Research theme for competitive and other funds (2):
2020 - 2025 Science of fairy chemicals and their application development
2017 - 2021 多彩な天然物合成と反応開発が加速させる創薬研究
Papers (27):
Makoto Inai, Hiroto Sagara, Yoshinori Ueno, Hitoshi Ouchi, Fumihiko Yoshimura, Tomohiro Asakawa, Yoshitaka Hamashima, Toshiyuki Kan. Total Synthesis of (+)-Silybin A. Chemical & pharmaceutical bulletin. 2024. 72. 6. 570-573
Hirohide Takemura, Jae-Hoon Choi, Keiji Fushimi, Rei Narikawa, Jing Wu, Mitsuru Kondo, David C Nelson, Tomohiro Suzuki, Hitoshi Ouchi, Makoto Inai, et al. Role of hypoxanthine-guanine phosphoribosyltransferase in the metabolism of fairy chemicals in rice. Organic & biomolecular chemistry. 2023. 21. 12. 2556-2561
Mihaya Kotajima, Jae-Hoon Choi, Hyogo Suzuki, Tomohiro Suzuki, Jing Wu, Hirofumi Hirai, David C Nelson, Hitoshi Ouchi, Makoto Inai, Hideo Dohra, et al. Identification of Biosynthetic and Metabolic Genes of 2-Azahypoxanthine in Lepista sordida Based on Transcriptomic Analysis. Journal of natural products. 2023. 86. 4. 710-718
Mihaya Kotajima, Jae-Hoon Choi, Tomohiro Suzuki, Jing Wu, Hirofumi Hirai, David C Nelson, Hitoshi Ouchi, Makoto Inai, Hideo Dohra, Hirokazu Kawagishi. The role of xanthine dioxygenase in the biosynthetic pathway of 2-aza-8-oxohypoxanthine of Lepista sordida. Bioscience, Biotechnology, and Biochemistry. 2023. 87. 4. 420-425
Shigeru Nishizawa, Hitoshi Ouchi, Hiroto Suzuki, Takuma Ohnishi, Shingo Sasaki, Yu Oyagi, Masaki Kanakogi, Yoshitaka Matsumura, Shunsuke Nakagawa, Tomohiro Asakawa, et al. Total synthesis of (-)-domoic acid, a potent ionotropic glutamate receptor agonist and the key compound in oceanic harmful algal blooms. Organic & Biomolecular Chemistry. 2023. 21. 8. 1653-1656
入江樂, 高木紗羅, 若林稜也, 谷知恵, 松永智子, 稲井誠, 大内仁志, 酒井隆一, 菅敏幸, 及川雅人. Structure elucidation of protoaculeine B and aculeines by solid-phase total synthesis. 日本化学会春季年会講演予稿集(Web). 2023. 103rd
高木紗羅, 入江樂, 若林稜也, 入江由美, 辺浩美, 谷知恵, 松永智子, 稲井誠, 大内仁志, 菅敏幸, et al. Concise synthesis of artificial aculeine analogs based on click chemistry and evaluation of their bioactivities. 日本化学会春季年会講演予稿集(Web). 2023. 103rd
福田拓実, 藤井りょう, 鹿子木匡貴, 森兼悠太, 大内仁志, 吉村文彦, 滝田良, 稲井誠, 菅敏幸. Synthetic study of Lobatamide A. 日本薬学会年会要旨集(Web). 2023. 143rd
内田雅哉, 新田目かおり, 大内仁志, 稲井誠, 吉村文彦, 滝田良, 菅敏幸. Total Synthesis of (±)-Halichonine B. 日本薬学会年会要旨集(Web). 2023. 143rd