- 2023 - 2026 Development of a method to predict and control pancreatic cancer therapeutic response by "RNA patterns" in exosomes.
- 2022 - 2025 Novel regenerative therapy for liver failure with skeletal myoblast cell sheet transplantation
- 2022 - 2025 直腸癌の個別的リスク評価を目的とした人工知能MRI解析アルゴリズムの確立
- 2020 - 2025 Maximum accuracy and application of diagnostic performance by integrated analysis of cancer exosome antigen and internal RNA information
- 2021 - 2024 膵がん幹細胞に特異的な細胞外小胞の殻と中身の情報による診断性能の最高化
- 2021 - 2024 高分子薬の有効化に寄与する癌微小環境改善薬の開発
- 2021 - 2024 Reconstruction and the analysis of tumor stroma using ex vivo tumor model
- 2021 - 2024 Analysis of molecular mechanisum of pancreatic cancer cell death and immune responce after carbon ion radiiation and its application to surgery
- 2021 - 2024 Establishment of personalized medicine for the dramatic improvement in the prognosis of pancreatic cancer patients
- 2021 - 2024 シングルセル解析を駆使した癌幹細胞の捕捉と新規治療法の開発
- 2020 - 2023 多領域検体・多層オミックス解析で多様性を凌駕する真の肝内胆管がん治療標的の同定
- 2019 - 2022 移植・再生医療に向けた肝・膵組織の三次元立体構築
- 2019 - 2022 新しいリキッドバイオプシー技術を活かした膵癌の不均一性・進化の理解とその治療攻略
- 2019 - 2022 Rubiconを介した膵癌治療抵抗性のメカニズム解明と新規治療法の開発
- 2019 - 2022 膵癌におけるケモカインを介したがん間質(CAF)との相互作用メカニズムの解明
- 2018 - 2022 国際共同研究によるメカノバイオロジーを応用した細胞外小胞診断のための基盤構築
- 2019 - 2021 細胞外小胞のRNAメチル化計測によるがんバイオマーカーの最高性能化と実用化
- 2018 - 2021 難治性胆道癌における腫瘍進展メカニズムの解析に基づく集学的治療法の開発と評価
- 2017 - 2020 抗癌剤耐性誘導のメカニズム解明とエピゲノム変化をターゲットとした治療法の構築
- 2017 - 2019 Establishment of Highly Intrahepatic Metastatic Cell Line of HCC by In Vivo Selection and Investigation of Mechanism by Integrated Microarray Analysis
- 2016 - 2019 The development of novel treatment for hepato-biliary-pancreatic cancer with target of cancer stroma
- 2016 - 2019 Clinical impact of viable circulating tumor cells (v-CTC) detection and PD-L1 expression on v-CTC in the patients with resectable pancreatic cancer
- 2016 - 2018 A non-invasive tool for detecting pancreatic tumor-bearing murine odor by C. elegans
- 2015 - 2018 Research on personalized medicine against treatment-resistant liver cancer from the viewpoint of epithelial-Mesenchymal Transition and hierarchical replication ability
- 2014 - 2017 Function analysis of exosome derived from hepatocellular carcinoma cells under hypoxia for tumor angiogenesis, invasion and metastasis
- 2013 - 2016 Establishment of pancreatic islet morphological model describing pathogenic mechanism of type 2 diabetes by human pancreatic histological analysis
- 2013 - 2016 Comprehensive characterization of next generation strategy to improve clinical islet transplantation
- 2013 - 2016 Novel therapeutic development with the target of cancer cell eradication against cancer stem cells
- 2013 - 2016 Investigation of microRNA interaction between pancreatic cancer cells and the stromal cells aiming to overcome the resistance to chemotherapeutic drugs.
- 2013 - 2016 The detection of viable human circulating tumor cellsin resectable pancreatic cancer
- 2013 - 2015 肝移植における抗ドナー特異抗体産生意義の解明と個別化免疫療法の探求
- 2013 - 2015 Identification of novel inducing factors pancreatic beta cells by iPS modified technology
- 2012 - 2015 Evaluation of the mechanism of liver regeneration focused on intracellular signal transduction and Non-coding RNA expression
- 2012 - 2015 Change of cancer and pericancerous tissue induced by inflammation, IL-6/TGF-beta crosstalk, in biliary tract cancers.
- 2011 - 2012 Noveltechnology for imuse cell induction.
- 2010 - 2012 Involvement of microRNA in the sensitivity prediction ofpreoperative chemoradiotherapy in pancreatic cancer
- 2010 - 2012 Correlation between expression of exocrine progenitor genes and cancer stem cells in pancreatic cancer.
- 2008 - 2010 肝胆膵領域の新規バイオマーカーの探索
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