Yasuhara Takaaki

ヤスハラタカアキ | Yasuhara Takaaki

Affiliation and department：
Job title： Professor
Homepage URL (2)： https://www.rbc.kyoto-u.ac.jp/genome_stress/ , https://www.rbc.kyoto-u.ac.jp/genome_stress/en/

Research field (4)： Genomics , Tumor biology , Radiology , Environmental effects of radiation

Research keywords (6)： DNA damage response , DNA repair , Genome stability , Transcription , Condensate , Senescence

Research theme for competitive and other funds (10)：

2022 - 2026 Age-related changes in germline cells that cause chromosome translocations
2021 - 2026 Investigation of the new factors regulating transcription- associated DNA double-strand break repair
2021 - 2025 全ゲノム領域に共通した正確なDNA修復を保証するDSB修復経路選択機構の研究
2023 - 2025 Genome instability induced by spatial positions in the nucleus
2022 - 2024 A strategy to transform genomic organization and change the gene expression pattern via controlling nucleolar condensates

Show all

Papers (22)：

Peter W.T. LEE, Tatsuya SUWA, Minoru KOBAYASHI, Hui YANG, Lina R. KOSEKI, Satoshi TAKEUCHI, Christalle C.T. CHOW, Takaaki YASUHARA, Hiroshi HARADA. Hypoxia- and Postirradiation Reoxygenation-induced HMHA1/ARHGAP45 expression contributes to cancer cell invasion in a HIF-dependent manner. British Journal of Cancer. 2024. In press
Motohiro Yamauchi, Reona Kato, Takaaki Yasuhara, Yuki Uchihara, Miyako Hirakawa, Kie Ozaki, Yu Abe, Hiroki Shibata, Reika Kawabata-Iwakawa, Aizhan Shakayeva, et al. Involvement of the splicing factor SART1 in the BRCA1-dependent homologous recombination repair of DNA double-strand breaks. 2023
Taichi Igarashi, Marianne Mazevet, Takaaki Yasuhara, Kimiyoshi Yano, Akifumi Mochizuki, Makoto Nishino, Tatsuya Yoshida, Yukihiro Yoshida, Nobuhiko Takamatsu, Akihide Yoshimi, et al. An ATR-PrimPol pathway confers tolerance to oncogenic KRAS-induced and heterochromatin-associated replication stress. Nature Communications. 2023. 14. 4991
Takaaki Yasuhara, Yu-Hang Xing, Nicholas C. Bauer, Lukuo Lee, Rui Dong, Tribhuwan Yadav, Roy J. Soberman, Miguel N. Rivera, Lee Zou. Condensates induced by transcription inhibition localize active chromatin to nucleoli. Molecular Cell. 2022. 82. 15. 2738-2753
Yuki Uchihara, Tiara Bunga Mayang Permata, Hiro Sato, Reika Kawabata-Iwakawa, Sayako Katada, Wenchao Gu, Sangeeta Kakoti, Motohiro Yamauchi, Reona Kato, Soehartati Gondhowiardjo, et al. DNA damage promotes HLA class I presentation by stimulating a pioneer round of translation-associated antigen production. Molecular Cell. 2022. 82. 14. 2557-2570

ｍore...

Education (2)：

2011 - 2015 The University of Tokyo Graduate School of Medicine
2007 - 2011 The University of Tokyo The Faculty of Medicine

Professional career (1)：

PhD (Medicine) (The University of Tokyo)

Work history (7)：

2023/07 - 現在 Kyoto University Graduate School of Biostudies Professor
2023/04 - 2023/06 The University of Tokyo Isotope Science Center Project Lecturer
2021/10 - 2023/03 The University of Tokyo Graduate School of Medicine Center for Disease Biology and Integrative Medicine Assistant Professor
2018/06 - 2021/10 Massachusetts General Hospital Cancer Center Research Fellow
2018/06 - 2020/05 Japan Society for the Promotion of Science JSPS Overseas Research Fellow

Show all

Awards (8)：

2023/05 - Asian Young Scientist Fellowship 2023
2023/04 - The Minister of Education, Culture, Sports, Science and Technology The Young Scientists' Award, The Commendation for Science and Technology
2018/06 - Japan Society for the Promotion of Science Overseas Research Fellowships
2015/12 - The Molecular Biology Society of Japan Best Presenter Award
2015/10 - Young Radiation Biologists’ Association of Japan Best Paper Award

Show all

Association Membership(s) (2)：

THE JAPANESE RADIATION RESEARCH SOCIETY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page