Yamashiro Takahiro

ヤマシロタカヒロ | Yamashiro Takahiro

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Clinical pharmacy

Research keywords (2)：トランスポーター , 薬物動態

Research theme for competitive and other funds (7)：

2023 - 2026 新規コリントランスポーター類の分子機能と生理的及び薬物動態的役割
2023 - 2026 Elucidation of substrate recognition mechanism of SLC19A3 to establish the molecular basis for medical applications
2022 - 2025 Elucidation of pyridoxine kinetics mediated by crosstalk between a novel pyridoxine transporter and ion channels/transporters
2020 - 2023 新規ポリアミントランスポーターの機能及び生理的役割の解明
2020 - 2023 Elucidation of molecular mechanism that triggers onset of gout from hyperuricemia

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Papers (12)：

Shogo Akino, Tomoya Yasujima, Rei Shibutani, Takahiro Yamashiro, Hiroaki Yuasa. Involvement of Proton-Coupled SLC49A4-Mediated Transport in the Export of Lysosomally Trapped Pyrilamine. Drug Metabolism and Disposition. 2024. 52. 1. 19-25
Shogo Akino, Tomoya Yasujima, Takahiro Yamashiro, Hiroaki Yuasa. Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H+-driven lysosomal pyridoxine exporter. Life science alliance. 2023. 6. 2. e202201629
Kohei Miyake, Tomoya Yasujima, Syunsuke Takahashi, Takahiro Yamashiro, Hiroaki Yuasa. Identification of the amino acid residues involved in the species-dependent differences in the pyridoxine transport function of SLC19A3. Journal of Biological Chemistry. 2022. 298. 8. 102161-102161
Takahiro Yamashiro, Tomoya Yasujima, Hiroaki Yuasa. Animal species differences in the pyridoxine transport function of SLC19A3: Absence of Slc19a3-mediated pyridoxine uptake in the rat small intestine. Drug Metabolism and Pharmacokinetics. 2022. 44. 100456-100456
Yutaro Shinoda, Takahiro Yamashiro, Akira Hosooka, Tomoya Yasujima, Hiroaki Yuasa. Functional characterization of human organic anion transporter 10 (OAT10/SLC22A13) as an orotate transporter. Drug Metabolism and Pharmacokinetics. 2022. 43. 100443-100443

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MISC (3)：

Takahiro Yamashiro, Tomoya Yasujima, Kinya Ohta, Katsuhisa Inoue, Hiroaki Yuasa. IDENTIFICATION OF THE AMINO ACID RESIDUE RESPONSIBLE FOR THE FLAVONOID SENSITIVITY OF HUMAN PROTON-COUPLED FOLATE TRANSPORTER. DRUG METABOLISM AND PHARMACOKINETICS. 2018. 33. 1. S20-S20
Hiroaki Yuasa, Mai Furumiya, Katsuhisa Inoue, Chihiro Nishijima, Takahiro Yamashiro, Kinya Ohta, Yayoi Hayashi. SUSTAINED INHIBITORY EFFECT OF MYRICETIN ON FOLATE TRANSPORT BY PROTON-COUPLED FOLATE TRANSPORTER. DRUG METABOLISM REVIEWS. 2015. 47. 259-259
Takahiro Yamashiro, Kinya Ohta, Katsuhisa Inoue, Yayoi Hayashi, Hiroaki Yuasa. EFFECT OF MYRICETIN ON RIBOFLAVIN TRANSPORTER 3. DRUG METABOLISM REVIEWS. 2015. 47. 281-281

Education (3)：

2015 - 2018 Nagoya City University Graduate School of Pharmaceutical Sciences
2013 - 2015 Nagoya City University Graduate School of Pharmaceutical Sciences
2009 - 2013 Nagoya City University Medicin Department of Pharmatical and Life Science

Professional career (1)：

Work history (2)：

2018/04 - 現在 Nagoya City University Graduate School of Pharmaceutical Sciences
2022/11 - 2023/10 University of California, Irvine School of Medicine visiting scholar

Awards (3)：

2023/03 - 日本薬学会長井記念若手薬学研究者賞
2017/12 - APSTJ Global Education Seminar 2017-3rd Global Education Seminar Presentation Award 2017
2017/09 - 21st North American ISSX Meeting Best Presentation Award Third Place

Association Membership(s) (3)：

THE PHARMACEUTICAL SOCIETY OF JAPAN , THE ACADEMY OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, JAPAN , THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS

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