Kataoka Makoto

カタオカマコト | Kataoka Makoto

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.setsunan.ac.jp/~p-pharm/

Research field (3)： Pharmaceuticals - health and biochemistry , Clinical pharmacy , Pharmaceuticals - chemistry and drug development

Research keywords (10)：薬物間相互作用 , 輸送担体 , 薬物代謝 , 過飽和 , 製剤 , 吸収改善 , 難水溶性 , Solubility , Permeability , Oral absorption

Research theme for competitive and other funds (10)：

2023 - 2026 アンテドラッグとして作用する、安全で新規な薬物動態学的増強因子の創出
2023 - 2026 難溶性薬物共結晶からのin vitro薬物経口吸収評価法と新規共結晶溶解制御法の構築
2021 - 2022 加齢や相互作用による消化管内生理条件変化に起因した薬物体内動態変化の抑制を指向した新規経口吸収改善製剤コンセプトの確立
2020 - 2021 小腸内薬物代謝酵素を選択的に阻害する新規boosterの創製
2018 - 2021 Effect of dietary intake of medium chain triglycerides on intestinal absorption of poorly-permeable compounds

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Papers (105)：

Kentaro Kawai, Yukiko Karuo, Atsushi Tarui, Kazuyuki Sato, Makoto Kataoka, Masaaki Omote. Development of Drug Discovery Platforms Using Artificial Intelligence and Cheminformatics. Chemical and Pharmaceutical Bulletin. 2024. 72. 9. 794-799
Makoto Kataoka, Sae Takenaka, Shota Fujii, Takato Masada, Keiko Minami, Toshihide Takagi, Masaaki Omote, Kentaro Kawai, Shinji Yamashita. In vitro demonstration of antedrug mechanism of a pharmacokinetic booster to improve CYP3A4 substrates by CYP3A4-mediated metabolism inhibition. Drug Metabolism and Pharmacokinetics. 2024
Makoto Kataoka, Yoshiya Itaka, Takato Masada, Keiko Minami, Haruki Higashino, Shinji Yamashita. Near-infrared imaging of in vivo performance of orally administered solid forms to rats: Feasibility study with indocyanine green. International Journal of Pharmaceutics. 2024. 649. 123677-123677
Toshihide Takagi, Takato Masada, Keiko Minami, Makoto Kataoka, Shinji Yamashita. Development of an In Vitro Methodology to Assess the Bioequivalence of Orally Disintegrating Tablets Taken without Water. Pharmaceutics. 2023. 15. 9. 2192-2192
Makoto Kataoka, Ayaka Yonehara, Keiko Minami, Toshihide Takagi, Shinji Yamashita. Control of Dissolution and Supersaturation/Precipitation of Poorly Water-Soluble Drugs from Cocrystals Based on Solubility Products: A Case Study with a Ketoconazole Cocrystal. Molecular pharmaceutics. 2023. 20. 8. 4100-4107

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MISC (22)：

植田圭祐, 東顕二郎, 片岡誠, 山下伸二, 山本恵司, 森部久仁一. 消化管モデル溶液中におけるHPMC-ASの薬物結晶化抑制. 日本薬剤学会年会講演要旨集(Web). 2015. 30th. 96-96
植田圭祐, 東顕二郎, 片岡誠, 山下伸二, 山本恵司, 森部久仁一. HPMC-ASの薬物結晶化抑制作用に及ぼす胆汁酸及び脂質の影響. 日本薬学会年会要旨集(CD-ROM). 2015. 135th. 4. 79-79
片岡誠. 経口製剤開発のためのヒト経口吸収性評価システム. Drug Metabolism and Pharmacokinetics. 2013
KATAOKA Makoto. In Vitro System to Evaluate Oral Absorption of Poorly Water-Soluble Drugs : Simultaneous Analysis on Dissolution and Permeation of Drugs. 2012. 72. 6. 344-348
Wellington Pham, Hironori Kumagai, Ken-Ichiro Hiwatari, Hiroyuki Tachikawa, Ryoji Kimura, Kunio Nakamura, Makoto Kataoka, Shinji Yamashita, Shinji Sakuma. Preclinical validation of the sensitivity and specificity of a fluorescent nanobeacon for its application in colonoscopy-based imaging of colorectal cancer. CANCER RESEARCH. 2011. 71

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Books (5)：

Lectures and oral presentations (386)：

Development of a novel safe booster with antedrug characteristics to improve oral bioavailability of CYP3A Substrates
(2023 International Joint Meeting of the 23rd International Conference on Cytochrome P450 and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics)
電荷反転型脂質誘導体を用いたペプチド封入LNPの調製~ペプチドの経口デリバリーを目指した検討~
(日本薬剤学会第38年会)
ケトコナゾール共結晶の最適化とキャラクタリゼーション
(日本薬剤学会第38年会)
機能性ゼリー剤の開発(2)用時調製型低pHゼリー剤
(日本薬剤学会第38年会)
機能性ゼリー剤の開発(1)過飽和型製剤としての低pHゼリー剤
(日本薬剤学会第38年会)

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Education (4)：

Professional career (1)：

Work history (6)：

2023/04 - 現在摂南大学薬学部薬剤学研究室教授
2017/04 - 2023/03 摂南大学薬学部薬剤学研究室准教授
2019/09 - 2020/08 University of Michigan College of Pharmacy, Department of Pharmaceutical Sciences Visiting Scientist
2014/04 - 2017/03 摂南大学薬学部薬剤学研究室講師
2007/04 - 2014/03 摂南大学薬学部薬剤学研究室助教

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Committee career (13)：

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Awards (5)：

Association Membership(s) (3)：

日本薬学会 , 日本薬物動態学会 , 日本薬剤学会

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