Tomita Hiroya

Affiliation and department：
Job title： Associate Professor
Other affiliations (1)：

Hokkaido University Faculty of Engineering

Research field (3)： Biochemistry , Chemical biology , Applied microbiology

Research theme for competitive and other funds (10)：

2020 - 2025 Biosynthesis of sequence-regulated polyesters and analysis of synthetic mechanism
2022 - 2025 Directed evolution of sequence-regulationg polyhydroxyalkanoatae synthase for novel biopolyester biosynthesis
2022 - 2023 改変型重合酵素によるバイオプラスチック生合成の特性解析
2022 - 2022 Engineering of polyester synthase for production of the novel block copolymer
2021 - 2022 ポリヒドロキシアルカン酸合成酵素の構造に基づく機能改変

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Papers (27)：

Yuka Hozumi, Shin-Ichi Hachisuka, Hiroya Tomita, Hiroshi Kikukawa, Ken'ichiro Matsumoto. Engineering of the Long-Main-Chain Monomer-Incorporating Polyhydroxyalkanoate Synthase PhaCAR for the Biosynthesis of Poly[(R)-3-hydroxybutyrate-co-6-hydroxyhexanoate]. Biomacromolecules. 2024
Hien Thi Phan, Shoko Furukawa, Koto Imai, Hiroya Tomita, Takuya Isono, Toshifumi Satoh, Ken'ichiro Matsumoto. Biosynthesis of High-Molecular-Weight Poly(D-lactate)-Containing Block Copolyesters Using Evolved Sequence-Regulating Polyhydroxyalkanoate Synthase PhaCAR. ACS Sustainable Chemistry & Engineering. 2023. 11. 30. 11123-11129
Kengo Yanagawa, Ayaka Kajikawa, Sayaka Sakakibara, Hiroyuki Kumeta, Hiroya Tomita, Ken'ichiro Matsumoto. Real-time NMR analysis of polyhydroxyalkanoate synthase reaction that synthesizes block copolymer comprising glycolate and 3-hydroxybutyrate. Biophysical Chemistry. 2023. 296. 107001-107001
Keigo Satoh, Tomoya Kawakami, Nagi Isobe, Loïc Pasquier, Hiroya Tomita, Manfred Zinn, Ken’ichiro Matsumoto. Versatile aliphatic polyester biosynthesis system for producing random and block copolymers composed of 2-, 3-, 4-, 5-, and 6-hydroxyalkanoates using the sequence-regulating polyhydroxyalkanoate synthase PhaCAR. Microbial Cell Factories. 2022. 21. 1
Hien Thi Phan, Yumi Hosoe, Maureen Guex, Masayoshi Tomoi, Hiroya Tomita, Manfred Zinn, Ken’ichiro Matsumoto. Directed Evolution of Sequence-Regulating Polyhydroxyalkanoate Synthase to Synthesize a Medium-Chain-Length-Short-Chain-Length (MCL-SCL) Block Copolymer. Biomacromolecules. 2022. 23. 3. 1221-1231

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MISC (54)：

柳川謙吾, 梶川彩香, 榊原早也果, 久米田博之, 冨田宏矢, 冨田宏矢, 松本謙一郎. Real-time NMR Analysis of Polyhydroxyalkanoate Synthase Reaction That Synthesizes Block Copolymer of Glycolate and 3-Hydroxybutyrate. Journal of Environmental Biotechnology (Web). 2023. 23. 1
今井昂渡, 蜂須賀真一, 菊川寛史, 冨田宏矢, 松本謙一郎. ポリ乳酸セグメントを含む新規ブロック共重合体の微生物合成と物性制御. 日本栄養・食糧学会北海道支部大会講演要旨集. 2023. 53rd (CD-ROM)
富士航至, 梶川彩香, 冨田宏矢, 蜂須賀真一, 菊川寛史, 今村博臣, 松本謙一郎. ポリヒドロキシアルカン酸生合成過程におけるエネルギー代謝動態観察. 日本栄養・食糧学会北海道支部大会講演要旨集. 2023. 53rd (CD-ROM)
Yanagawa Kengo, Kajikawa Ayaka, Sakakibara Sayaka, Kumeta Hiroyuki, Tomita Hiroya, Matsumoto Ken’ichiro. Real-time NMR Analysis of Polyhydroxyalkanoate Synthase Reaction That Synthesizes Block Copolymer of Glycolate and 3-Hydroxybutyrate. Journal of Environmental Biotechnology. 2023. 23. 1. 39-43
山本一輝, 柳川謙吾, 冨田宏矢, 松本謙一郎. 改変型重合酵素を用いたグリコール酸ベースポリマー合成のin vitro解析. 日本農芸化学会東北支部大会プログラム・講演要旨集. 2022. 2022

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Lectures and oral presentations (4)：

Identification and application of nitro group-producing enzymes
(International Leading Research 1st On-line workshop for young researchers 2023)
Archaea and extremophiles
(Universitas Airlangga 2022)
Engineering of polyester synthase for production of the novel block copolymer
(2022)
有用ポリマー生産に向けた酵素工学的アプローチ
(第一回日本生物工学会北日本支部若手シンポジウム 2021)

Education (3)：

2011 - 2014 京都大学大学院工学研究科合成・生物化学専攻博士後期課程
2009 - 2011 京都大学大学院工学研究科合成・生物化学専攻修士課程
2005 - 2009 Kyoto University Faculty of Engineering School of Industrial Chemistry

Professional career (1)：

博士(工学) (京都大学)

Work history (5)：

2022/10 - 現在 Osaka University International Center for Biotechnology Associate Professor
2022/11 - 2024/03 Hokkaido University Faculty of Engineering
2021/04 - 2022/09 北海道大学大学院工学研究院応用化学部門助教
2015/01 - 2021/03 東京大学大学院農学生命科学研究科特任研究員・学振特別研究員(PD)・特任助教
2012/04 - 2014/03 京都大学大学院工学研究科日本学術振興会特別研究員(DC2)

Committee career (1)：

2023/06 - 現在日本生物工学会関西支部会計

Awards (2)：

2013/09 - International meeting on Thermophiles Best Poster Award
2012/12 - 極限環境生物学会優秀ポスター賞

Association Membership(s) (2)：

日本農芸化学会 , 日本生物工学会

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