiro Shinkai
シンカイ ヤスヒロ | Yasuhiro Shinkai
Homepage URL (1):
http://www.md.tsukuba.ac.jp/chs/life_system/shinkai.htm
Research field (1):
Pharmaceuticals - health and biochemistry
Research keywords (3):
Sulfane sulfur
, Environmental electrophiles
, Metal
Research theme for competitive and other funds (2):
- 2022 - 2023 メタロチオネインのサルフェン硫黄を介したレドックス制御機構の解明
- 2020 - 2023 環境中親電子物質の解毒に働くサルフェン硫黄結合タンパク質の同定とその機能解析
Papers (83):
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Akiyama, Masahiro, Shinkai, Yasuhiro, Yamakawa, Hiroto, Kim, Yun-Gi, Kumagai, Yoshito. Potentiation of methylmercury toxicity by combined metal exposure: In vitro and in vivo models of a restricted metal exposome. Chemosphere. 2022. 299. 134374-134374
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Horai, Sawako, Abiko, Yumi, Unoki, Takamitsu, Shinkai, Yasuhiro, Akiyama, Masahiro, Nakata, Katsushi, Kunisue, Tatsuya, Kumagai, Yoshito. Concentrations of nucleophilic sulfur species in small Indian mongoose (Herpestes auropunctatus) in Okinawa, Japan. Chemosphere. 2022. 295. 133833-133833
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Liu, Jun, Kasai, Shuya, Tatara, Yota, Yamazaki, Hiromi, Mimura, Junsei, Mizuno, Seiya, Sugiyama, Fumihiro, Takahashi, Satoru, Sato, Tsubasa, Ozaki, Taku, et al. Inducible Systemic Gcn1 Deletion in Mice Leads to Transient Body Weight Loss upon Tamoxifen Treatment Associated with Decrease of Fat and Liver Glycogen Storage. International Journal of Molecular Sciences. 2022. 23. 6. 3201
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Unoki, Takamitsu, Akiyama, Masahiro, Shinkai, Yasuhiro, Kumagai, Yoshito, Fujimura, Masatake. Spatio-temporal distribution of reactive sulfur species during methylmercury exposure in the rat brain. The Journal of toxicological sciences. 2022. 47. 1. 31-37
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Takahashi,Musubu, Kubota,Ayaka, Fujie,Tomoya, Shinkai,Yasuhiro, Kumagai,Yoshito, Nakano,Tsuyoshi, Hara,Takato, Yamamoto,Chika, Kaji,Toshiyuki. Fibroblast Growth Factor-2 Upregulates Reactive Sulfur Species Production via ERK1/2 Signal-Mediated Cystathionine γ-Lyase Induction in Cultured Bovine Aortic Endothelial Cells. BPB Reports. 2021. 4. 6. 175-181
more...
Books (1):
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Intracellular Accumulation of Arsenic, Resulting in its Cytotoxicity and a Cellular Defense System Against Arsenic
2007
Lectures and oral presentations (61):
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限定メタルエキスポソームのモデル化:銅の複合曝露によるメチル水銀毒性の増強
(第49回日本毒性学会学術年会 2022)
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細胞外における大気中キノン化合物の不活性化に対するシステインの役割
(第49回日本毒性学会学術年会 2022)
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超硫黄タンパク質としての神経成長抑制因子(GIF/MT3) のレドックス制御
(第2回レドックスR&D戦略委員会 春のシンポジウム 最先端技 術が切り拓くレドックスバイオロジー 2022)
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鉛はPERK-ATF4経路の活性化によって血管内皮細胞の活性イオウ分子産生を促進させる
(メタルバイオサイエンス研究会2021 2021)
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サルフェン硫黄を介したメタロチオネイン-3のレドックス制御
(メタルバイオサイエンス研究会2021 2021)
more...
Professional career (1):
- Ph.D. (University of Tsukuba)
Committee career (6):
Awards (6):
Association Membership(s) (3):
The Japanese Society of Toxicology
, THE PHARMACEUTICAL SOCIETY OF JAPAN
, THE JAPANESE SOCIETY FOR HYGIENE
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