Atsushi Tanaka

タナカアツシ | Atsushi Tanaka

Affiliation and department：

Research field (2)： Tumor diagnostics and therapeutics , Immunology

Research keywords (6)：免疫自己寛容 , がん免疫 , TCRシグナル分子 , がん免疫療法 , 制御性T細胞 (Treg) , 自己免疫病

Research theme for competitive and other funds (7)：

2022 - 2027 Targeting Treg cells in cancer immunotherapy
2023 - 2025 次世代がん医療加速化研究事業(P-PROMOTE)
2022 - 2023 医療研究開発革新基盤創成事業
2017 - 2019 Molecular basis of Treg-specific TCR signaling regulation
2015 - 2018 Identification of Genes Controlling Treg Development by Combining the CRISPR-Cas9 System and Bone Marrow Chimeric Mouse Model

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Papers (26)：

Christopher Tay, Atsushi Tanaka, Shimon Sakaguchi. Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy. Cancer Cell. 2023. 41. 3. 450-465
Atsushi Tanaka, Shinji Maeda, Takashi Nomura, Mara Anais Llamas-Covarrubias, Satoshi Tanaka, Lin Jin, Ee Lyn Lim, Hiromasa Morikawa, Yohko Kitagawa, Shuji Akizuki, et al. Construction of a T cell receptor signaling range for spontaneous development of autoimmune disease. Journal of Experimental Medicine. 2023. 220. 2
Kazunori Yokoi, Rei Watanabe, Miki Kume, Saki Yamane, Atsushi Tanaka, Manabu Fujimoto, Atsushi Tanemura. Melanocyte-specific CD49a ⁺ CD8 ⁺ T cells in vitiligo lesion potentiate to maintain activity during systemic steroid therapy. The Journal of Dermatology. 2022
Takuya Sato, Youichi Ogawa, Kazunori Yokoi, Yuka Nagasaka, Aoha Ishikawa, Ichiro Shiokawa, Manao Kinoshita, Rei Watanabe, Shinji Shimada, Atsushi Tanaka, et al. Characterization of human epithelial resident memory regulatory T cells. Frontiers in Immunology. 2022. 13. 962167-962167
Dean Thumkeo, Siwakorn Punyawatthananukool, Somsak Prasongtanakij, Ryuma Matsuura, Kentaro Arima, Huan Nie, Rie Yamamoto, Naohiro Aoyama, Hisao Hamaguchi, Shingo Sugahara, et al. PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment. Cell Reports. 2022. 39. 10. 110914-110914

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MISC (12)：

河嶋厚成, 冨山栄輔, 洪陽子, 松下慎, 中野剛佑, 林裕次郎, 加藤大悟, 波多野浩士, 氏家剛, 植村元秀, et al. ニボルマブ抵抗性高悪性度腎細胞癌で高発現する制御性T細胞に特異的な分子CCR8を標的とした新規免疫療法の開発. 日本癌学会総会記事. 2020. 79回. OE14-1
田中淳. エフェクターTregとがん免疫. 臨床免疫・アレルギー科. 2020. 74. 1. 74-79
藤岡優樹, 高橋直人, 田中淳. イマチニブによるエフェクター制御性T細胞の除去と抗腫瘍免疫の活性化. 血液内科. 2020. 81. 554-561
木林達也, 田中淳. ヒトFoxP3+制御性T細胞の多様性とその解析. 臨床免疫・アレルギー科. 2020. 74. 307-313
田中淳, 坂口志文. Treg特異的なTCRシグナルの分子制御と免疫寛容の維持. 臨床免疫・アレルギー科. 2019. 71. 497-501

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Patents (3)：

Books (1)：

In Chronic Inflammation: Mechanisms and Regulation, K. Takatsu & M. Miyasaka, ed.
Springer, Japan 2016

Lectures and oral presentations (24)：

Tyrosine kinase inhibitor imatinib augments tumor immunity by depleting effector regulatory T cells
(第16回麒麟塾 2021)
Tregと腫瘍免疫
(Melanoma Conferences 2020)
Cancer immunotherapy targeting regulatory T cells
(第78回日本癌学会学術総会 2019)
Treg-specific control of TCR signaling molecules
(Keystone Symposia: Uncovering Mechanisms of Immune-Based Therapy in Cancer and Autoimmunity (B3) 2019)
制御性T細胞と腫瘍免疫
(Immuno-Checkpoint Blockade Seminar in Osaka 2018 2018)

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Education (1)：

Professional career (1)：

Work history (8)：

2021 - 現在 Immunology Frontier Research Center, Osaka University Associate Professor
2021 - 現在 Graduate School of Medicine, Osaka University Associate Professor
2014 - 2021 Immunology Frontier Research Center, Osaka University Assistant Professor
2014 - 2021 Osaka University Graduate School of Medicine Assistant Professor
2011/04 - 2014/03 Institute for Frontier Medical Sciences, Kyoto University JSPS Postdoctoral Research Fellow

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Awards (7)：

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Association Membership(s) (1)：

THE JAPANESE SOCIETY FOR IMMUNOLOGY

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