Rchr
J-GLOBAL ID:201801020065287209   Update date: Jun. 13, 2024

Negishi Yasuyuki

ネギシ ヤスユキ | Negishi Yasuyuki
Affiliation and department:
Job title: Associate Professor
Other affiliations (2):
  • Nippon Medical School  Department of Obstetrics and Gynecology 
  • Nihon University  Department of Legal Medicine 
Research field  (3): Immunology ,  Immunology ,  Obstetrics and gynecology
Research keywords  (7): Preterm birth ,  Osteoimmunology ,  Obstetrics and Gynecology ,  Invariant natural killer T cells ,  Dendritic cells ,  Innate Immunity ,  Reproductive Immunology
Research theme for competitive and other funds  (17):
  • 2024 - 2028 内在性ウイルス異常は妊娠高血圧症を誘発するか-胎盤エクソソームのオミクス解析
  • 2024 - 2028 抗炎症をターゲットとした新たな免疫学的早産治療戦略への模索
  • 2022 - 2026 自然免疫を標的とした新たな閉経後骨粗鬆症メカニズム解析と発症予防・治療薬の開発
  • 2022 - 2026 新規治療法開発を指向した子宮内膜症におけるアラーミンとその受容体の免疫学的解析
  • 2022 - 2026 周産期の無菌性炎症と胎児発育不全ー成人生活習慣病との接点を探るー
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Papers (39):
  • Go Ichikawa, Yasuyuki Negishi, Fumihisa Chishima, Shunji Suzuki. Kikuchi-Fujimoto disease during early pregnancy. Journal of Obstetrics and Gynaecology Research. 2024
  • Syunya Noguchi, Sadayuki Ohkura, Yasuyuki Negishi, Shohei Tozawa, Takami Takizawa, Rimpei Morita, Hironori Takahashi, Akihide Ohkuchi, Toshihiro Takizawa. Cytoplasmic and nuclear DROSHA in human villous trophoblasts. Journal of Reproductive Immunology. 2024. 162. 104189-104189
  • Tatsunori Shiraishi, Mariko Ikeda, Takami Watanabe, Yasuyuki Negishi, Go Ichikawa, Hanako Kaseki, Shigeo Akira, Rimpei Morita, Shunji Suzuki. Downregulation of pattern recognition receptors on macrophages involved in aggravation of endometriosis. American Journal of Reproductive Immunology. 2024
  • Syunya Noguchi, Sadayuki Okura, Yasuyuki Negishi, Rimpei Morita, Akihide Ohkuchi, Hironori Takahashi, Toshihiro Takizawa. Localization of DROSHA in the trophoblast cell line BeWo infected with sindbis virus. Placenta. 2023. 141. 106-106
  • Toshihiro Takizawa, Syunya Noguchi, Sadayuki Okura, Yasuyuki Negishi, Rimpei Morita, Akihide Ohkuchi, Hironori Takahashi. Analysis of RNAs that bind to DROSHA expressed in the placental trophoblast. Placenta. 2023. 141. 100-100
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MISC (52):
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Books (6):
  • 妊娠と免疫・感染防御機構(総論)
    2024
  • 早産と妊娠高血圧腎症:病因・病態生理ー私はこうみる、無菌性炎症の観点から
    2022
  • 着床、妊娠の維持、分娩にかかわる自然免疫の多彩な役割
    2020
  • 基礎と臨床の両側面からみた胎盤学
    メジカルビュー社 2019
  • 実践生殖免疫学
    中外医学社 2018
more...
Lectures and oral presentations  (100):
  • 炎症性サイトカインIL-18による感染性早産の防止メカニズム
    (第40回日本産婦人科感染症学会学術集会 2024)
  • 感染・非感染に起因する流早産-炎症の役割とその功罪
    (第40回日本産婦人科感染症学会学術集会 2024)
  • IL-18: A pivotal player bridging between uterine immunity and placental formation
    (The 43rd Annual Meeting of the American Society for Reproductive Immunology 2024)
  • Aggravation of endometrial ovarian cyst involves the suppression of macrophage activity
    (The 43rd Annual Meeting of the American Society for Reproductive Immunology 2024)
  • Critical role of innate immunity in chorioamnionitis-independent preterm birth
    (The 76th Annual Congress of the Japan Society of Obstetrics and Gynecology 2024)
more...
Education (4):
  • 2006 - 2012 Nippon Medical School Department of Microbiology and Immunology
  • 1996 - 2002 Nippon Medical School
  • 1993 - 1995 Tokyo Metropolitan University Graduate School of Science Department of Physics
  • 1989 - 1993 Tokyo Metropolitan University Department of Physics
Professional career (2):
  • 博士(医学) (日本医科大学)
  • 修士(理学) (東京都立大学)
Work history (9):
  • 2022/11 - 現在 Nihon University Department of Legal Medicine
  • 2020/10 - 現在 Nippon Medical School Department of Microbiology and Immunology Associate Professor
  • 2018/04 - 2020/09 Nippon Medical School Department of Microbiology and Immunology Senior Assistant Profrssor
  • 2012/09 - 2018/03 Nippon Medical Scool Department of Microbiology and Immunology Assistant Professor
  • 2010/10 - 2012/08 Tokyo Rinkai Hospital Department of Obstetrics and Gynecology
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Committee career (3):
  • 2023/04 - 現在 Japan Placenta Association 評議員
  • 2022/11 - 現在 Japan Society for Immunology of Reproduction Director
  • 2015/11 - 2022/11 評議員
Awards (10):
  • 2021/10 - Japanese Society of Clinical Immunology 未来賞
  • 2020/10 - SUGIYAMA MEMORIAL FOUNDATION Grand Prize Distribution of dendritic cells in the septate uterus: an immunological perspective.
  • 2019/11 - 第27回日本胎盤学会 学会賞(相馬賞) 絨毛膜羊膜炎を伴わない原因不明早産の免疫学的解析-無菌性炎症からのアプローチ
  • 2018/11 - 33rd Annual Meeting of Japan Society for Immunology of Reproduction Award of JSIR Adoptive transfer of dendritic cells and invariant natural killer T cells activated by α-galactosylceramide directly induce murine pregnancy loss
  • 2017/12 - 32nd Annual Meeting of Japan Society for Immunology of Reproduction Award of JSIR Role of innate immune cells in preterm birth and miscarriages induced by sterile inflammation in mice and humans
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Association Membership(s) (12):
日本早産学会 ,  Japanese Society of Legal Medicine ,  Japan Society of Osteoimmunology ,  International Society for Immunology of Reproduction ,  The Japan Society of Clinical Immunology ,  Japan Placenta Association ,  The American Society for Reproductive Immunology ,  JAPAN SOCIETY FOR IMMUNOLOGY OF REPRODUCTION ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  JAPAN SOCIETY OF PERINATAL AND NEONATAL MEDICINE ,  JAPAN SOCIETY FOR THE STUDY OF HYPERTENSION IN PREGNANCY ,  JAPAN SOCIETY OF OBSTETRICS AND GYNECOLOGY
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