Yasuhara Takao

Research field (1)： Neurosurgery

Research keywords (5)：感染症 , 脳神経外傷 , 頭蓋底外科 , 脊椎脊髄外科 , 中枢神経系における再生医療

Research theme for competitive and other funds (27)：

2022 - 2025 Animal model of chronic traumatic encephalopathy and intra-arterial stem cell transplantation: Alteration in tau protein and gene expression
2022 - 2025 Optimized protocol with electrical stimulation and rehabilitation for cell transplantation against cerebral ischemia
2021 - 2024 Elucidation of functional reconstruction in neonatal white matter injury model via oligodendrocyte progenitor cell transplant and exercise
2021 - 2023 脳梗塞に対するSB623細胞移植:カプセル化移植と運動療法併用療法の治療効果を考える
2020 - 2023 -

2020 - 2023 How to activate self-repair in the central nervous system assisted by electrical stimulation?

2019 - 2022 Exploration for the mechanisms of cell therapy by encapsulated cell transplantation

2018 - 2021 Combination treatment of stem cell and exercise therapies in a Wistar Kyoto rat model of traumatic brain injury

2017 - 2020 How to activate endogenous neurogenesis with the use of electrical stimulation?

2017 - 2020 Novel development of combination gene therapy with targeted drug for malignant brain tumor

2017 - 2020 Neurogenesis and depression in the central nervous system disorders

2016 - 2019 Depression and Neurogenesis

2017 - 2018 induction of phenotypic shift of glioma to suppress invasion and to increase chemosensitivity

2014 - 2017 Cell therapy and electrical stimulation for diseases in the central nervous system

2014 - 2017 The combination therapy of novel oncolytic virus with molecular targeted drug

2014 - 2017 The anti-epileptic effect of spinal cord stimulation in kainic acid induced epilepsy rat model

2014 - 2017 The development of novel therapiesfor bevacizumab-induced brain tumor invasion

2013 - 2016 Molecular analysis of invasion and angiogenesis of malignant glioma

2013 - 2016 Does electrical stimulation enhance the migration of transplanted cells in stroke model of rats? : Close up the mechanisms of electrical stimulation and search for the road to clinical application.

2012 - 2014 -

2010 - 2011 -

2009 - 2011 Combined therapy of VEGF plasmid injection and MSC transplantation for Moyamoya disease

2009 - 2011 Can Parkinson's Disease be cured by DBS?

2009 - 2010 -

2008 - 2010 -

2008 - 2009 Combined therapy of MSC transplantation and rehabilitation for Disuse syndrome

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Papers (263)：

Ryo Mizuta, Keigo Makino, Yoshihiro Otai, Kentaro Fujii, Joji Ishida, Atsuhito Uneda, Nobushige Tsuboi, Shuichiro Hirano, Naoya Kemmotsu, Yasuki Suruga, et al. TMIC-31. MOLECULAR PROGNOSTIC FACTORS OF THE PROGRESSION OF VESTIBULAR SCHWANNOMA AFTER PRIMARY TUMOR RESECTION. Neuro-Oncology. 2024. 26. Supplement_8. viii304-viii305
David O. Okonkwo, Peter McAllister, Achal S. Achrol, Yasuaki Karasawa, Masahito Kawabori, Steven C. Cramer, Albert Lai, Santosh Kesari, Benjamin M. Frishberg, Leonid I. Groysman, et al. Mesenchymal Stromal Cell Implants for Chronic Motor Deficits After Traumatic Brain Injury. Neurology. 2024. 103. 7
Fumiyo Higaki, Masafumi Hiramatsu, Takao Yasuhara, Susumu Sasada, Yoshihiro Otani, Jun Haruma, Tomohiro Inoue, Yusuke Morimitsu, Noriaki Akagi, Yusuke Matsui, et al. Cranial and spinal computed tomography (CT) angiography with photon-counting detector CT: comparison with angiographic and operative findings. Japanese journal of radiology. 2024
安原隆雄, 佐々田晋, 金恭平, 伊達勲. 【脳神経外科を取り巻く諸問題】学際的領域における脳神経外科. 脳神経外科ジャーナル. 2024. 33. 8. 529-535
Yosuke Okazaki, Tatsuya Sasaki, Kakeru Hosomoto, Shun Tanimoto, Koji Kawai, Takayuki Nagase, Chiaki Sugahara, Satoru Yabuno, Kyohei Kin, Susumu Sasada, et al. Cervical spinal cord stimulation exerts anti-epileptic effects in a rat model of epileptic seizure through the suppression of CCL2-mediated cascades. Scientific reports. 2024. 14. 1. 14543-14543

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MISC (112)：

安原隆雄, 河内哲, 藪野諭, 永瀬喬之, 菅原千明, 岡崎洋介, 皮居功嗣, 佐々木達也, 佐々田晋, 伊達勲. ヒト骨髄由来加工間葉系幹細胞SB623脳内移植の現状:臨床研究と基礎研究の循環. 日本再生医療学会総会(Web). 2023. 22nd
岡崎洋介, 佐々木達也, 皮居巧嗣, 谷本駿, 永瀬喬之, 菅原千明, 藪野諭, 細本翔, 河内哲, 金一徹, et al. Long-term continuous cervical spinal cord stimulation therapy in a rat model of epilepsy. 日本てんかん外科学会プログラム・抄録集. 2023. 46th
佐々田晋, 古閑比佐志, 安原隆雄, 金恭平, 藪野諭, 菅原千明, 永瀬喬之, 佐々木達也, 伊達勲. L4/5PLIF後に発症したL3/4椎間板ヘルニアにFESS-TFAを行った1例. 日本脊髄外科学会プログラム・抄録集. 2023. 38th
永瀬喬之, 安原隆雄, 三宅隼人, 菅原千明, 藪野諭, 河内哲, 金恭平, 佐々田晋, 伊達勲. ビタミンD抵抗性くる病にOPLLを合併し外科治療を要した1例. 日本脊髄外科学会プログラム・抄録集. 2023. 38th
藪野諭, 安原隆雄, 永瀬喬之, 菅原千明, 河内哲, 金恭平, 佐々田晋, 伊達勲. Chiari奇形1型に対しデュラウェーブを用いて硬膜形成を行った2症例. 日本脊髄外科学会プログラム・抄録集. 2023. 38th

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Books (29)：

脳神経外科手術基本主義のバリエーションー手術のWEB動画55本付きー(脳神経外科速報 2021年増刊)
メディカ出版 2021 ISBN:9784840473460
脳神経外科手術のための術後感染症予防実践マニュアル
メジカルビュー 2021 ISBN:9784758318570
疾患・術式別脳神経外科手術合併症の回避・対処法Q & A 156
メディカ出版 2019
疾患・術式別脳神経外科手術合併症の回避・対処法Q & A 156
メディカ出版 2019
疾患・術式別脳神経外科手術合併症の回避・対処法Q & A 156
メディカ出版 2019

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Lectures and oral presentations (232)：

ビタミンD抵抗性くる病にOPLLを合併し、外科治療を要した1例
(第18回中国四国脊髄外科症例検討会 2022)
大規模データ及びゲノムワイドメチル化解析による毛様細胞性星細胞腫の予後因子の検討
(第40回日本脳腫瘍学会学術集会(現地・Web併催) 2022)
網羅的発言解析を用いた聴神経腫瘍における再発因子の検討
(第40回日本脳腫瘍学会学術集会(現地・Web併催) 2022)
脊椎脊髄外科領域におけるSSIのリスク管理
(第57回日本脊髄障害医学会 2022)
多職種連携による周術期管理の効果-後方視的観察研究による検討-
(日本臨床麻酔学会第42回大会(現地・Web併催) 2022)

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Education (1)：

岡山大学医学部

Professional career (1)：

医学博士

Work history (1)：

岡山大学学術研究院医歯薬学域脳神経外科

Awards (3)：

2006/06 - - Early transplantation of an encapsulated glial cell line-derived neurotrophic factor-producing cell demonstrating strong neuroprotective effects in a rat model of Parkinson disease
2005/10 - The Japan Neurosurgical Society - Early transplantation of an encapsulated glial cell line-derived neurotrophic factor-producing cell demonstrating strong neuroprotective effects in a rat model of Parkinson disease
2005/01 - -

Association Membership(s) (5)：

日本頭蓋底外科学会 , 日本脳神経外傷学会 , 日本脊髄外科学会 , 日本脳神経外科コングレス , 日本脳神経外科学会

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