Rchr
J-GLOBAL ID：201801020236689432   Update date: Jun. 03, 2024

Shuhei Sakakibara

サカキバラ シュウヘイ | Shuhei Sakakibara
Affiliation and department：
Jikei University of Health Care Sciences Graduate School of Medical Safety Management

About Jikei University of Health Care Sciences Graduate School of Medical Safety Management


Job title： Associate Professor
Other affiliations (1)：
  • Osaka University  WPI Immunology Frontier Research Center   Visiting Associate Professor
Research field  (1)： Immunology
Research keywords  (4)： Systemic lupus erythematosus ,  Allergy ,  Autoimmune Diseases ,  Immunology
Research theme for competitive and other funds  (9)：
  • 2020 - 2023 Development, validation and application of machine learning system for TCR epitope prediction
  • 2019 - 2022 全身性エリテマトーデスにおける抗DNA B細胞の親和性増大とその制御
  • 2020 - 2021 公益財団法人 持田記念医学薬学振興財団 研究助成金 「好酸球副鼻腔炎における病原性T 細胞の同定と性状解析」
  • 2019 - 2021 公益財団法人 武田医学振興財団 医学系研究助成 「全身性エリテマトーデスにおけるdsDNA反応性B細胞の親和性成熟機構の解明」
  • 2016 - 2019 体細胞超変異による自己反応性B細胞出現モデルの構築と末梢性B細胞自己寛容の解明
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Papers (48)：
  • Dianita S. Saputri, Hendra S. Ismanto, Dendi K. Nugraha, Zichang Xu, Yasuhiko Horiguchi, Shuhei Sakakibara, Daron M. Standley. Deciphering the antigen specificities of antibodies by clustering their complementarity determining region sequences. mSystems. 2023
  • Chao-Yuan Tsai, Shuhei Sakakibara, Yu-Diao Kuan, Hiroko Omori, Maruwa Ali El Hussien, Daisuke Okuzaki, Shiou-Ling Lu, Takeshi Noda, Keisuke Tabata, Shuhei Nakamura, et al. Opposing roles of RUBCN isoforms in autophagy and memory B cell generation. Science signaling. 2023. 16. 803. eade3599
  • Ryuya Edahiro, Yuya Shirai, Yusuke Takeshima, Shuhei Sakakibara, Yuta Yamaguchi, Teruaki Murakami, Takayoshi Morita, Yasuhiro Kato, Yu-Chen Liu, Daisuke Motooka, et al. Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity. Nature genetics. 2023. 55. 5. 753-767
  • Masakazu Ishikawa, Yuki Shimada, Tatsuhiko Ozono, Hisatake Matsumoto, Hiroshi Ogura, Keigo Kihara, Hideki Mochizuki, Tatsusada Okuno, Shuhei Sakakibara, Makoto Kinoshita, et al. Single-cell RNA-seq analysis identifies distinct myeloid cells in a case with encephalitis temporally associated with COVID-19 vaccination. Frontiers in Immunology. 2023. 14
  • Yu-Diao Kuan, Chao-Yuan Tsai, Shuhei Sakakibara, Daron M Standley, Hitoshi Kikutaniuan. External stimulation induces the secretion of autophagosome-like vesicles by B cells. Autophagy Reports. 2023. 2. 1
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MISC (13)：
  • 武田和也, 春名壯一郎, 榊原修平. アレルギー性真菌性鼻副鼻腔炎における炎症局所IgE産生:クローンレベルの特徴から理解する病態生理. 臨床免疫・アレルギー科. 2024. 81. 3. 269-273
  • 伊藤 弘, 石川 昌和, 吉村 旬平, 劉 祐誠, 松本 寿健, 杉原 文徳, 榊原 修平, 奥崎 大介, 平田 陽彦, 小倉 裕司, et al. RNA解析を用いたCOVID-19によるARDSの病態解明. 日本集中治療医学会雑誌. 2023. 30. Suppl.1. S586-S586
  • 武田和也, 春名壮一郎, 菊谷仁, 榊原修平. アレルギー性副鼻腔炎と防御性粘膜免疫のアレルギー転換. 臨床免疫・アレルギー科. 2023. 79. 3. 312-316
  • 石川昌和, 伊藤弘, LIU Yu-Chen, 吉村旬平, 榊原修平, 小倉裕司, 織田順, 松本寿健, 奥崎大介. Single cell RNA-seq of Neutrophils from Severe COVID-19 Patients. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
  • Shuhei Sakakibara, Kazuya Takeda, Marwa Ali El-Hussien, Hitoshi Kikutani. Production of IgE antibodies broadly cross-reactive to cell wall polysaccharides of multiple fungi in nasal mucosa of patients with allergic fungal rhinosinusitis. The 50th Annual Meeting of the Japanese Society of Immunlogy. 2021
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Education (3)：
  • 2001 - 2005 Osaka University Graduate School of Medicine
  • 1999 - 2001 Osaka University Graduate School of Medicine
  • 1995 - 1999 Osaka City University Faculty of Engineering Department of Applied Chemistry and Bioengineering,
Professional career (1)：
  • 博士 (大阪大学)
Work history (9)：
  • 2023/04 - 現在 Jikei University of Health Care Sciences Graduate School of Medical Safety Management Associate Professor
  • 2022/04 - 2023/03 Osaka University WPI Immunology Frontier Research Center Specially-appointed Assistant Professor (Part-time)
  • 2019/04 - 2022/03 Osaka University Immunology Frontier Research Center Endowed Chair Associate Professor
  • 2016/04 - 2019/03 Osaka University Immunology Frontier Research Center Endowed Chair Assistant Professor
  • 2011/06 - 2016/03 Osaka University Research Institute for Microbial Diseases Assistant Professor
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Awards (3)：
  • 2015/11 - The Japanese Society for Immunology Best Presentation Award "Antigen-specific maturation of anti-nuclear antibodies in systemic lupus erythematosus"
  • 2009 - JSPS 海外特別研究員 (NIH)
  • 2003 - JSPS 特別研究員奨励費 (学振DC2) カポシ肉腫関連ヘルペスウイルス潜伏感染機構の解明とその制御
Association Membership(s) (4)：
Japanese Society for Safety Education Research in Healthcare ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  The Japanese Society of Virology
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