Sakata Yasushi

サカタヤスシ | Sakata Yasushi

Affiliation and department：
Job title： Professor

Research field (1)： Cardiology

Research theme for competitive and other funds (22)：

2024 - 2027 治療抵抗性心筋不全の層別化・病態解明とゲノム医療の創出
2024 - 2026 希少心筋症における心筋細胞自律的線維化亢進機序の解明とゲノム医療体制構築
2022 - 2024 重症心不全に潜む不整脈源性心筋症を診断するバイオマーカーの開発
2021 - 2024 Development of clinical practice for rare intractable cardiomyopathy using deep phenotyping combined with iPS cell technology
2021 - 2024 交感神経クロストークによる自己組織化能を用いた心オルガノイド・バイオ人工心臓創出

2019 - 2023 Research on Recovery Behavior of Red Blood Cell with a Hundredfold Drastic Change

2020 - 2022 Development of Human Disease Model of Arrhythmogenic Right Ventricular Cardiomyopathy for Personalized Medicine

2018 - 2021 Elucidation of self-organization of myocardium focusing on cell homing and its application for bio-artificial heart engineering

2018 - 2021 Evaluation for genetic predisposition and clinical pathological stratification in cardiac sarcoidosis

2018 - 2020 Development of upstream therapy targeting molecular basis of refractory cardiomyopathy

2017 - 2020 Usefulness of risk stratification of the patients with heart failure with preserved ejection fraction by multiple biomarkers

2016 - 2019 Elucidation of the molecular mechanism of cardiac energy metabolism for the development of novel therapy for heart failure

2015 - 2019 Cell Exercise toward Elastic Cellular Tissue

2014 - 2019 Development of a new diagnostic method for heart failure in collaboration with drug engineers

2012 - 2015 Impact of Carnitine on Heart Failure with Preserved Ejection Fraction

2011 - 2013 The mechanism of cardio-renal interaction in heart failure-the approach from functional renal reserve-

2009 - 2011 The role of salt sensitivity in the development of heart failure with preserved ejection fraction and the relation of intrinsic steroids

2008 - 2010 Development and measurement of quality indicators to evaluated patient safety and quality improvement in a Japanese university hospital

2007 - 2008 new method to evaluate diastolicfunction using echocardiography

2005 - 2006 Ultrasound imaging for tissue characterization to assess cardiovascular involvement in diabetes

2005 - 2006 Tissue characterization of coronary artery plaque using Intra Vascular Ultrasound RF signal

2005 - 2006 超音波法を用いた新しい拡張期心不全診断法の確立

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Papers (1,056)：

Daisuke Sakamoto, Yohei Sotomi, Yuki Matsuoka, Daisaku Nakatani, Katsuki Okada, Akihiro Sunaga, Hirota Kida, Taiki Sato, Tetsuhisa Kitamura, Masahiro Seo, et al. Prognostic utility and cutoff differences of NT-proBNP level across subgroups in heart failure with preserved ejection fraction: Insights from the PURSUIT-HFpEF Registry. Journal of cardiac failure. 2024
Takahito Kamba, Masahiro Yanagawa, Kazuo Shimamura, Satoshi Yamaguchi, Kenji Shirakura, Satomi Okamura, Yuki Nishimura, Tomomi Yamada, Yasushi Sakata, Noriyuki Tomiyama, et al. First-in-Human Abdominal Aortic Aneurysms Trial with Tricaprin (F-HAAAT): Study Design and Protocol. CJC Open. 2024
Masashi Amano, Misa Takegami, Makoto Miyake, Takeshi Kitai, Tomoyuki Fujita, Tadaaki Koyama, Hidekazu Tanaka, Kenji Ando, Tatsuhiko Komiya, Masaki Izumo, et al. Clinical effects of direct oral anticoagulants in elderly patients with a bioprosthetic valve and atrial fibrillation. International journal of cardiology. 2024. 413. 132375-132375
Naoki Kimoto, Yohei Miyashita, Yutaka Yata, Takeshi Aketa, Masami Yabumoto, Yasushi Sakata, Takashi Washio, Seiji Takashima, Masafumi Kitakaze. Metabolic syndrome is linked to most cancers incidence. Heart and vessels. 2024
Shiro Hoshida, Tetsuya Watanabe, Nobutaka Masunaga, Yukinori Shinoda, Masahiro Seo, Takaharu Hayashi, Masamichi Yano, Takahisa Yamada, Yoshio Yasumura, Shungo Hikoso, et al. Alternative Factors in Possible Involvement of Coronary Microvascular Dysfunction in Older Patients with HFpEF. Journal of clinical medicine. 2024. 13. 19

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MISC (948)：

SASAKI Shun, SHIBA Mikio, HAYASHI Takaharu, YASUNAGA Motoki, HAMANAKA Yuma, KANDA Takashi, MORI Naoki, ICHIBORI Yasuhiro, MINAMIGUCHI Hitoshi, MAKINO Nobuhiko, et al. The Prognostic Impact of Anemia in Heart Failure with Preserved Ejection Fraction with Chronic Kidney Disease. 日本循環器学会学術集会(Web). 2023. 87th
SHIBUYA Yuki, HAYASHI Takaharu, SASAKI Shun, HAMANAKA Yuma, YASUNAGA Motoki, SHIBA Mikio, KANDA Takashi, MORI Naoki, ICHIBORI Yasuhiro, MINAMIGUCHI Hitoshi, et al. The Difference of Risk Factors for Heart Failure Readmission between Low HFA-PEFF Score and High-score in Patients with HFpEF. 日本循環器学会学術集会(Web). 2023. 87th
岡崇史, 関原孝之, 中野智彰, 小津賢太郎, 中村大輔, 世良英子, 溝手勇, 大谷朋仁, 彦惣俊吾, 坂田泰史. CIEDs種類の選択に議論を要した心アミロイドーシス症例. 植込みデバイス関連冬季大会プログラム・抄録集(Web). 2023. 15th
小津賢太郎, 岡崇史, 中野智彰, 関原孝之, 中村大輔, 溝手勇, 大谷朋仁, 彦惣俊吾, 宮川繁, 坂田泰史. 心再同期療法左室リードの閾値上昇に対し心外膜リード留置を施行した1例. 植込みデバイス関連冬季大会プログラム・抄録集(Web). 2023. 15th
坂田泰史, 大谷朋仁. 特発性心筋症の診断・ゲノム情報利活用に関する調査研究. 日本心不全学会学術集会プログラム・抄録集. 2023. 27th (CD-ROM)

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Lectures and oral presentations (9)：

Symposium 5. Practice and Application of Whole Exome Sequencing in Hereditary Heart Disease
(The 2nd JCS Council Forum on Basic Cardiovascular Research, 2019)
Application of Whole Exome Sequencing Data for Detection of Large Genomic Rearrangements in Cardiomyopathy
(The 83rd Annual Scientific Meeting of the Japanese Circulation Society, Meet the expert 11. New topics in cardiomyopathy 2019)
New Insights into the Therapeutic Potential of a KACh Channel in Hereditary Sinus Bradycardia
(The 83rd Annual Scientific Meeting of the Japanese Circulation Society, Symposium 17. Precision Medicine in Inherited Arrhythmias 2019)
循環器疾患の診断と治療
(第4回心エコー図学会 2019)
心不全病態の層別化における疾患ゲノム解析の役割
(第22回日本心不全学会、特別企画8「我が国における循環器病研究の現状と将来展望」 2018)

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Education (2)：

1998 - 2002 大阪大学大学院医学系研究科
1987 - 1993 Osaka University Faculty of Medicine Medical School

Professional career (1)：

医学博士 (大阪大学)

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