Rchr
J-GLOBAL ID：201801020555239016   Update date: Nov. 05, 2024

Kinoshita Rie

キノシタ リエ | Kinoshita Rie
Affiliation and department：
Okayama University Science of Functional Recovery and Reconstruction,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

About Okayama University Science of Functional Recovery and Reconstruction,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences


Job title： Assistant Professor
Homepage URL  (2)： https://www.okayama-u.ac.jp/user/cellbiol/ ,  https://pxy-www.a.okayama-u.ac.jp/user/cellbiol/
Research field  (1)： Cell biology
Research keywords  (3)： 抗体医薬品 ,  細胞生物学 ,  Cell biology
Research theme for competitive and other funds  (11)：
  • 2023 - 2027 原発巣の腫瘍縮小および転移抑制効果を示す膵がん治療薬の開発
  • 2023 - 2026 S100A8/A9-向転移とHRG-抗転移の細胞間・分子間クロストークの解明
  • 2023 - 2026 S100A8/A9-向転移とHRG-抗転移の細胞間・分子間クロストークの解明
  • 2022 - 2025 乾癬、アトピー性皮膚炎におけるMCAMの意義探求とその制御製剤による病態制御
  • 2020 - 2023 β3インテグリン遺伝子導入ヒト表皮角化細胞を用いた難治性潰瘍に対する新規再生医療
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Papers (39)：
  • Yohei Takahashi, Soe Soe Htwe, Dengli Wang, Hidenori Wake, Mariko Yata, Nahoko Tomonobu, Rie Kinoshita, Masakiyo Sakaguchi, Masahiro Nishibori. Antithrombin regulates neutrophil activities through the stimulation of C-type lectin family 1A. Blood Vessels, Thrombosis & Hemostasis. 2024
  • Jin Zhou, Hitoshi Murata, Nahoko Tomonobu, Naoko Mizuta, Atsuko Yamakawa, Ken-Ichi Yamamoto, Rie Kinoshita, Masakiyo Sakaguchi. S100A11 is involved in the progression of colorectal cancer through the desmosome-catenin-TCF signaling pathway. In vitro cellular & developmental biology. Animal. 2024
  • Fan Jiang, Youyi Chen, Nahoko Tomonobu, Rie Kinoshita, Ni Luh Gede, Yoni Komalasari, Carlos Ichiro, Kasano-Camones, Kazumi Ninomiya, Hitoshi Murata, et al. Dissection of the signal transduction machinery responsible for the lysyl oxidase-like 4-mediated increase in invasive motility in triple-negative breast cancer cells: mechanistic insight into the integrin-β1-NF-κB-MMP9 axis. Front. Oncol. Sec. Molecular and Cellular Oncology. 2024. 14. 1371307
  • Tetta Takahashi, Nahoko Tomonobu, Rie Kinoshita, Ken-ichi Yamamoto, Hitoshi Murata, Ni Luh Gede Yoni Komalasari, Youyi Chen, Fan Jiang, Yuma Gohara, Toshiki Ochi, et al. Lysyl oxidase-like 4 promotes the invasiveness of triple-negative breast cancer cells by orchestrating the invasive machinery formed by annexin A2 and S100A11 on the cell surface. Frontiers in Oncology. 2024. 14
  • Hitoshi Murata, May Tha Zin Phoo, Toshiki Ochi, Nahoko Tomonobu, Ken-Ichi Yamamoto, Rie Kinoshita, Ikuko Miyazaki, Masahiro Nishibori, Masato Asanuma, Masakiyo Sakaguchi. Phosphorylated SARM1 is involved in the pathological process of rotenone-induced neurodegeneration. Journal of biochemistry. 2023
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MISC (58)：
  • 久保 美代子, 山本 健一, 木下 理恵, 米澤 朋子, 大橋 俊孝, 阪口 政清. β3インテグリン遺伝子導入ヒト表皮角化細胞を用いた難治性潰瘍に対する新規再生医療の開発. 日本結合組織学会学術大会プログラム・抄録集. 2023. 55回. 134-134
  • 合原勇馬, 友信奈保子, 木下理恵, 山本建一, 村田等, 阪口政清. Nuclear PD-L1 facilitates disseminative activity by suppressing Protein X in triple-negative breast cancer cells. 日本癌学会学術総会抄録集(Web). 2023. 82nd
  • 友信奈保子, 木下理恵, 合原勇馬, KOMALASARI Yoni, 二見淳一郎, 山内明, 近藤英作, 豊岡伸一, 阪口政清. S100A8/A9 promotes bladder cancer progression by the TIRAP-TPL2 signaling upon the binding with TLR4. 日本癌学会学術総会抄録集(Web). 2023. 82nd
  • 合原勇馬, 友信奈保子, 木下理恵, 村田等, 山本健一, 難波正義, 許南浩, 公文裕己, 阪口政清. A novel function of REIC protein on tumor suppression through the downregulation of PD-L1 on cancer cells. 組織培養研究(Web). 2023. 41. 2
  • 山本健一, 平林大輔, 丸山顕嘉, 友信奈保子, 木下理恵, KOMALASARI Ni Luh Gade Yoni, 村田等, 合原勇馬, 江帆, 山内明, et al. The Zn2+-bound form of ZEB1 plays a crucial part in the promotion of invasiveness in breast cancer cells. 組織培養研究(Web). 2023. 41. 2
ｍore...
Patents (16)：
  • リン酸化SARM1、抗体、SARM1リン酸化阻害剤、神経変性患者の予防または治療薬、スクリーニング方法、SARM1改変体及び使用
  • 炎症性肺疾患の予防及び/又は治療剤
  • 炎症性肺疾患の予防及び/又は治療剤
  • 炎症性肺疾患の予防及び/又は治療剤
  • 炎症性肺疾患の予防及び/又は治療剤
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Lectures and oral presentations  (32)：
  • Development of pancreatic cancer therapy targeting S100A8/A9 of tumor microenvironment
    (2023)
  • S100A8/A9 とその新制御分子のバランスで成立するがん転移の機序解明
    (日本組織培養学会第95回大会 2023)
  • 膵がん進展におけるS100A8/A9 の機能解析と抗体による治療への応用
    (日本組織培養学会第95回大会 2023)
  • Development of therapeutic antibodies based on the elevated S100A8/A9 in tumor microenvironment
    (2022)
  • The role of macrophages in anti-S100A8/A9 therapy for inflammatory diseases
    (2022)
ｍore...
Education (4)：
  • - 2015 Okayama University
  • - 2015 Okayama University Graduate School, Division of Engineering
  • - 2000 Okayama University Faculty of Engineering Department of Bioscience and Biotechnology
  • - 2000 Okayama University Faculty of Engineering
Professional career (1)：
  • 博士(工学) (岡山大学)
Work history (2)：
  • 2015 - - 岡山大学医歯薬学総合研究科機能再生・再建科学専攻 助教
  • 2015 - - Assistant Professor,Science of Functional Recovery and Reconstruction,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
Association Membership(s) (2)：
The Japanese Cancer Association ,  The Japanese Tissue Culture Association
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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