Tomita Hiroya

Affiliation and department：
Job title： Associate Professor
Other affiliations (1)：

Research field (3)： Biochemistry , Chemical biology , Applied microbiology

Research theme for competitive and other funds (10)：

2020 - 2025 Biosynthesis of sequence-regulated polyesters and analysis of synthetic mechanism
2022 - 2025 Directed evolution of sequence-regulationg polyhydroxyalkanoatae synthase for novel biopolyester biosynthesis
2022 - 2023 改変型重合酵素によるバイオプラスチック生合成の特性解析
2022 - 2022 Engineering of polyester synthase for production of the novel block copolymer
2021 - 2022 ポリヒドロキシアルカン酸合成酵素の構造に基づく機能改変

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Papers (29)：

Tomoya Kawakami, Hiroya Tomita, Phan Thi Hien, Ken'ichiro Matsumoto. Biosynthesis of high toughness poly(3-hydroxypropionate)-based block copolymers with poly(D-2-hydroxybutyrate) and poly(D-lactate) segments using evolved monomer sequence-regulating polyester synthase. Biopolymers. 2024
Yuka Hozumi, Shin-Ichi Hachisuka, Hiroya Tomita, Hiroshi Kikukawa, Ken'ichiro Matsumoto. Engineering of the Long-Main-Chain Monomer-Incorporating Polyhydroxyalkanoate Synthase PhaCAR for the Biosynthesis of Poly[(R)-3-hydroxybutyrate-co-6-hydroxyhexanoate]. Biomacromolecules. 2024
Hien Thi Phan, Shoko Furukawa, Koto Imai, Hiroya Tomita, Takuya Isono, Toshifumi Satoh, Ken'ichiro Matsumoto. Biosynthesis of High-Molecular-Weight Poly(D-lactate)-Containing Block Copolyesters Using Evolved Sequence-Regulating Polyhydroxyalkanoate Synthase PhaCAR. ACS Sustainable Chemistry & Engineering. 2023. 11. 30. 11123-11129
Kengo Yanagawa, Ayaka Kajikawa, Sayaka Sakakibara, Hiroyuki Kumeta, Hiroya Tomita, Ken'ichiro Matsumoto. Real-time NMR analysis of polyhydroxyalkanoate synthase reaction that synthesizes block copolymer comprising glycolate and 3-hydroxybutyrate. Biophysical chemistry. 2023. 296. 107001-107001
Kengo Yanagawa, Ayaka Kajikawa, Sayaka Sakakibara, Hiroyuki Kumeta, Hiroya Tomita, Ken'ichiro Matsumoto. Real-time NMR analysis of polyhydroxyalkanoate synthase reaction that synthesizes block copolymer comprising glycolate and 3-hydroxybutyrate. Biophysical Chemistry. 2023. 296. 107001-107001

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MISC (60)：

井口綾実, 蜂須賀真一, 菊川寛史, 冨田宏矢, 大井俊彦, 松本謙一郎. 2-ヒドロキシブタン酸ベースポリマーの微生物分解性の解析. 日本農芸化学会北海道支部学術講演会講演要旨集(Web). 2023. 2023
佐々木守, 佐藤圭悟, 柳川謙吾, 山本一輝, 蜂須賀真一, 菊川寛史, 冨田宏矢, 松本謙一郎. 中鎖ヒドロキシアルカン酸CoA化酵素AlkKの基質特異性のin vivo/in vitro解析. 日本農芸化学会北海道支部学術講演会講演要旨集(Web). 2023. 2023
穂積侑伽, 蜂須賀真一, 菊川寛史, 冨田宏矢, 松本謙一郎. 非天然長主鎖モノマーを含むポリヒドロキシアルカン酸生合成のための重合酵素PhaC_ARの進化工学的改変. 日本農芸化学会北海道支部学術講演会講演要旨集(Web). 2023. 2023
鶴廣太郎, 岡野憲司, 冨田宏矢, 宮崎健太郎, 本田孝祐, 本田孝祐. Development of enzyme evolution method that enables deletion, substitution, and insertion of codons. 日本生物工学会大会講演要旨集. 2023. 75th
村山大空, 宮崎健太郎, 冨田宏矢, 冨田宏矢, 本田孝祐, 本田孝祐. Development of novel Escherichia coli-Thermus thermophilus shuttle vectors. 日本生物工学会大会講演要旨集. 2023. 75th

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Lectures and oral presentations (4)：

Identification and application of nitro group-producing enzymes
(International Leading Research 1st On-line workshop for young researchers 2023)
Archaea and extremophiles
(Universitas Airlangga 2022)
Engineering of polyester synthase for production of the novel block copolymer
(2022)
有用ポリマー生産に向けた酵素工学的アプローチ
(第一回日本生物工学会北日本支部若手シンポジウム 2021)

Education (3)：

2011 - 2014 京都大学大学院工学研究科合成・生物化学専攻博士後期課程
2009 - 2011 京都大学大学院工学研究科合成・生物化学専攻修士課程
2005 - 2009 Kyoto University Faculty of Engineering School of Industrial Chemistry

Professional career (1)：

Work history (5)：

2022/10 - 現在 Osaka University International Center for Biotechnology Associate Professor
2022/11 - 2024/03 Hokkaido University Faculty of Engineering
2021/04 - 2022/09 北海道大学大学院工学研究院応用化学部門助教
2015/01 - 2021/03 東京大学大学院農学生命科学研究科特任研究員・学振特別研究員(PD)・特任助教
2012/04 - 2014/03 京都大学大学院工学研究科日本学術振興会特別研究員(DC2)

Committee career (1)：

Awards (2)：

Association Membership(s) (2)：

日本農芸化学会 , 日本生物工学会

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