YUMOTO RYOKO

ユモトリョウコ | YUMOTO RYOKO

Affiliation and department：
Research theme for competitive and other funds (9)：

2015 - 2017 Study on the mechanism of epithelial-mesenchymal transition as a cause of drug-induced lung injury, and development of the strategy for preventing the injury
2012 - 2014 Analysis of the drug-induced lung toxicity in relation to transdifferentiation of type II cells into type I cells and epithelial-mesenchymal transition
2011 - 2013 Analysis of low temperature tolerance of membrane transporters and development of pan-transporter inhibitors
2010 - 2013 Establishment of a new alveolar epithelial cell model by gene transfection and its application to the study on drug transport and toxicity in the lungs
2009 - 2011 Study on the transportsome for ribavirin uptake in human erythrocyte membrane

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Papers (146)：

Takano, Mikihisa, Kuriyama, Shiori, Kameda, Nanako, Kawami, Masashi, Yumoto, Ryoko. Effect of Corticosteroids on Peptide Transporter 2 Function and Induction of Innate Immune Response by Bacterial Peptides in Alveolar Epithelial Cells. BIOLOGICAL & PHARMACEUTICAL BULLETIN. 2022. 45. 2. 213-219
Kawami, Masashi, Yumoto, Ryoko, Takano, Mikihisa. Preventive approach against drug-induced pulmonary fibrosis through the suppression of epithelial-mesenchymal transition. BIOCELL. 2022. 46. 8. 1861-1865
Kawami, Masashi, Takenaka, Shinnosuke, Akai, Mizuki, Yumoto, Ryoko, Takano, Mikihisa. Characterization of miR-34a-Induced Epithelial-Mesenchymal Transition in Non-Small Lung Cancer Cells Focusing on p53. BIOMOLECULES. 2021. 11. 12
Kawami, Masashi, Takenaka, Shinnosuke, Kadekaru, Yuri, Akai, Mizuki, Konaka, Takashi, Yumoto, Ryoko, Takano, Mikihisa. Evaluation on epithelial-mesenchymal state and microRNAs focusing on isolated alveolar epithelial cells from bleomycin injured rat lung. TOXICOLOGY. 2021. 461
Baba, S., Yumoto, R., Kawami, M., Takano, M. Functional expression of equilibrative and concentrative nucleoside transporters in alveolar epithelial cells. PHARMAZIE. 2021. 76. 9. 416-421

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Lectures and oral presentations (141)：

抗がん剤による抗がん効果および上皮間葉転換におけるp53の役割解析
(日本薬学会第142年会 2022)
肺胞上皮細胞の形質に及ぼす高濃度グルコースの影響解析
(日本薬学会第142年会 2022)
p53に着目した非小細胞肺がん細胞株におけるmiR-34a誘発性上皮間葉転換
(日本薬学会第142年会 2022)
Mechanism of the inhibitory effect of inhaled corticosteroids on peptide transporter 2 function in human alveolar epithelial cells
(日本薬物動態学会第36年会 2021)
Effect of 2-deoxy-D-glucose on transforming growth factor-β1-induced epithelialmesenchymal transition in alveolar epithelium
(日本薬物動態学会第36年会 2021)

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Work history (9)：

2015/05/01 - 2019/03/31 Hiroshima University Institute of Biomedical & Health Sciences Associated Professor
2014/04/01 - 2015/04/30 Hiroshima University Institute of Biomedical & Health Sciences Lecturer
2012/04/01 - 2014/03/31 Hiroshima University Institute of Biomedical & Health Sciences Assistant Professor
2007/04/01 - 2012/03/31 Hiroshima University Graduate School of Biomedical Sciences Assistant Professor
2007/04/01 - 2012/03/31 Hiroshima University Graduate School of Biomedical Sciences Assistant Professor

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