Iseki Masanori

イセキマサノリ | Iseki Masanori

Affiliation and department：

Research field (1)： Immunology

Research theme for competitive and other funds (8)：

2024 - 2027 成人自己炎症性疾患VEXAS症候群の病態解明およびCas13を用いた革新的遺伝子治療の開発
2023 - 2026 Mechanisms of reciprocal regulation of immune diseases by EBI3-containing heterodimer cytokines
2019 - 2022 The investigation of the pathogenesis of TNF receptor-associated periodic syndrome
2019 - 2022 A novel regulatory mechanism for innate immune signals by ectoenzymes BST-1 and CD38
2018 - 2021 The role of SH3BP2 in the pathogenesis of systemic lupus eryhematosus

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Papers (29)：

Masanori Iseki, Shinya Hidano, Fujimi Kudo, Satoshi Takaki. Control of germinal center B cell survival and IgE production by an adaptor molecule containing PH and SH2 domains, Aps/Sh2b2. Scientific Reports. 2024. 14. 17767
Masanori Iseki, Yuma Sakamoto, Daiki Takezaki, Yoshihiro Matsuda, Mariko Inoue, Shin Morizane, Tomoyuki Mukai. Epstein-Barr virus induced 3 attributes to TLR7-mediated splenomegaly and bicytopenia. bioRxiv. 2024
Daiki Takezaki, Shin Morizane, Kenta Ikeda, Masanori Iseki, Yuma Sakamoto, Yoshio Kawakami, Taishi Hashiguchi, Yuka Shirakata, Sohji Nishina, Tomoyuki Mukai. Co-occurrence of non-alcoholic steatohepatitis exacerbates psoriasis associated with decreased adiponectin expression in a murine model. Frontiers in immunology. 2023. 14. 1214623-1214623
Takahiko Akagi, Sumie Hiramatsu-Asano, Kenta Ikeda, Hiroyasu Hirano, Shoko Tsuji, Ayano Yahagi, Masanori Iseki, Makoto Matsuyama, Tak W. Mak, Kazuhisa Nakano, et al. TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1. Frontiers in Immunology. 2022. 13
Kenta Ikeda, Shin Morizane, Takahiko Akagi, Sumie Hiramatsu-Asano, Kota Tachibana, Ayano Yahagi, Masanori Iseki, Hideaki Kaneto, Jun Wada, Katsuhiko Ishihara, et al. Obesity and Dyslipidemia Synergistically Exacerbate Psoriatic Skin Inflammation. International journal of molecular sciences. 2022. 23. 8

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MISC (11)：

竹崎大輝, 向井知之, 井関將典, 橋口太志, 白方有香, 森実真. 非アルコール性脂肪肝炎は乾癬モデルマウスの皮膚IL-23A遺伝子発現を増強する. 日本皮膚科学会雑誌. 2023. 133. 5. 1349-1349
向井知之, 池田賢太, 森実真, 赤木貴彦, 浅野澄恵, 立花宏太, 矢作綾野, 井関將典, 金藤秀明, 和田淳, et al. 肥満・高脂血症は相乗的に乾癬様皮疹を悪化する. 日本臨床免疫学会総会プログラム・抄録集. 2022. 50回. 99-99
石原克彦, 矢作綾野, 井関將典, 向井知之. リウマチ性疾患の基礎研究関節リウマチマウスモデルgp130F759の自然免疫獲得免疫移行期における滑膜B細胞抗原受容体のシングルセル解析. 日本リウマチ学会総会・学術集会プログラム・抄録集. 2022. 66回. 343-343
Mukai Tomoyuki, Akagi Takahiko, Asano Sumie, Yahagi Ayano, Iseki Masanori, Ishihara Katsuhiko, Morita Yoshitaka. Pathogenesis of rheumatic diseases 肥満と高脂血症は相乗的に乾癬性皮膚炎を増悪させる(Obesity and hyperlipidemia synergistically exacerbate psoriatic skin inflammation). 日本リウマチ学会総会・学術集会プログラム・抄録集. 2022. 66回. 560-560
Ishihara Katsuhiko, Yahagi Ayano, Iseki Masanori, Mukai Tomoyuki. マウス関節リウマチモデルgp130F759の自然免疫から獲得免疫への移行期における滑膜のシングルセルRNAシーケンシング(Single-cell RNA-sequencing of the synovium in gp130F759, a murine rheumatoid arthritis model, at the transitional phase from innate to acquired immunity). 日本免疫学会総会・学術集会記録. 2021. 50. Proceedings. 2-P

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Lectures and oral presentations (67)：

サイトカインコンポーネントEBI3はTLR7リガンド刺激による全身性炎症を促進する
(第45回日本炎症・再生医学会 2024)
大黄甘草湯の効き目は腸内細菌で決まる -食習慣による腸内細菌叢の変化と「証」との関わりを探る-
(第74回日本東洋医学会学術総会 2024)
Concomitant Nonalcoholic Steatohepatitis Worsens Psoriasis Associated with Decreased Adiponectin Expression in a Mouse Model
(The 52nd Annual Meeting of the Japanese Society for Immunology 2024)
The cytokine component Epstein-Barr virus induced 3 (EBI3) promotes systemic inflammation induced by TLR7 ligand
(The 52nd Annual Meeting of the Japanese Society for Immunology 2024)
非アルコール性脂肪性肝炎の併存はマウスモデルにおける乾癬を悪化させる
(第46回日本分子生物学会年会 2023)

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Committee career (1)：

2013 - 2016 日本免疫学会免疫ふしぎ未来実行委員会協力委員

Association Membership(s) (4)：

日本サイトメトリー学会 , Japan College of Rheumatology , The Molecular Biology Society of Japan (MBSJ) , The Japanese Society for Immunology (JSI)

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