Rchr
J-GLOBAL ID：201801021447787704   Update date: Jul. 29, 2024

Shun Kageyama

Shun Kageyama
Affiliation and department：
Keio University

About Keio University


Homepage URL  (1)： https://www.thesasakilab.org/ja
Research field  (2)： Cell biology ,  Medical biochemistry
Research keywords  (8)： GTP ,  サルモネラ ,  細胞生物学 ,  protein degradation ,  phase separation ,  Keap1-Nrf2 system ,  p62/Sqstm1 ,  autophagy
Research theme for competitive and other funds  (5)：
  • 2023 - 2026 環境変容に応答した代謝リプログラミング機構の解明
  • 2020 - 2023 選択的オートファジー基質p62/SQSTM1液滴の分子病態の解析
  • 2018 - 2020 Functional analysis of Alfy, a selective autophagy related molecule involved in brain formation
  • 2015 - 2018 Crosstalk between stress granules and autophagy in protein degradation
  • 2014 - 2016 Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway
Papers (34)：
  • 森下 英晃, 来栖 玲央, 藤本 侑生, 能代 大輔, 高田 周平, 山野 晃史, 田中 秀明, 荒井 律子, 蔭山 俊, 船越 智子, et al. オートファジー研究から拡大する細胞質ゾーニングの世界 液-液相分離で形成される"p62 body"の新規構成成分の同定とその選択的オートファジーによる分解意義の解明. 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [3S01m-03]
  • Ryo Ikeda, Daisuke Noshiro, Hideaki Morishita, Shuhei Takada, Shun Kageyama, Yuko Fujioka, Tomoko Funakoshi, Satoko Komatsu-Hirota, Ritsuko Arai, Elena Ryzhii, et al. Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response. The EMBO journal. 2023. e113349
  • Reo Kurusu, Yuki Fujimoto, Hideaki Morishita, Daisuke Noshiro, Shuhei Takada, Koji Yamano, Hideaki Tanaka, Ritsuko Arai, Shun Kageyama, Tomoko Funakoshi, et al. Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex. Developmental cell. 2023
  • Risa Ikutama, Ge Peng, Saya Tsukamoto, Yoshie Umehara, Juan Valentin Trujillo-Paez, Hainan Yue, Hai Le Thanh Nguyen, Miho Takahashi, Shun Kageyama, Masaaki Komatsu, et al. Cathelicidin LL-37 activates human keratinocyte autophagy through the P2X7, mTOR and MAPK pathways. The Journal of investigative dermatology. 2022
  • Ge Peng, Saya Tsukamoto, Risa Ikutama, Hai Le Thanh Nguyen, Yoshie Umehara, Juan V Trujillo-Paez, Hainan Yue, Miho Takahashi, Takasuke Ogawa, Ryoma Kishi, et al. Human β-defensin-3 attenuates atopic dermatitis-like inflammation through autophagy activation and the aryl hydrocarbon receptor signaling pathway. The Journal of clinical investigation. 2022. 132. 17
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MISC (19)：
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Professional career (1)：
  • 博士(理学) (大阪大学)
Work history (4)：
  • 2023/07 - 現在 慶應義塾大学 先端生命科学研究所 生体エネルギー制御グループプロジェクト 特任講師
  • 2019/04 - 2023/06 Juntendo University
  • 2014/04 - 2019/03 Niigata University
  • 2011/04 - 2014/03 Tokyo Metropolitan Institute of Medical Science
Association Membership(s) (1)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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