Usui Michihiko

Affiliation and department：

Research field (4)： Medical biochemistry , Biomaterials , Biomedical engineering , Conservative dentistry and endodontics

Research keywords (7)： spheroid , Periodontal ligament cells , 歯周病検査キット , gingival epithelium , Osteoblast , Osteoclast , Periodontitis

Research theme for competitive and other funds (25)：

2021 - 2026 Application of drug discovery based on immunoreceptor-mediated regulation of osteoclastogenesis by glucan
2022 - 2025 歯根膜細胞スフェロイドの幹細胞性・骨分化能亢進のメカニズム解明
2019 - 2022 Application and molecular basis of spheroid culture to the deterioration of periodontal ligament cells due to frequent passage
2017 - 2022 Development of therapeutic approach and exploration of molecules activating the central and peripheral organ for the treatment of musculoskeletal disorders
2018 - 2021 Role of salivary hydrogen sulfide in the pathogenesis of periodontitis

2017 - 2021 The development of new treatment for gingival cancer considering bone resorption and cancer immunoediting

2017 - 2020 Attempt of the periodontal tissue regeneration by the combination of periodontal ligament cell spheroid and vascularization factor

2016 - 2019 Periodontal resgeneration using co-cultured spheroids of hPDLMSCs and HUVECs

2015 - 2018 Effects of traumatic occlusion on periodontal destruction in patients with chronic periodontitis

2015 - 2018 Role of apelin on mechanisms to improve state of periodontitis by physical activity and its application to preventive dentistry

2015 - 2017 Identification of a role of apelin in obesity and periodontitis patients

2015 - 2017 Application to the periodontium of the periodontal ligament cells spheroid sheet

2014 - 2017 Molecular mechanisms of nerve-vessel-bone network

2014 - 2016 Development of therapy for osteoradionecrosis using the activation of osteoblast and hematopoietic stem cell

2013 - 2016 The functional analysis of SOD2, antioxidantdefense in periodontal tissue

2011 - 2013 Functional analysis of melanocortin receptor agonists in bone metabolism and the possibility of clinical application for osteonecrosis of the jaw

2011 - 2012 Expression and function of RANKL in gingival epithelialum

2009 - 2011 Comprehensive gene analysis in junctional epithelium

2009 - 2010 The elucidation of effect of LPA on bone and periodontal tissue

2008 - 2010 Investigation for establishment of periodontal regenerative therapy using stem cells in cultured periodontal ligament cells

2007 - 2008 Injectable composite carrier for periodontal healing and regeneration

2007 - 2008 The function of tob2 in bone and periodontal tissue

2004 - 2005 四肢の発生における骨・軟骨制御因子の役割の解明

2003 - 2005 歯周組織におけるTobの役割

2004 - 2004 癌に対するインテグリン・オステオポンチン阻害分子の転移抑制とその制御機構

Show all

Papers (99)：

Rieko Yamanaka, Michihiko Usui, Kaoru Kobayashi, Satoru Onizuka, Shingo Kasai, Kotaro Sano, Shou Hironaka, Ryota Yamasaki, Shinji Yoshii, Tsuyoshi Sato, et al. Evaluation of a Novel Immunochromatographic Device for Detecting Porphyromonas gingivalis in Patients with Periodontal Disease. International journal of molecular sciences. 2024. 25. 15
Yuna Kajiwara-Nakagaki, Ai Orimoto, Kaori Kometani-Gunjigake, Chia-Chien Hsu, Chihiro Nakatomi, Michihiko Usui, Wataru Ariyoshi, Takashi Toyono, Kentaro Ono, Tatsuo Kawamoto. The Effects of Short-term Hypoxic on the Differentiation of Human Dental Pulp Stem Cells K4DT. The Journal of the Kyushu Dental Society. 2024. 78. 1-2. 12-20
臼井通彦. 歯肉上皮細胞の多彩な役割防御と破壊の二面性. 日本歯科保存学雑誌. 2024. 67. 1. 20-23
臼井通彦. 【歯根膜由来細胞シートによる歯周組織再生治療】歯周組織再生療法の変遷と治療技術の進展. Precision Medicine. 2024. 7. 1. 16-19
Masanori Iwasaki, Maki Inoue, Michihiko Usui, Wataru Ariyoshi, Keisuke Nakashima, Yoshie Nagai-Yoshioka, Tatsuji Nishihara. The association between trypsin-like protease activity in the oral cavity and kidney function in Japanese workers. Journal of clinical periodontology. 2023

ｍore...

MISC (91)：

山中理映子, 臼井通彦, 小林薫, 鬼塚理, 佐藤毅, 藤井航, 有吉渉, 笠井信吾, 佐野孝太朗, 中島啓介, et al. 歯肉縁下プラーク中Porphyromonas gingivalisを検出する新規イムノクロマト装置の評価. 日本歯周病学会会誌. 2024. 66. 秋季特別. 139-139
弘中祥, 鬼塚理, 佐野孝太朗, 岡裕一郎, 有吉渉, 臼井通彦, 中島啓介. ヒト歯根膜由来間葉系幹細胞のスフェロイド培養による幹細胞性維持機構の解明. 日本歯周病学会会誌. 2024. 66. 秋季特別. 141-141
中垣(梶原)優那, 中垣(梶原)優那, 折本愛, 郡司掛(米谷)香織, HSU Chia-Chien, 中富千尋, 臼井通彦, 有吉渉, 豊野孝, 小野堅太郎, et al. The Effects of Short-term Hypoxic on the Differentiation of Human Dental Pulp Stem Cells K4DT. 九州歯科学会雑誌(Web). 2024. 78. 1/2
弘中祥, 鬼塚理, 佐野孝太朗, 有吉渉, 臼井通彦, 中島啓介. スフェロイド培養による幹細胞性維持機構の解明. 九州歯科学会雑誌(Web). 2024. 78
佐藤毅, 臼井通彦. ロピニロールは歯周炎における好中球性炎症と歯槽骨吸収を抑制する. 日本歯周病学会会誌. 2023. 65. 秋季特別. 142-142

ｍore...

Books (11)：

2023 Regenerative Therapy Guidelines for Patients with Periodontal Disease
2023 ISBN:9784263456804
ザ・ペリオドントロジー = The periodontology
永末書店 2023 ISBN:9784816014215
新臨床研修歯科医ハンドブック
医歯薬出版 2020 ISBN:9784263458525
臨床歯周病学
医歯薬出版 2020 ISBN:9784263458440
歯科衛生学辞典
永末書店 2019 ISBN:9784816013683

ｍore...

Education (2)：

- 2003 Tokyo Medical and Dental University
- 1999 Tokyo Medical and Dental University Faculty of Dentistry School of Dentistry

Work history (5)：

2012/04 - 現在 Kyushu Dental College Dentistry
2007/04 - 2012/03 Showa University School of Dentistry, Department of Periodontology
2005/05 - 2007/03 University of Rochester Post doctoral fellow
2003/04 - 2005/03 日本学術振興会特別研究員
1999/04 - 2003/03 東京医科歯科大学第2保存(歯周病学)

Committee career (9)：

2023/04 - 現在日本歯科保存学会認定委員会
2021/04 - 現在日本歯周病学会国際交流委員会
2021/04 - 現在日本歯周病学会認定医委員会
2013/04 - 現在日本歯科保存学会評議員
2013/04 - 現在日本歯周病学会評議員

Show all

Awards (8)：

2024/10 - 日本歯周病学会学術賞
2023/06 - 日本歯科保存学会優秀論文賞(松風優秀論文賞)
2023/06 - 日本歯科保存学会学術賞
2021/05 - 日本歯周病学会教育賞
2007/08 - 第49回歯科基礎医学会優秀ポスター賞

Show all

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page