Rchr
J-GLOBAL ID：201801020747562430   Update date: Nov. 18, 2024

Ueda Yasutaka

ウエダ ヤスタカ | Ueda Yasutaka
Affiliation and department：
Osaka University Graduate School of Medicine Division of Medicine

About Osaka University Graduate School of Medicine Division of Medicine


Job title： Assistant Professor
Research field  (1)： Hematology and oncology
Research keywords  (4)： Complement Diseases ,  Paroxysmal Nocturnal Hemoglobinuria ,  Bone Marrow Failure Syndromes ,  Hematology
Research theme for competitive and other funds  (7)：
  • 2023 - 2026 Unraveling the mechanism of poor response to anti-comlement drug in cold agglutinin disease treatment
  • 2022 - 2025 PNHクローンの起源と変遷
  • 2019 - 2022 Identification of the most appropriate therapeutic target for PNH
  • 2019 - 2020 Analysis for hematopoietic dynamics of clonal expansion in PNH
  • 2017 - 2020 Elucidation of mechanism of pathogenesis of paroxysmal nocturnal hemoglobinuria
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Papers (44)：
  • Raymond Wong, Jun Ho Jang, Lily Lee Lee Wong, JIN SEOK KIM, Ponlapat Rojnuckarin, Yeow Tee Goh, Yasutaka Ueda, Wen-Chien Chou, Jong Wook Lee, Yuzuru Kanakura, et al. Monitoring and Treatment of Paroxysmal Nocturnal Hemoglobinuria in Patients with Aplastic Anemia in Asia: An Expert Consensus. International Journal of Molecular Sciences. 2024
  • Zenjiro Sampei, Kenta Haraya, Siok Wan Gan, Masaru Muraoka, Akira Hayasaka, Taku Fukuzawa, Meiri Shida-Kawazoe, Yoshinori Tsuboi, Akihiko Gotoh, Naoshi Obara, et al. Beyond Recycling Antibodies: Crovalimab’s Molecular Design Enables Four-Weekly Subcutaneous Injections for PNH Treatment. International Journal of Molecular Sciences. 2024
  • Phillip Scheinberg, Diego Villa Clé, Jin Seok Kim, Erfan Nur, Mustafa N Yenerel, Wilma Barcellini, Debora Bonito, Valentina Giai, Marek Hus, YooJin Lee, et al. Phase 3 randomized COMMODORE 1 trial: Crovalimab versus eculizumab in complement inhibitor-experienced patients with paroxysmal nocturnal hemoglobinuria. American journal of hematology. 2024. 99. 9. 1757-1767
  • Régis Peffault de Latour, Alexander Röth, Austin G Kulasekararaj, Bing Han, Phillip Scheinberg, Jaroslaw P Maciejewski, Yasutaka Ueda, Carlos M de Castro, Eros Di Bona, Rong Fu, et al. Oral Iptacopan Monotherapy in Paroxysmal Nocturnal Hemoglobinuria. The New England journal of medicine. 2024. 390. 11. 994-1008
  • Ken Ishiyama, Yuji Yonemura, Tatsuya Kawaguchi, Kohei Hosokawa, Chiharu Sugimori, Yasutaka Ueda, Hiroyuki Takamori, Naoshi Obara, Hideyoshi Noji, Yukari Shirasugi, et al. A longitudinal analysis of paroxysmal nocturnal haemoglobinuria-type cells in patients with bone marrow failure: Results of a prospective multi-centre study in Japan. British journal of haematology. 2023
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MISC (67)：
  • 植田 康敬. 様々な疾患が合併する血栓症の病態解明と治療フロンティア 補体介在性溶血性貧血と血栓症. 日本血栓止血学会誌. 2024. 35. 2. 139-139
  • 植田 康敬. PNHの診断と治療,合併症の管理. 日本血栓止血学会誌. 2024. 35. 2. 208-208
  • 植田 康敬, Roth Alexander, McCrae Keith, Khan Umer, Kralova Katarina, Wardecki Marek, Shafer Frank, Yoo Ronnie, Broome Catherine. 寒冷凝集素症における血栓塞栓症イベント CARDINAL/CADENZA試験の事後解析. 日本血栓止血学会誌. 2024. 35. 2. 308-308
  • 植田 康敬. 【患者さんからよく尋ねられる内科診療のQuestion】(第4章)血液 [70歳代男性,発作性夜間ヘモグロビン尿症]発作性夜間ヘモグロビン尿症で抗補体薬の治療を受けています.自宅で熱が出たら,とりあえずは解熱薬で様子をみてよいでしょうか?. 内科. 2024. 133. 4. 740-743
  • 植田 康敬. 【造血不全症の診療】寒冷凝集素症に対する補体標的治療. 血液内科. 2024. 88. 3. 259-263
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Books (3)：
  • EBM血液疾患の治療2023-2024
    中外医学社 2022 ISBN:9784498225404
  • 臨床薬理の進歩
    臨床薬理研究振興財団 2020
  • 血液専門医テキスト
    南江堂 2019 ISBN:9784524248827
Lectures and oral presentations  (11)：
  • Trial in Progress: Randomized, Double-Blind, Placebo-Controlled Multicenter Phase 3 Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients with Cold Agglutinin Disease (CASCADE)
    (64th American Soceity of Hematology Annual Meeting and Expostion)
  • Importance of controling intravascular hemolysis in PNH -what we learned in the past 10 years-
    (2022)
  • Advances in understanding of pathogenesis and treatment of autoimmune hemolytic anemia.
    (2022)
  • Cold agglutini disease and comlement inhibitors
    (2022)
  • Safety and Efficacy of SARS-CoV-2 mRNA Vaccination in Paroxysmal Nocturnal Hemoglobinuria Patients:An Institutional Experience
    (2022)
ｍore...
Education (2)：
  • 2002 - 2008 Osaka University Graduate School of Medicine
  • 1993 - 1999 Osaka University Faculty of Medicine Medical School
Work history (1)：
  • 2011/07 - 2014/06 National Heart, Lung, and Blood Institute, National Institutes of Health VIsiting Fellow
Committee career (2)：
  • 2022/11 - 現在 The Japanese Society of Hematology Program planning committee member
  • 2021/09 - 現在 日本血液学会 試験問題作成委員
Awards (3)：
  • 2021/03 - Intractable disease research grant
  • 2020/12 - 大阪大学大学院医学系研究科・医学部附属病院産学連携・クロスイノベーションイニシア ティブ 令和2 年度新型コロナウイルス対策研究開発助成事業 COVID-19血栓性微小血管障害における補体活性化の意義の解明
  • 2011/06 - 住友生命社会福祉事業団 海外医学研究助成
Association Membership(s) (5)：
THE JAPANESE BIOCHEMICAL SOCIETY ,  The Japan Society for Hematopoietic Cell Transplantation ,  American Society of Hematology ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE ,  THE JAPANESE SOCIETY OF HEMATOLOGY
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