Research keywords (3)：
Terpenoid
, Streptomyces
, intestinal bacterium
Research theme for competitive and other funds (9)：
2022 - 2025 新規C-C結合形成酵素と新規還元酵素による非天然型C-配糖体合成経路の構築
2021 - 2024 Elucidation and application of diverse catechin metabolism by microorganisms
2019 - 2022 Characterization of enzymes involved in C-glycosides metabolism
2016 - 2018 Turmeric degradation by microorganisms from soil
2017 - 2018 Study on the novel piperine metabolism
2014 - 2017 Microbial degradation of bioactive substance from turmeric
2014 - 2017 Studies on microbial degradation of a nitrogen-containing environmentally hazardous compound
2011 - 2016 Comprehensive elucidation and application of the function of enzymes involved in cleavage and synthesis of a carbon-nitrogen bond
2012 - 2015 Characterization of an N3 compound-degrading enzyme
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Papers (26)：
Yoshiteru, Hashimoto, Kana, Ishigami, Azam, Hassaninasab, Katsuhiro, Kishi, Takuto, Kumano, Michihiko, Kobayashi. Curcumin degradation in a soil microorganism: Screening and characterization of a beta-diketone hydrolase. J. Biol. Chem. 2024. 300. 9. 107647
Jian, Pu, Kumano, Takuto, Kimura, Mio, Kurisaki, Makoto, Hashimoto, Yoshiteru, Kobayashi, Michihiko. Biodegradation of the methylenedioxyphenyl group in piperine and its derivatives: discovery of a novel methylenetransferase in an actinomycete. Applied and Environmental Microbiology. 2023. 89. 11
Kumano, T, Hori, S, Watanabe, S, Terashita, Y, Yu, H. Y, Hashimoto, Y, Senda, T, Senda, M, Kobayashi, M. FAD-dependent C-glycoside-metabolizing enzymes in microorganisms: Screening, characterization, and crystal structure analysis. Proc. Natl. Acad. Sci. USA. 2021. 118. 40. e2106580118
Mori, T, Kumano, T, He, H, Watanabe, S, Senda, M, Moriya, T, Adachi, N, Hori, S, Terashita, Y, Kawasaki, M, et al. C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes. Nature communications. 2021. 12. 1. 12:6294-6294
Yoshiteru, Hashimoto, Ube, Yuko, Doi, Shiori, Kumano, Takuto, Kobayashi, Michihiko. Metal chaperone, NhpC, involved in the metallocenter biosynthesis of nitrile hydratase. The Journal of General and Applied Microbiology. 2020. 67. 1. 24-32
Masatoshi Yamada, Yoshiteru Hashimoto, Takuto Kumano, Seiya Tsujimura, Michihiko Kobayashi. New function of aldoxime dehydratase: Redox catalysis and the formation of an expected product (vol 12, e0175846, 2017). PLOS ONE. 2017. 12. 5
Books (1)：
構造多様性を創出する芳香族基質プレニルトランスフェラーゼに 関する基礎および応用研究
2010
Lectures and oral presentations (33)：
胡麻および胡椒由来代謝産物資化微生物の探索・機能解析
(日本微生物生態学会 第36回大会)
C-glycoside enzymatic reactions in soil and intestinal microorganisms
(3rd Japan-Switzerland-Germany Workshop on Biocatalysis and Bioprocess Development)
