Aya Ushio

ウシオアヤ | Aya Ushio

Affiliation and department：

Research field (2)： Immunology , Experimental pathology

Research keywords (6)：性差 , 口腔病理学 , マクロファージ , 唾液腺 , 自己免疫疾患 , シェーグレン症候群

Research theme for competitive and other funds (9)：

2023 - 2027 Novel pathogenesis and therapeutic strategy of autoimmunity based on immune-tuning molecules
2024 - 2026 共食い口腔がん細胞による新たな腫瘍免疫逃避機構の同定
2024 - 2026 新生仔期胸腺におけるT細胞分化が自己免疫疾患の発症に与える影響
2023 - 2025 Clinical application based on the molecular mechanism of autoantibody production in autoimmunity
2021 - 2024 性ホルモンと自然免疫を介したシェーグレン症候群の新たな病因論の構築

Show all

Papers (19)：

Aya Ushio, Mami Matsuda-Lennikov, Felix Kalle-Youngoue, Akihide Shimizu, Abdalla Abdelmaksoud, Michael C Kelly, Naozumi Ishimaru, Yousuke Takahama. Functionally diverse thymic medullary epithelial cells interplay to direct central tolerance. Cell reports. 2024. 43. 4. 114072-114072
Hiroaki Tawara, Takaaki Tsunematsu, Shojiro Kitajima, Ruka Nagao, Shigefumi Matsuzawa, Kunihiro Otsuka, Aya Ushio, Naozumi Ishimaru. The noncanonical function of borealin, a component of chromosome passenger complex, promotes glycolysis via stabilization of survivin in squamous cell carcinoma cells. Biochemical and biophysical research communications. 2024. 706. 149741-149741
Mami Sato-Fukuba, Rieko Arakaki, Aya Ushio, Kunihiro Otsuka, Ruka Nagao, Shigefumi Matsuzawa, Hiroaki Tawara, Takaaki Tsunematsu, Naozumi Ishimaru. CD4+ T-cell-dependent differentiation of CD23+ follicular B cells contributes to the pulmonary pathology in a primary Sjögren’s syndrome mouse model. Frontiers in Immunology. 2023. 14
Mami Sato, Rieko Arakaki, Hiroaki Tawara, Ruka Nagao, Hidetaka Tanaka, Kai Tamura, Yuhki Kawahito, Kunihiro Otsuka, Aya Ushio, Takaaki Tsunematsu, et al. Disturbed natural killer cell homeostasis in the salivary gland enhances autoimmune pathology via IFN-γ in a mouse model of primary Sjögren's syndrome. Frontiers in medicine. 2022. 9. 1036787-1036787
大塚邦紘, 常松貴明, 牛尾綾, 石丸直澄. カラー図説:シェーグレン症候群の病理. 日本臨床. 2022. 80. 1538-1543

ｍore...

MISC (84)：

俵宏彰, 常松貴明, 永尾瑠佳, 福田一稀, 佐藤真美, 大塚邦紘, 牛尾綾, 石丸直澄. 頭頸部扁平上皮癌における染色体パッセンジャー複合体構成因子Borealinの高発現がもたらす新たな役割. 口腔組織培養学会誌. 2023. 32. 1
牛尾綾, LENNIKOV Mami, 大塚邦紘, 常松貴明, 石丸直澄, 高濱洋介. The layer protection of heterogeneous medullary thymic epithelial cells for autoimmune disease. 日本病理学会会誌. 2023. 112. 1
大塚邦紘, 大塚邦紘, 大塚邦紘, 近藤博之, 九十九伸一, 九十九伸一, 新垣理恵子, 永尾瑠佳, 佐藤真美, 牛尾綾, et al. CD153-CD30 axis contributes to the autoimmune pathology in salivary glands of Sjogren’s syndrome. 日本病理学会会誌. 2023. 112. 1
永尾瑠佳, 大塚邦紘, 山本安希子, 牛尾綾, 佐藤真美, 俵宏彰, 田中秀卓, 常松貴明, 石丸直澄. Analysis of the role of co-inhibitory receptors on T cells to the pathogenesis of Sjogren’s syndrome. 日本病理学会会誌. 2023. 112. 1
常松貴明, 俵宏彰, 佐藤真美, 永尾瑠佳, 福田一稀, 大塚邦紘, 牛尾綾, 石丸直澄. The acquired novel role of cancer cells induced by DNA damage signaling and its molecular mechanism. 日本病理学会会誌. 2023. 112. 1

ｍore...

Lectures and oral presentations (3)：

Do heterogeneous thymic medullary epithelial subpopulations cooperate to provide self-tolerance in T cells?
(Experimental Immunology Branch Seminar 2022)
mTEC heterogeneity and autoimmune disease.
(Experimental Immunology Branch Seminar 2021)
CCL22-producing resident macrophages enhances inflammation in salivary glands of Sjögren’s syndrome.
(11th International Congress on Autoimmunity)

Education (1)：

Work history (8)：

2024/07 - 現在 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences
2024/01 - 2024/06 The University of Tokushima
2022/09 - 2023/12 The University of Tokushima
2020/04 - 2022/08 National Institutes of Health National Cancer Institute Posto-doctoral fellow
2019/04 - 2019/12 徳島大学病院診療支援歯科医師

Show all

Committee career (1)：

Awards (8)：

2024/08 - 一般財団法人岩垂育英会令和6年度岩垂育英会賞
2019/12 - 徳島大学歯学部第25回高田充歯科基礎医学奨励賞
2019/09 - 日本シェーグレン症候群学会第13回日本シェーグレン症候群学会奨励賞 CCL22-producing Resident Macrophage Enhance T Cell Response in Sjögren's syndrome.
2019/07 - 徳島大学歯学部徳島大学歯学部長表彰
2017/08 - 先端歯学国際教育研究ネットワーク先端歯学スクール2017優秀賞シェーグレン症候群の唾液腺におけるマクロファージサブセットと病態への関与

Show all

Association Membership(s) (4)：

日本免疫学会 , 日本シェーグレン症候群学会 , 日本病理学会 , 日本歯科基礎医学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page