Rchr
J-GLOBAL ID：201801020555239016   Update date: Apr. 25, 2024

Kinoshita Rie

キノシタ リエ | Kinoshita Rie
Affiliation and department：
Okayama University Science of Functional Recovery and Reconstruction,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

About Okayama University Science of Functional Recovery and Reconstruction,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences


Job title： Assistant Professor
Homepage URL  (2)： https://www.okayama-u.ac.jp/user/cellbiol/ ,  https://pxy-www.a.okayama-u.ac.jp/user/cellbiol/
Research field  (1)： Cell biology
Research keywords  (3)： 抗体医薬品 ,  細胞生物学 ,  Cell biology
Research theme for competitive and other funds  (10)：
  • 2023 - 2027 原発巣の腫瘍縮小および転移抑制効果を示す膵がん治療薬の開発
  • 2023 - 2026 S100A8/A9-向転移とHRG-抗転移の細胞間・分子間クロストークの解明
  • 2022 - 2025 乾癬、アトピー性皮膚炎におけるMCAMの意義探求とその制御製剤による病態制御
  • 2020 - 2023 β3インテグリン遺伝子導入ヒト表皮角化細胞を用いた難治性潰瘍に対する新規再生医療
  • 2020 - 2023 S100A8/A9が悪性化する原発巣および転移先がん微小環境を制御する治療法
Show all
Papers (43)：
  • Tetta Takahashi, Nahoko Tomonobu, Rie Kinoshita, Ken-ichi Yamamoto, Hitoshi Murata, Ni Luh Gede Yoni Komalasari, Youyi Chen, Fan Jiang, Yuma Gohara, Toshiki Ochi, et al. Lysyl oxidase-like 4 promotes the invasiveness of triple-negative breast cancer cells by orchestrating the invasive machinery formed by annexin A2 and S100A11 on the cell surface. Frontiers in Oncology. 2024. 14
  • Hitoshi Murata, May Tha Zin Phoo, Toshiki Ochi, Nahoko Tomonobu, Ken-Ichi Yamamoto, Rie Kinoshita, Ikuko Miyazaki, Masahiro Nishibori, Masato Asanuma, Masakiyo Sakaguchi. Phosphorylated SARM1 is involved in the pathological process of rotenone-induced neurodegeneration. Journal of biochemistry. 2023
  • 久保 美代子, 山本 健一, 木下 理恵, 米澤 朋子, 大橋 俊孝, 阪口 政清. β3インテグリン遺伝子導入ヒト表皮角化細胞を用いた難治性潰瘍に対する新規再生医療の開発. 日本結合組織学会学術大会プログラム・抄録集. 2023. 55回. 134-134
  • Hitoshi Murata, Yu Yasui, Kazuma Oiso, Toshiki Ochi, Nahoko Tomonobu, Ken-Ichi Yamamoto, Rie Kinoshita, Masakiyo Sakaguchi. STAT1/3 signaling suppresses axon degeneration and neuronal cell death through regulation of NAD+-biosynthetic and consuming enzymes. Cellular signalling. 2023. 108. 110717-110717
  • Yuma Gohara, Nahoko Tomonobu, Rie Kinoshita, Junichiro Futami, Léna Audebert, Youyi Chen, Ni Luh Gede Yoni Komalasari, Fan Jiang, Chikako Yoshizawa, Hitoshi Murata, et al. Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells. Journal of molecular medicine (Berlin, Germany). 2023. 101. 4. 431-447
ｍore...
MISC (45)：
  • 村田等, 安藤隆幸, 安井優, 越智俊樹, 友信奈保子, 山本健一, 木下理恵, 阪口政清. Development of inhibitors of axonal degeneration-inducing molecule SARM1 using human iPS cell-derived neurons and animal models. 組織培養研究(Web). 2023. 41. 2
  • D. Shimizu, M. Okazaki, S. Sugimoto, R. Kinoshita, S. Kawana, Y. Kubo, K. Matsubara, K. Nakata, A. Matsukawa, M. Sakaguchi, et al. Inhibiting S100A8/A9 Attenuates Airway Obstruction in a Mouse Heterotopic Tracheal Transplantation Model. The Journal of Heart and Lung Transplantation. 2022. 41. 4
  • 村田等, 安藤隆幸, 大磯和真, 友信奈保子, 山本健一, 木下理恵, 阪口政清. 軸索変性誘導分子SARM1の阻害剤開発. 日本神経化学会大会抄録集(Web). 2022. 65th
  • Akira Yamauchi, Masahiro Yamamura, Naoki Katase, Nahoko Tomonobu, Rie Kinoshita, Masakiyo Sakaguchi, Shuichiro Okamoto. NOX4 on lymphatic endothelial cells (LEC) plays an important role on the migration of pancreatic cancer cells. CANCER SCIENCE. 2021. 112. 347-347
  • 山内明, 山村真弘, 片瀬直樹, 友信奈保子, 木下理恵, 阪口政清, 岡本秀一郎. NOX4 on lymphatic endothelial cells (LEC) plays an important role on the migration of pancreatic cancer cells. 日本癌学会学術総会抄録集(Web). 2020. 79th
ｍore...
Patents (16)：
  • リン酸化SARM1、抗体、SARM1リン酸化阻害剤、神経変性患者の予防または治療薬、スクリーニング方法、SARM1改変体及び使用
  • 炎症性肺疾患の予防及び/又は治療剤
  • 炎症性肺疾患の予防及び/又は治療剤
  • 炎症性肺疾患の予防及び/又は治療剤
  • 炎症性肺疾患の予防及び/又は治療剤
ｍore...
Lectures and oral presentations  (32)：
  • Development of pancreatic cancer therapy targeting S100A8/A9 of tumor microenvironment
    (2023)
  • S100A8/A9 とその新制御分子のバランスで成立するがん転移の機序解明
    (日本組織培養学会第95回大会 2023)
  • 膵がん進展におけるS100A8/A9 の機能解析と抗体による治療への応用
    (日本組織培養学会第95回大会 2023)
  • Development of therapeutic antibodies based on the elevated S100A8/A9 in tumor microenvironment
    (2022)
  • The role of macrophages in anti-S100A8/A9 therapy for inflammatory diseases
    (2022)
ｍore...
Education (4)：
  • - 2015 Okayama University
  • - 2015 Okayama University Graduate School, Division of Engineering
  • - 2000 Okayama University Faculty of Engineering Department of Bioscience and Biotechnology
  • - 2000 Okayama University Faculty of Engineering
Professional career (1)：
  • 博士(工学) (岡山大学)
Work history (2)：
  • 2015 - - 岡山大学医歯薬学総合研究科機能再生・再建科学専攻 助教
  • 2015 - - Assistant Professor,Science of Functional Recovery and Reconstruction,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
Association Membership(s) (2)：
The Japanese Cancer Association ,  The Japanese Tissue Culture Association
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page

TOP

BOTTOM